Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Petr Niederhafner"'
Autor:
Jaroslav Šebestík, Petr Niederhafner, Timothy A. Keiderling, Petr Bouř, Martin Šafařík, Jitka Neburkova
Publikováno v:
Amino acids. 53(4)
Oxidative stress can lead to various derivatives of the tyrosine residue in peptides and proteins. A typical product is 3-nitro-L-tyrosine residue (Nit), which can affect protein behavior during neurodegenerative processes, such as those associated w
Autor:
Petr Niederhafner, Jaroslav Šebestík, Hana Šestáková, Martin Šafařík, Romana Hadravová, Mohamed Farouk Hamissa
Publikováno v:
Journal of Molecular Structure. 1250:131828
One of the strategies to combat neurodegenerative diseases such as Alzheimer's and Parkinson's diseases, or to heal brain injuries is based on the regeneration of neurons. Inubosin B is acridine alkaloid with neuroregenerative potential. The understa
Publikováno v:
Amino Acids. 48:1087-1098
3-Nitrotyrosine (Nit) belongs to products of oxidative stress and could probably influence conformation of neurodegenerative proteins. Syntheses of peptides require availability of suitable synthon for introduction of Nit residue. Common phenolic pro
Autor:
Mohamed Farouk Hamissa, Hana Šestáková, Martin Šafařík, Petr Niederhafner, Leah Koutná, Jaroslav Šebestík, Radko Souček, Lenka Kolářová, Marta Telus
Publikováno v:
Tetrahedron Letters. 61:152641
Inubosin B is the most active member of the acridine alkaloids isolated from Streptomyces sp. IFM 11440 culture. The inubosins initiate neuroregeneration via a neurogenine 2 pathway. In this work, we have described the total synthesis of inubosin B v
Publikováno v:
Amino Acids. 51:1689-1690
This errata is for paper "Rapid acidolysis of benzyl group as a suitable approach for syntheses.
Autor:
Erich Wünsch, Vladimír Gut, Jan Hlaváček, Petr Niederhafner, Václav Kašička, Jan Ježek, Miloš Buděšínský
Publikováno v:
Amino Acids. 39:641-650
Synthetic study on cystinyl peptides using solution and solid phase methodology was carried out with the central hinge region of immunoglobulin IgG1. In the solid phase synthesis of hexadecapeptide 1c, the time necessary for the formation of disulfid
Publikováno v:
Journal of Peptide Science. 14:2-43
Glycopeptide dendrimers are branched structures containing both carbohydrates and peptides. Various classes of these compounds differing in composition and structure are mentioned, together with their practical use spanning from catalysis, transport
Publikováno v:
Journal of Peptide Science. 14:44-65
Glycopeptide dendrimers are regularly branched structures containing both carbohydrates and peptides. Various types of these compounds differing in composition and structure are mentioned, together with their practical use spanning from catalysis, tr
Publikováno v:
International Journal of Peptide Research and Therapeutics. 11:291-296
A useful method for monitoring of peptide synthesis on polyethylene glycol (PEG) was developed and is described in this paper. The course of reactions such as loading, acylation, detachment and others where a charge of reactant and product differ, ca
Publikováno v:
Tetrahedron Letters. 47:1023-1025
Peptides from the hinge region of human IgG1 are potential defined carriers of synthetic immunogens. Their synthesis was carried out on the soluble support—PEG-OMe 2000 using disulfide bond synthons. The loading capacity of the polymer was increase