Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Petra, den Hollander"'
Autor:
Nick A. Kuburich, Petra den Hollander, Maria Castaneda, Mika Pietilä, Ximing Tang, Harsh Batra, Francisco Martínez-Peña, Tanvi H. Visal, Tieling Zhou, Breanna R. Demestichas, Ritesh V. Dontula, Jojo Y. Liu, Joanna Joyce Maddela, Reethi S. Padmanabhan, Lan Thi Hanh Phi, Matthew J. Rosolen, Thiru Sabapathy, Dhiraj Kumar, Filippo G. Giancotti, Luke L. Lairson, Maria Gabriela Raso, Rama Soundararajan, Sendurai A. Mani
Publikováno v:
Cell Reports, Vol 42, Iss 12, Pp 113470- (2023)
Summary: Epithelial-mesenchymal transition (EMT) empowers epithelial cells with mesenchymal and stem-like attributes, facilitating metastasis, a leading cause of cancer-related mortality. Hybrid epithelial-mesenchymal (E/M) cells, retaining both epit
Externí odkaz:
https://doaj.org/article/253d5b2d577048579918e7d5d14d75ec
Autor:
Grace G. Bushnell, Abhijeet P. Deshmukh, Petra den Hollander, Ming Luo, Rama Soundararajan, Dongya Jia, Herbert Levine, Sendurai A. Mani, Max S. Wicha
Publikováno v:
npj Breast Cancer, Vol 7, Iss 1, Pp 1-12 (2021)
Abstract Breast cancer is the most commonly diagnosed cancer in the USA. Although advances in treatment over the past several decades have significantly improved the outlook for this disease, most women who are diagnosed with estrogen receptor positi
Externí odkaz:
https://doaj.org/article/69f901f9c94041478c1dbc00eb262202
Autor:
Geraldine Vidhya Vijay, Na Zhao, Petra Den Hollander, Mike J. Toneff, Robiya Joseph, Mika Pietila, Joseph H. Taube, Tapasree R. Sarkar, Esmeralda Ramirez-Pena, Steven J. Werden, Maryam Shariati, Ruli Gao, Mary Sobieski, Clifford C. Stephan, Nathalie Sphyris, Noayuki Miura, Peter Davies, Jeffrey T. Chang, Rama Soundararajan, Jeffrey M. Rosen, Sendurai A. Mani
Publikováno v:
Breast Cancer Research, Vol 21, Iss 1, Pp 1-14 (2019)
Abstract Background Triple-negative breast cancers (TNBCs), which lack receptors for estrogen, progesterone, and amplification of epidermal growth factor receptor 2, are highly aggressive. Consequently, patients diagnosed with TNBCs have reduced over
Externí odkaz:
https://doaj.org/article/94966eb44ff14ce28f1cf950c225b5fb
Publikováno v:
Seminars in Cancer Biology. 87:17-31
Metastatic cancer is almost always terminal, and more than 90% of cancer deaths result from metastatic disease. Combating cancer metastasis and post-therapeutic recurrence successfully requires understanding each step of metastatic progression. This
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9040e633a3593c110641145095a87308
https://doi.org/10.1016/j.semcancer.2022.10.006
https://doi.org/10.1016/j.semcancer.2022.10.006
Publikováno v:
Seminars in Cancer Biology. 86:816-826
The cytoskeleton plays an integral role in maintaining the integrity of epithelial cells. Epithelial cells primarily employ cytokeratin in their cytoskeleton, whereas mesenchymal cells use vimentin. During the epithelial-mesenchymal transition (EMT),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0abacd70cfe86327bba09a90f0a2e361
https://doi.org/10.1016/j.semcancer.2021.12.006
https://doi.org/10.1016/j.semcancer.2021.12.006
Autor:
Dongya Jia, Mohit Kumar Jolly, Satyendra C. Tripathi, Petra Den Hollander, Bin Huang, Mingyang Lu, Muge Celiktas, Esmeralda Ramirez-Peña, Eshel Ben-Jacob, José N. Onuchic, Samir M. Hanash, Sendurai A. Mani, Herbert Levine
Publikováno v:
Cancer Convergence, Vol 1, Iss 1, Pp 1-19 (2017)
Abstract Background The Epithelial-Mesenchymal Transition (EMT) endows epithelial-looking cells with enhanced migratory ability during embryonic development and tissue repair. EMT can also be co-opted by cancer cells to acquire metastatic potential a
Externí odkaz:
https://doaj.org/article/37e717cba32a44a5b8902ea1d7dfb402
Autor:
Powel H. Brown, Gordon B. Mills, Susan G. Hilsenbeck, Abhijit Mazumdar, Yun Zhang, Nattapon Panupinthu, Jamal Hill, Anna Tsimelzon, Petra den Hollander, Graham M. Poage, Zachary C. Hartman
Table S2 - XLSX file 77K, Verification of lentiviral shRNA knock-down in SUM159 cells by quantitative RT-PCR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71665c170ffe3e13fb05c0313aef8e8b
https://doi.org/10.1158/0008-5472.22397960.v1
https://doi.org/10.1158/0008-5472.22397960.v1
Autor:
Powel H. Brown, Gordon B. Mills, Susan G. Hilsenbeck, Abhijit Mazumdar, Yun Zhang, Nattapon Panupinthu, Jamal Hill, Anna Tsimelzon, Petra den Hollander, Graham M. Poage, Zachary C. Hartman
Figure S5 - PDF file 1389K, Inducible inhibition of IL-6, IL-8, and CXCL1, and tandem inhibition of IL-6, IL-8, and CXCL1 in SUM159, MDA-MB-231, and MDA-MB-468 cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7f8ad93c311087ff2fc66506139d56a
https://doi.org/10.1158/0008-5472.22397972.v1
https://doi.org/10.1158/0008-5472.22397972.v1
Autor:
Powel H. Brown, Gordon B. Mills, Susan G. Hilsenbeck, Abhijit Mazumdar, Yun Zhang, Nattapon Panupinthu, Jamal Hill, Anna Tsimelzon, Petra den Hollander, Graham M. Poage, Zachary C. Hartman
Supplementary Text - PDF file 109K, Supplementary Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06849f7bce73f0b021a28b1cfb53e5ed
https://doi.org/10.1158/0008-5472.22397966
https://doi.org/10.1158/0008-5472.22397966
Autor:
Powel H. Brown, Gordon B. Mills, Susan G. Hilsenbeck, C. Kent Osborne, Jenny C. Chang, Suzanne A.W. Fuqua, Jamal Hill, Abhijit Mazumdar, Jonathan Shepherd, Anna Tsimelzon, Kathryn Rawls, Petra den Hollander
Supp Fig 5 - A) PTP4A3 and Myc amplification status in Luminal A/B and Basal-like breast cancers from TCGA data set. B) PTP4A3 and Myc amplification status in ovarian cancer from TCGA data set. C) Map detailing the location of the genes analyzed for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89a441a43305099efb9472f4efb9fb4f
https://doi.org/10.1158/0008-5472.22408854.v1
https://doi.org/10.1158/0008-5472.22408854.v1