Zobrazeno 1 - 10
of 141
pro vyhledávání: '"Petra, Van Damme"'
Publikováno v:
mBio, Vol 15, Iss 4 (2024)
ABSTRACTIn recent years, it has become evident that the true complexity of bacterial proteomes remains underestimated. Gene annotation tools are known to propagate biases and overlook certain classes of truly expressed proteins, particularly proteofo
Externí odkaz:
https://doaj.org/article/3dd1bc7e155544a3873e1152d176d802
Autor:
Elien Eeckhout, Lisa Hamerlinck, Veronique Jonckheere, Petra Van Damme, Geert van Loo, Andy Wullaert
Publikováno v:
Cell Death and Disease, Vol 14, Iss 4, Pp 1-16 (2023)
Abstract Citrobacter rodentium is an enteropathogen that causes intestinal inflammatory responses in mice reminiscent of the pathology provoked by enteropathogenic and enterohemorrhagic Escherichia coli infections in humans. C. rodentium expresses va
Externí odkaz:
https://doaj.org/article/5979f518de434555b00d37dbbe8ecd50
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
The type III secretion system (T3SS) is a well-studied pathogenicity determinant of many bacteria through which effectors (T3Es) are translocated into the host cell, where they exercise a wide range of functions to deceive the host cell’s immunity
Externí odkaz:
https://doaj.org/article/e64ebd44c35043ad849a5e7288e371c2
Publikováno v:
Frontiers in Plant Science, Vol 12 (2022)
Alternative translation initiation is a widespread event in biology that can shape multiple protein forms or proteoforms from a single gene. However, the respective contribution of alternative translation to protein complexity remains largely enigmat
Externí odkaz:
https://doaj.org/article/0694bd973b604539adb280eec7a6d256
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
With the rapid growth in the number of sequenced genomes, genome annotation efforts became almost exclusively reliant on automated pipelines. Despite their unquestionable utility, these methods have been shown to underestimate the true complexity of
Externí odkaz:
https://doaj.org/article/f7920266f8a54623903ea9b6fed319d5
Autor:
Margaux De Meyer, Igor Fijalkowski, Veronique Jonckheere, Delphine De Sutter, Sven Eyckerman, Petra Van Damme
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
In the context of host-pathogen interactions, gram-negative bacterial virulence factors, such as effectors, may be transferred from bacterial to eukaryotic host cytoplasm by multicomponent Type III protein secretion systems (T3SSs). Central to Salmon
Externí odkaz:
https://doaj.org/article/9c184aa1bd794646802ad8d60a885cd2
Publikováno v:
mSystems, Vol 5, Iss 5 (2020)
ABSTRACT Prokaryotic genome annotation is heavily dependent on automated gene annotation pipelines that are prone to propagate errors and underestimate genome complexity. We describe an optimized proteogenomic workflow that uses ribosome profiling (r
Externí odkaz:
https://doaj.org/article/d37629f750554a13b702882925d5bd97
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
Serving a robust platform for reverse genetics enabling the in vivo study of gene functions primarily in enterobacteriaceae, recombineering -or recombination-mediated genetic engineering-represents a powerful and relative straightforward genetic engi
Externí odkaz:
https://doaj.org/article/14df6e0dc6fb43e5aa7f20e78500a021
Publikováno v:
Microorganisms, Vol 10, Iss 2, p 260 (2022)
Bacteria-host interactions are characterized by the delivery of bacterial virulence factors, i.e., effectors, into host cells where they counteract host immunity and exploit host responses allowing bacterial survival and spreading. These effectors ar
Externí odkaz:
https://doaj.org/article/41c057c5da9a45049b19fa05c3f8b0d9
Autor:
Adam Giess, Veronique Jonckheere, Elvis Ndah, Katarzyna Chyżyńska, Petra Van Damme, Eivind Valen
Publikováno v:
BMC Biology, Vol 15, Iss 1, Pp 1-14 (2017)
Abstract Background While methods for annotation of genes are increasingly reliable, the exact identification of translation initiation sites remains a challenging problem. Since the N-termini of proteins often contain regulatory and targeting inform
Externí odkaz:
https://doaj.org/article/68fa5fb0f59c4bd8a1afd769ef2e1515