Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Petr Tvrdik"'
Autor:
Khadijeh A. Sharifi, Faraz Farzad, Sauson Soldozy, Matthew R. DeWitt, Richard J. Price, Jason Sheehan, M. Yashar S. Kalani, Petr Tvrdik
Publikováno v:
Frontiers in Neuroscience, Vol 18 (2024)
The Wnt pathway plays critical roles in neurogenesis. The expression of Axin2 is induced by Wnt/β-catenin signaling, making this gene a reliable indicator of canonical Wnt activity. We employed pulse-chase genetic lineage tracing with the Axin2-CreE
Externí odkaz:
https://doaj.org/article/78bd6b542a894e4eb89e852a906b7354
Autor:
Jennifer D. Sokolowski, Sauson Soldozy, Khadijeh A. Sharifi, Pedro Norat, Kathryn N. Kearns, Lei Liu, Ashley M. Williams, Kaan Yağmurlu, Panagiotis Mastorakos, G. Wilson Miller, M. Yashar S. Kalani, Min S. Park, Ryan T. Kellogg, Petr Tvrdik
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
Stroke remains a major burden on patients, families, and healthcare professionals, despite major advances in prevention, acute treatment, and rehabilitation. Preclinical basic research can help to better define mechanisms contributing to stroke patho
Externí odkaz:
https://doaj.org/article/f27a5a27e1ab4c8cad22c1e02a0929a5
Autor:
Pedro Norat, Jennifer D. Sokolowski, Catherine M. Gorick, Sauson Soldozy, Jeyan S. Kumar, Youngrok Chae, Kaan Yagmurlu, Joelle Nilak, Khadijeh A. Sharifi, Melanie Walker, Michael R. Levitt, Alexander L. Klibanov, Zhen Yan, Richard J. Price, Petr Tvrdik, Mohammad Yashar S. Kalani
Publikováno v:
Stroke: Vascular and Interventional Neurology, Vol 3, Iss 3 (2023)
Background Transplantation of autologous mitochondria into ischemic tissue may mitigate injury caused by ischemia and reperfusion. Methods Using murine stroke models of middle cerebral artery occlusion, we sought to evaluate feasibility of delivery o
Externí odkaz:
https://doaj.org/article/a6e7164fe9c346a3b137fecd1e55ef7b
Autor:
Pedro Norat, Sauson Soldozy, Jennifer D. Sokolowski, Catherine M. Gorick, Jeyan S. Kumar, Youngrok Chae, Kaan Yağmurlu, Francesco Prada, Melanie Walker, Michael R. Levitt, Richard J. Price, Petr Tvrdik, M. Yashar S. Kalani
Publikováno v:
npj Regenerative Medicine, Vol 5, Iss 1, Pp 1-9 (2020)
Abstract Mitochondria are fundamental for metabolic homeostasis in all multicellular eukaryotes. In the nervous system, mitochondria-generated adenosine triphosphate (ATP) is required to establish appropriate electrochemical gradients and reliable sy
Externí odkaz:
https://doaj.org/article/b0a1c19e85e34debbdbd0050424db0b5
Autor:
Sauson Soldozy, Daniel K. Akyeampong, David L. Barquin, Pedro Norat, Kaan Yağmurlu, Jennifer D. Sokolowski, Khadijeh A. Sharifi, Petr Tvrdik, Min S. Park, M. Yashar S. Kalani
Publikováno v:
Frontiers in Surgery, Vol 7 (2020)
Objective: The goal of this study was to systematically review functional mapping and reorganization that takes place in the setting of arteriovenous malformations (AVMs) and its potential impact on grading and surgical decision making.Methods: A sys
Externí odkaz:
https://doaj.org/article/09bebb4b403446019d6f790996f1dde3
Autor:
Pedro Norat, Sauson Soldozy, Mazin Elsarrag, Jennifer Sokolowski, Kaan Yaǧmurlu, Min S. Park, Petr Tvrdik, M. Yashar S. Kalani
Publikováno v:
Frontiers in Surgery, Vol 6 (2019)
Establishing blood vessel patency in neurovascular surgery is an essential component in treating cerebrovascular disorders. Given the difficulty in confirming complete obliteration of the aneurysm sac, ICG videoangiography has emerged as an intraoper
Externí odkaz:
https://doaj.org/article/09591d1bacda49938d2da0848f7c1611
Autor:
Pedro Norat, Sauson Soldozy, Jennifer D. Sokolowski, Catherine M. Gorick, Jeyan S. Kumar, Youngrok Chae, Kaan Yağmurlu, Francesco Prada, Melanie Walker, Michael R. Levitt, Richard J. Price, Petr Tvrdik, M. Yashar S. Kalani
Publikováno v:
npj Regenerative Medicine, Vol 6, Iss 1, Pp 1-1 (2021)
A Correction to this paper has been published: https://doi.org/10.1038/s41536-021-00125-3
Externí odkaz:
https://doaj.org/article/8edf1edd0957461fb2ba2502ece3c6ed
Autor:
Kaan Yağmurlu, Jennifer D. Sokolowski, Musa Çırak, Kamran Urgun, Sauson Soldozy, Melike Mut, Mark E. Shaffrey, Petr Tvrdik, M. Yashar S. Kalani
Publikováno v:
Brain Sciences, Vol 10, Iss 12, p 953 (2020)
Background: Studies in rodents have re-kindled interest in the study of lymphatics in the central nervous system. Animal studies have demonstrated that there is a connection between the subarachnoid space and deep cervical lymph nodes (DCLNs) through
Externí odkaz:
https://doaj.org/article/cb766ad179f9411d85be93a016ebb40c
Autor:
James S Ruff, Raed B Saffarini, Leda L Ramoz, Linda C Morrison, Shambralyn Baker, Sean M Laverty, Petr Tvrdik, Mario R Capecchi, Wayne K Potts
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0174975 (2017)
Here we assess the fitness consequences of the replacement of the Hoxa1 coding region with its paralog Hoxb1 in mice (Mus musculus) residing in semi-natural enclosures. Previously, this Hoxa1B1 swap was reported as resulting in no discernible embryon
Externí odkaz:
https://doaj.org/article/23b571f354d54b03ac292e40dc4aadfe
Autor:
Damir Zadravec, Petr Tvrdik, Hervé Guillou, Richard Haslam, Tsutomu Kobayashi, Johnathan A. Napier, Mario R. Capecchi, Anders Jacobsson
Publikováno v:
Journal of Lipid Research, Vol 52, Iss 2, Pp 245-255 (2011)
ELOVL2 is a member of the mammalian microsomal ELOVL fatty acid enzyme family, involved in the elongation of very long-chain fatty acids including PUFAs required for various cellular functions in mammals. Here, we used ELOVL2-ablated (Elovl2−/−)
Externí odkaz:
https://doaj.org/article/b1383565787346cca5b8dbf8689de1eb