Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Petr Rada"'
Autor:
Abhijith Makki, Sami Kereïche, Tien Le, Jitka Kučerová, Petr Rada, Vojtěch Žárský, Ivan Hrdý, Jan Tachezy
Publikováno v:
BMC Biology, Vol 22, Iss 1, Pp 1-15 (2024)
Abstract Background Hydrogenosomes are a specific type of mitochondria that have adapted for life under anaerobiosis. Limited availability of oxygen has resulted in the loss of the membrane-associated respiratory chain, and consequently in the genera
Externí odkaz:
https://doaj.org/article/579f6b6493394d4f86a39024d2dece8b
Publikováno v:
Journal of Microbiology, Immunology and Infection, Vol 55, Iss 2, Pp 191-198 (2022)
Background: Trichomonas vaginalis is the causative agent of a sexually transmitted disease in humans. The virulence of the parasite depends on multiple factors, including the presence of endosymbiotic dsRNA viruses. The presence of Trichomonasviruses
Externí odkaz:
https://doaj.org/article/eb713333ab624084a28e7700d6345f0a
Autor:
Petr Rada, Ivan Hrdý, Alois Zdrha, Ravi Kumar Narayanasamy, Tamara Smutná, Jana Horáčková, Karel Harant, Vladimír Beneš, Seow-Chin Ong, Chih-Yu Tsai, Hong-Wei Luo, Cheng-Hsun Chiu, Petrus Tang, Jan Tachezy
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Trichomonas vaginalis is a parasitic protist that infects the human urogenital tract. During the infection, trichomonads adhere to the host mucosa, acquire nutrients from the vaginal/prostate environment, and release small extracellular vesicles (sEV
Externí odkaz:
https://doaj.org/article/3a1c9c196a4342ad82545dc3434c9b2d
Autor:
Zdeněk Verner, Vojtěch Žárský, Tien Le, Ravi Kumar Narayanasamy, Petr Rada, Daniel Rozbeský, Abhijith Makki, Darja Belišová, Ivan Hrdý, Marie Vancová, Corinna Lender, Constantin König, Iris Bruchhaus, Jan Tachezy
Publikováno v:
PLoS Pathogens, Vol 17, Iss 11, p e1010041 (2021)
Entamoeba histolytica is believed to be devoid of peroxisomes, like most anaerobic protists. In this work, we provided the first evidence that peroxisomes are present in E. histolytica, although only seven proteins responsible for peroxisome biogenes
Externí odkaz:
https://doaj.org/article/dc06638efbb447139fcaa75a65277540
Triplet-pore structure of a highly divergent TOM complex of hydrogenosomes in Trichomonas vaginalis.
Autor:
Abhijith Makki, Petr Rada, Vojtěch Žárský, Sami Kereïche, Lubomír Kováčik, Marian Novotný, Tobias Jores, Doron Rapaport, Jan Tachezy
Publikováno v:
PLoS Biology, Vol 17, Iss 1, p e3000098 (2019)
Mitochondria originated from proteobacterial endosymbionts, and their transition to organelles was tightly linked to establishment of the protein import pathways. The initial import of most proteins is mediated by the translocase of the outer membran
Externí odkaz:
https://doaj.org/article/bad9d30d5895419291f26e35a901fc49
Autor:
Neritza Campo Beltrán, Lenka Horváthová, Petr L Jedelský, Miroslava Sedinová, Petr Rada, Michaela Marcinčiková, Ivan Hrdý, Jan Tachezy
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e65148 (2013)
Iron plays a crucial role in metabolism as a key component of catalytic and redox cofactors, such as heme or iron-sulfur clusters in enzymes and electron-transporting or regulatory proteins. Limitation of iron availability by the host is also one of
Externí odkaz:
https://doaj.org/article/3e9b056bed6d470c812e781419f57616
Autor:
Petr L Jedelský, Pavel Doležal, Petr Rada, Jan Pyrih, Ondřej Smíd, Ivan Hrdý, Miroslava Sedinová, Michaela Marcinčiková, Lubomír Voleman, Andrew J Perry, Neritza Campo Beltrán, Trevor Lithgow, Jan Tachezy
Publikováno v:
PLoS ONE, Vol 6, Iss 2, p e17285 (2011)
The mitosomes of Giardia intestinalis are thought to be mitochondria highly-reduced in response to the oxygen-poor niche. We performed a quantitative proteomic assessment of Giardia mitosomes to increase understanding of the function and evolutionary
Externí odkaz:
https://doaj.org/article/712b0b57a5fb41aaa83449a5fe13180a
Autor:
Petr Rada, Pavel Doležal, Petr L Jedelský, Dejan Bursac, Andrew J Perry, Miroslava Šedinová, Kateřina Smíšková, Marian Novotný, Neritza Campo Beltrán, Ivan Hrdý, Trevor Lithgow, Jan Tachezy
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24428 (2011)
Trichomonas vaginalis is a parasitic protist of the Excavata group. It contains an anaerobic form of mitochondria called hydrogenosomes, which produce hydrogen and ATP; the majority of mitochondrial pathways and the organellar genome were lost during
Externí odkaz:
https://doaj.org/article/4a85c2b4c3944902a285239084830607
Autor:
Seow-Chin Ong, Wei-Hung Cheng, Fu-Man Ku, Chih-Yu Tsai, Po-Jung Huang, Chi-Ching Lee, Yuan-Ming Yeh, Petr Rada, Ivan Hrdý, Ravi Kumar Narayanasamy, Tamara Smutná, Rose Lin, Hong-Wei Luo, Cheng-Hsun Chiu, Jan Tachezy, Petrus Tang
Publikováno v:
Genes; Volume 13; Issue 3; Pages: 531
Accumulated evidence suggests that the endosymbiotic Trichomonasvirus (TVV) may play a role in the pathogenesis and drug susceptibility of Trichomonas vaginalis. Several reports have shown that extracellular vesicles (EVs) released from TVV-positive
Autor:
Jan Tachezy, Eva Nývltová, Tien Le, Petr Rada, Vojtěch Žárský, Marie Vancová, Ivan Hrdý, Karel Harant, Zdeněk Verner
Publikováno v:
Proceedings of the National Academy of Sciences
The adaptation of eukaryotic cells to anaerobic conditions is reflected by substantial changes to mitochondrial metabolism and functional reduction. Hydrogenosomes belong among the most modified mitochondrial derivative and generate molecular hydroge