Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Petr Maly"'
Publikováno v:
Journal of Biomedical Science, Vol 31, Iss 1, Pp 1-16 (2024)
Abstract Human immunodeficiency virus type 1 (HIV-1) vaccine immunogens capable of inducing broadly neutralizing antibodies (bNAbs) remain obscure. HIV-1 evades immune responses through enormous diversity and hides its conserved vulnerable epitopes o
Externí odkaz:
https://doaj.org/article/188eec09a91b4c02873a0e0284bafd18
Autor:
Leona Raskova Kafkova, Joanna M. Mierzwicka, Prosenjit Chakraborty, Petr Jakubec, Ondrej Fischer, Jozef Skarda, Petr Maly, Milan Raska
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Non-small cell lung cancer (NSCLC) is largely promoted by a multistep tumorigenesis process involving various genetic and epigenetic alterations, which essentially contribute to the high incidence of mortality among patients with NSCLC. Clinical obse
Externí odkaz:
https://doaj.org/article/9ea9c310c79145f588c8e0fcd68b2a5b
Autor:
Petr Kosztyu, Milan Kuchar, Jiri Cerny, Lucia Barkocziova, Michal Maly, Hana Petrokova, Lydie Czernekova, Veronika Liskova, Leona Raskova Kafkova, Pavlina Knotigova, Josef Masek, Jaroslav Turanek, Petr Maly, Milan Raska
Publikováno v:
EBioMedicine, Vol 47, Iss , Pp 247-256 (2019)
Background: The development of an effective vaccine preventing HIV-1 infection is hindered by the enormous antigenic variability and unique biochemical and immunological properties of HIV-1 Env glycoprotein, the most promising target for HIV-1 neutra
Externí odkaz:
https://doaj.org/article/766038e16e974b7fb6d548862f5e1bfd
Publikováno v:
Cytokine & Growth Factor Reviews. 66:1-14
IL-6 is considered one of the well characterized cytokines exhibiting homeostatic, pro- and anti-inflammatory activities, depending on the receptor variant and the induced intracellular cis- or trans-signaling responses. IL-6-activated pathways are i
Autor:
Marek Maly, Jiri Cerny, Petr Kosztyu, Petr Maly, Lucia Barkocziova, Jaroslav Turánek, Pavlína Turánek Knotigová, Veronika Liskova, Milan Raska, Lýdie Czerneková, Josef Mašek, Milan Kuchar, Hana Petroková, L. Raskova Kafkova
Publikováno v:
EBioMedicine. 47:247-256
Background: The development of effective vaccine preventing HIV-1 infection is hindered by enormous antigenic variability and unique biochemical and immunological properties of HIV-1 Env glycoprotein, the most promising target for HIV-1 neutralizing
Publikováno v:
Sensors and Actuators B: Chemical. 272:441-447
Recent developments in molecular evolution technologies have led to novel types of high-affinity recombinant protein binders (PB) able to substitute antibodies in many diagnostic and therapeutic applications. Despite almost a decade of research, they
Autor:
Peter Sebo, Marek Maly, Dietmar Appelhans, Ondrej Stanek, Jan Frolik, Marcel Štofik, Dominika Wrobel, Jan Čermák, Lucie Červenková Št’astná, Jan Maly, Milan Kuchar, Petr Maly, Franka Ennen, Tereza Knapova, Alena Semerádtová
Publikováno v:
Macromolecular Bioscience. 16:553-566
For the design of a biohybrid structure as a ligand-tailored drug delivery system (DDS), it is highly sophisticated to fabricate a DDS based on smoothly controllable conjugation steps. This article reports on the synthesis and the characterization of
Autor:
Vlasta Splichalova, Karel Smetana, Jirina Bartunkova, Dita Mayerova, Petr Maly, Radek Klubal, Anna Sediva, Ales Sedlacek
Publikováno v:
APMIS. 108:409-416
Deficiencies in adhesion molecules or their counter-receptors in humans may have severe consequences as exemplified by leukocyte adhesion deficiency (LAD) I or II syndromes. Because such diseases occur with great rarity, animal models are valuable fo
Autor:
Walimbwa, Stephen Ian1 (AUTHOR) Stephenian.walimbwa01@upol.cz, Maly, Petr2 (AUTHOR), Kafkova, Leona Raskova3 (AUTHOR), Raska, Milan1,3 (AUTHOR) milan.raska@upol.cz
Publikováno v:
Journal of Biomedical Science. 8/21/2024, Vol. 31 Issue 1, p1-16. 16p.
Akademický článek
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