Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Petr Kuzmič"'
Autor:
Xiaoxin Chen, Xiaodong Huang, Qinhai Ma, Petr Kuzmič, Biao Zhou, Jinxin Xu, Bin Liu, Haiming Jiang, Wenjie Zhang, Chunguang Yang, Shiguan Wu, Jianzhou Huang, Haijun Li, Chaofeng Long, Xin Zhao, Hongrui Xu, Yanan Sheng, Yaoting Guo, Chuanying Niu, Lu Xue, Yong Xu, Jinsong Liu, Tianyu Zhang, James Spencer, Wenbin Deng, Shu-Hui Chen, Xiaoli Xiong, Zifeng Yang, Nanshan Zhong
SARS-CoV-2 has demonstrated extraordinary ability to evade antibody immunity by antigenic drift. Small molecule drugs may provide effective therapy while being part of a solution to circumvent SARS-CoV-2 immune escape. In this study we report an α-k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb636ef6720c3a87a37c9ca83831c699
https://doi.org/10.21203/rs.3.rs-2634509/v1
https://doi.org/10.21203/rs.3.rs-2634509/v1
Publikováno v:
Biochemistry. 55:5279-5288
Inosine-5'-monophosphate dehydrogenase (IMPDH) catalyzes the conversion of inosine 5'-monophosphate (IMP) to xanthosine 5'-monophosphate (XMP). The enzyme is an emerging target for antimicrobial therapy. The small molecule inhibitor A110 has been ide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7a7c79adc5ad7f65646fd47a9b0cea3
https://doi.org/10.1021/acs.biochem.6b00265
https://doi.org/10.1021/acs.biochem.6b00265
Autor:
Petr Kuzmič
Publikováno v:
Molecular and Cellular Endocrinology. 248:172-181
A generalized numerical treatment of rapid-equilibrium enzyme kinetics is presented. This new approach relies on automatic computer derivation of the underlying mathematical model (a system of simultaneous nonlinear algebraic equations) from a symbol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc604fd7e134d9a7b6506c326d92e394
https://doi.org/10.1016/j.mce.2005.10.012
https://doi.org/10.1016/j.mce.2005.10.012
Publikováno v:
Collection of Czechoslovak Chemical Communications. 58:565-574
Reduction of C-Cl bonds in 2,2-dichloro-1,1,2-trifluoroethyl trichloromethyl ether (I), 2-chloro-1,1,2-trifluoroethyl trichloromethyl ether (II), and 2,2-dichloro-1,1,2-trifluoroethyl dichloromethyl ether (III) with 2-propanol, 2-butanol, cyclohexano
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df4dc46c25a6fa5c06ebfef14f3aa5ef
https://doi.org/10.1135/cccc19930565
https://doi.org/10.1135/cccc19930565
Publikováno v:
ChemInform. 24
Reduction of C-Cl bonds in 2,2-dichloro-1,1,2-trifluoroethyl trichloromethyl ether ( I ), 2-chloro-1,1,2-trifluoroethyl trichloromethyl ether ( II ), and 2,2-dichloro-1,1,2-trifluoroethyl dichloromethyl ether ( III ) with 2-propanol, 2-butanol, cyclo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::146bce9d53d335472720d4a59534595e
https://doi.org/10.1002/chin.199333125
https://doi.org/10.1002/chin.199333125
Autor:
Petr, Kuzmič
Publikováno v:
Methods in enzymology. 467
Since its original publication, the DynaFit software package [Kuzmic, P. (1996). Program DYNAFIT for the analysis of enzyme kinetic data: Application to HIV proteinase. Anal. Biochem. 237, 260-273] has been used in more than 500 published studies. Mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c8349d61d982bbf1134eb40142f4cdbf
https://pubmed.ncbi.nlm.nih.gov/19897096
https://pubmed.ncbi.nlm.nih.gov/19897096
Publikováno v:
Peptides ISBN: 9789401050050
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da189bcd797aca633c9c5704087ffd29
https://doi.org/10.1007/978-94-011-2264-1_316
https://doi.org/10.1007/978-94-011-2264-1_316
Publikováno v:
Peptides ISBN: 9789401050050
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d3c5522cd197661eb94f65f70c31108
https://doi.org/10.1007/978-94-011-2264-1_180
https://doi.org/10.1007/978-94-011-2264-1_180
Publikováno v:
Collection of Czechoslovak Chemical Communications. 52:2482-2491
Anaerobic photolysis of dimethoxynitrobiphenyls IIIa-VIa in aqueous alkaline tert-butanol gave products of nucleophilic photosubstitution of methoxyl by hydroxide anion, while the dimethoxybiphenyls Ia and IIa were found unreactive. Regioselectivity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2dccfff9770790d0c98a5c6fc34783b4
https://doi.org/10.1135/cccc19872482
https://doi.org/10.1135/cccc19872482
Publikováno v:
Collection of Czechoslovak Chemical Communications. 51:1665-1670
Irradiation of 3,4-dimethoxy-1-nitrobenzene in the presence of butylamine leads to the formation of both possible photosubstitution products, i.e., 2-methoxy-4-nitro-N-butylaniline and 2-methoxy-5-nitro-N-butylaniline with the predominance of the lat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a7271b94741c8d27ce1cc24e750aea6
https://doi.org/10.1135/cccc19861665
https://doi.org/10.1135/cccc19861665