Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Petr Unichenko"'
Autor:
Daniel Minge, Cátia Domingos, Petr Unichenko, Charlotte Behringer, Alberto Pauletti, Stefanie Anders, Michel K. Herde, Andrea Delekate, Polina Gulakova, Susanne Schoch, Gabor C. Petzold, Christian Henneberger
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2021)
The fine processes of single astrocytes can contact many thousands of synapses whose function they can modulate through bi-directional signaling. The spatial arrangement of astrocytic processes and neuronal structures is relevant for such interaction
Externí odkaz:
https://doaj.org/article/01476609db6c4d2cb092389cbc0e5087
Autor:
Johannes Vogt, Jenq‐Wei Yang, Arian Mobascher, Jin Cheng, Yunbo Li, Xingfeng Liu, Jan Baumgart, Carine Thalman, Sergei Kirischuk, Petr Unichenko, Guilherme Horta, Konstantin Radyushkin, Albrecht Stroh, Sebastian Richers, Nassim Sahragard, Ute Distler, Stefan Tenzer, Lianyong Qiao, Klaus Lieb, Oliver Tüscher, Harald Binder, Nerea Ferreiros, Irmgard Tegeder, Andrew J Morris, Sergiu Gropa, Peter Nürnberg, Mohammad R Toliat, Georg Winterer, Heiko J Luhmann, Jisen Huai, Robert Nitsch
Publikováno v:
EMBO Molecular Medicine, Vol 8, Iss 1, Pp 25-38 (2015)
Abstract Loss of plasticity‐related gene 1 (PRG‐1), which regulates synaptic phospholipid signaling, leads to hyperexcitability via increased glutamate release altering excitation/inhibition (E/I) balance in cortical networks. A recently reported
Externí odkaz:
https://doaj.org/article/d9725db74d88432db8fdfb78fb4c4402
Autor:
Julian Karpf, Petr Unichenko, Nicholas Chalmers, Felix Beyer, Marie-Theres Wittmann, Julia Schneider, Elif Fidan, Andre Reis, Jan Beckervordersandforth, Sebastian Brandner, Stefan Liebner, Sven Falk, Andreas Sagner, Christian Henneberger, Ruth Beckervordersandforth
Publikováno v:
Nature Neuroscience, 25(12), 1626-1638. Nature Publishing Group
Nature neuroscience 25(12), 1626-1638 (2022). doi:10.1038/s41593-022-01192-5
Nature neuroscience 25(12), 1626-1638 (2022). doi:10.1038/s41593-022-01192-5
Neuronal heterogeneity has been established as a pillar of higher central nervous system function, but glial heterogeneity and its implications for neural circuit function are poorly understood. Here we show that the adult mouse dentate gyrus (DG) of
Autor:
Sarel J. Fleishman, Hiromu Monai, Björn Breithausen, Vanessa Vongsouthi, Leon Kremers, Joshua A. Mitchell, Christian Henneberger, Harald Janovjak, Petr Unichenko, Colin J. Jackson, Jason H. Whitfield, Hajime Hirase, Olga Khersonsky
Publikováno v:
ACS Sensors
ACS sensors 6(11), 4193-4205 (2021). doi:10.1021/acssensors.1c01803
ACS sensors 6(11), 4193-4205 (2021). doi:10.1021/acssensors.1c01803
Solute-binding proteins (SBPs) have evolved to balance the demands of ligand affinity, thermostability, and conformational change to accomplish diverse functions in small molecule transport, sensing, and chemotaxis. Although the ligand-induced confor
Autor:
Petr Unichenko, Gabor C. Petzold, Catia Domingos, Alberto Pauletti, Charlotte Behringer, Stefanie Anders, Susanne Schoch, Daniel Minge, Polina E. Gulakova, Christian Henneberger, Andrea Delekate, Michel K. Herde
Publikováno v:
Frontiers in Cellular Neuroscience
Frontiers in Cellular Neuroscience, Vol 15 (2021)
Frontiers in cellular neuroscience 15, 669280 (2021). doi:10.3389/fncel.2021.669280
Frontiers in Cellular Neuroscience, Vol 15 (2021)
Frontiers in cellular neuroscience 15, 669280 (2021). doi:10.3389/fncel.2021.669280
The fine processes of single astrocytes can contact many thousands of synapses whose function they can modulate through bi-directional signaling. The spatial arrangement of astrocytic processes and neuronal structures is relevant for such interaction
Autor:
Jenq-Wei Yang, Heiko J. Luhmann, Matthieu Hammer, Dilja Krueger-Burg, Sergei Kirischuk, Petr Unichenko, Werner Kilb, Nils Brose, Sergei N. Kolbaev
Publikováno v:
Cerebral Cortex. 28:2873-2886
Neuroligin-4 (Nlgn4) is a cell adhesion protein that regulates synapse organization and function. Mutations in human NLGN4 are among the causes of autism spectrum disorders. In mouse, Nlgn4 knockout (KO) perturbs GABAergic synaptic transmission and o
Publikováno v:
Cell Calcium. 60:322-330
Myelination in the central nervous system depends on axon-oligodendrocyte precursor cell (OPC) interaction. We suggest that myelin synthesis may be influenced by [Na+]i and [Ca2+]i signaling in OPCs. Experiments were performed in mouse cultured OPCs
Autor:
Heiko J. Luhmann, Jenq-Wei Yang, Sergei Kirischuk, Robert Nitsch, Patrick Schneider, Guilherme Horta, Thomas Roskoden, Petr Unichenko, Konstantin Radyushkin, Angela Sommer, Jan Baumgart, Johannes Vogt
Publikováno v:
Cerebral Cortex (New York, NY)
Plasticity-related gene-1 (PRG-1) is a brain-specific protein that modulates glutamatergic synaptic transmission. Here we investigated the functional role of PRG-1 in adolescent and adult mouse barrel cortex both in vitro and in vivo. Compared with w
Autor:
Lianyong Qiao, Sebastian Richers, Petr Unichenko, Sergei Kirischuk, Peter Nürnberg, Heiko J. Luhmann, Johannes Vogt, Georg Winterer, Jin Cheng, Arian Mobascher, Albrecht Stroh, Jenq-Wei Yang, Guilherme Horta, Mohammad R. Toliat, Carine Thalman, Sergiu Gropa, Robert Nitsch, Ute Distler, Nerea Ferreirós, Nassim Sahragard, Harald Binder, Yunbo Li, Konstantin Radyushkin, Stefan Tenzer, Andrew J. Morris, Irmgard Tegeder, Jan Baumgart, Klaus Lieb, Xingfeng Liu, Oliver Tüscher, Jisen Huai
Publikováno v:
EMBO Molecular Medicine. 8:25-38
Loss of plasticity-related gene 1 (PRG-1), which regulates synaptic phospholipid signaling, leads to hyperexcitability via increased glutamate release altering excitation/inhibition (E/I) balance in cortical networks. A recently reported SNP in prg-1
Autor:
Heiko J. Luhmann, Jenq-Wei Yang, Petr Unichenko, Sergei Kirischuk, Werner Kilb, Maik C. Stüttgen
Publikováno v:
Current opinion in neurobiology. 53
This review provides an overview on the development of the rodent whisker-to-barrel cortex system from late embryonic stage to the end of the first postnatal month. During this period the system shows a remarkable transition from a mostly genetic-mol