Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Petr Zámostný"'
Publikováno v:
Crystals, Vol 13, Iss 3, p 527 (2023)
The impregnation of poorly water-soluble drug onto the surface of a suitable pharmaceutical excipient, used as a hydrophilic carrier, can lead to the preparation of systems with improved dissolution properties due to the separation of drug crystal pa
Externí odkaz:
https://doaj.org/article/c060b0b145d24ccd9d302e4cba5202eb
Publikováno v:
Materials, Vol 16, Iss 4, p 1418 (2023)
Unsaturated C4 hydrocarbons are abundant in various petrochemical streams. They can be considered as a potential feedstock for the steam-cracking process, where they must be co-processed with C6 and higher (C6+) hydrocarbons of primary naphtha fracti
Externí odkaz:
https://doaj.org/article/4a2e0a8e03a94d8ca322d122acb56f4f
Publikováno v:
Pharmaceutics, Vol 14, Iss 10, p 2173 (2022)
Meloxicam (MLX) is a poorly soluble drug exhibiting strong hydrophobicity. This combination of properties makes dissolution enhancement by particle size reduction ineffective; therefore, combined formulation approaches are required. Various approache
Externí odkaz:
https://doaj.org/article/0df6f83fd5d6417abee67dfb828870bd
Publikováno v:
Materials, Vol 14, Iss 4, p 900 (2021)
In the pharmaceutical industry, silicates are commonly used excipients with different application possibilities. They are especially utilized as glidants in low concentrations, but they can be used in high concentrations as porous carriers and coatin
Externí odkaz:
https://doaj.org/article/baf6738e9a9244a8b22ef9fa353d9015
Autor:
Tereza Školáková, Michaela Slámová, Andrea Školáková, Alena Kadeřábková, Jan Patera, Petr Zámostný
Publikováno v:
Pharmaceutics, Vol 11, Iss 8, p 383 (2019)
The aims of this study were to investigate how the release of tadalafil is influenced by two grades of polyvinylpyrrolidone (Kollidon® 12 PF and Kollidon® VA 64) and various methods of preparing solid dispersions (solvent evaporation, spray drying
Externí odkaz:
https://doaj.org/article/0afe321cbb45438e970b31e48df453a8
Publikováno v:
Chemical Engineering Research and Design. 165:467-476
An interactive mixture, i.e. a blend of larger carrier particles with drug particles adhered on their surfaces, is often used in pharmaceutical formulations for promoting powder flow, improving blend uniformity, reducing the segregation risk during m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e321ca324a4c5948c861cdb196cf68d
https://doi.org/10.1016/j.cherd.2020.10.012
https://doi.org/10.1016/j.cherd.2020.10.012
Autor:
Jana Brokešová, Andreas Niederquell, Martin Kuentz, Petr Zámostný, Barbora Vraníková, Zdenka Šklubalová
Publikováno v:
International Journal of Pharmaceutics. 631:122485
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d1ec90f5d3f87ada5b6a838242c34c56
https://doi.org/10.1016/j.ijpharm.2022.122485
https://doi.org/10.1016/j.ijpharm.2022.122485
Autor:
Jana, Brokešová, Andreas, Niederquell, Martin, Kuentz, Petr, Zámostný, Barbora, Vraníková, Zdenka, Šklubalová
Publikováno v:
International Journal of Pharmaceutics. 626:122198
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36d2a08e76773ac738a4c855f20b1d20
https://doi.org/10.1016/j.ijpharm.2022.122198
https://doi.org/10.1016/j.ijpharm.2022.122198
Autor:
Michaela Slámová, Petra Svačinová, Lukáš Krejčík, Zdenka Šklubalová, Barbora Vraníková, Jana Brokešová, Petr Zámostný, Martin Kuentz, Jakub Koktan
Publikováno v:
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 169
To enhance dissolution rate of meloxicam (MX), a poorly soluble model drug, a natural polysaccharide excipient chitosan (CH) is employed in this work as a carrier to prepare binary interactive mixtures by either mixing or co-milling techniques. The M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccdc7f69d7d184eb3d12e73f5c6943e2
https://pubmed.ncbi.nlm.nih.gov/34863871
https://pubmed.ncbi.nlm.nih.gov/34863871
Publikováno v:
AAPS PharmSciTech. 22
In direct compression of tablets, it is crucial to maintain content uniformity within acceptable margins, especially in formulations with low drug loading. To assure it, complex and multistep mixing processes are utilized in the industry. In this stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da67ae7520312fdaeaee97b2748d36ca
https://doi.org/10.1208/s12249-021-02073-z
https://doi.org/10.1208/s12249-021-02073-z