Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Petr Kašpárek"'
Autor:
Tomáš Takáč, Pavel Křenek, George Komis, Pavol Vadovič, Miroslav Ovečka, Ludmila Ohnoutková, Tibor Pechan, Petr Kašpárek, Tereza Tichá, Jasim Basheer, Mark Arick, Jozef Šamaj
Publikováno v:
Frontiers in Plant Science, Vol 12 (2021)
Mitogen activated protein kinases (MAPKs) integrate elicitor perception with both early and late responses associated with plant defense and innate immunity. Much of the existing knowledge on the role of plant MAPKs in defense mechanisms against micr
Externí odkaz:
https://doaj.org/article/088b44a5ddfc4dc6aa7628a6629a2cd3
Autor:
Alena Karnošová, Veronika Strnadová, Blanka Železná, Jaroslav Kuneš, Petr Kašpárek, Lenka Maletínská
Publikováno v:
Clinical Science. 137:847-862
A previous study on neuropeptide FF receptor 2 (NPFFR2)-deficient mice has demonstrated that NPFFR2 is involved in the control of energy balance and thermogenesis. Here, we report on the metabolic impact of NPFFR2 deficiency in male and female mice t
Autor:
Petr Nickl, Irena Jenickova, Jan Elias, Petr Kasparek, Cyril Barinka, Jana Kopkanova, Radislav Sedlacek
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Site-specific recombinases (SSRs) are critical for achieving precise spatiotemporal control of engineered alleles. These enzymes play a key role in facilitating the deletion or inversion of loci flanked by recombination sites, resulting in t
Externí odkaz:
https://doaj.org/article/79cca0ad81ff48a8a1b67a0712663e5a
Autor:
Monika Nedomova, Stefanie Haberecht-Müller, Sophie Möller, Simone Venz, Michaela Prochazkova, Jan Prochazka, Frantisek Sedlak, Kallayanee Chawengsaksophak, Elke Hammer, Petr Kasparek, Michael Adamek, Radislav Sedlacek, Jan Konvalinka, Elke Krüger, Klara Grantz Saskova
Publikováno v:
iScience, Vol 27, Iss 10, Pp 110893- (2024)
Summary: DDI2 is an aspartic protease that cleaves polyubiquitinated substrates. Upon proteotoxic stress, DDI2 activates the transcription factor TCF11/NRF1 (NFE2L1), crucial for maintaining proteostasis in mammalian cells, enabling the expression of
Externí odkaz:
https://doaj.org/article/8fa378f6b0684b9892e996b65ed983a4
Autor:
Julian Petersen, Lukas Englmaier, Artem V. Artemov, Irina Poverennaya, Ruba Mahmoud, Thibault Bouderlique, Marketa Tesarova, Ruslan Deviatiiarov, Anett Szilvásy-Szabó, Evgeny E. Akkuratov, David Pajuelo Reguera, Hugo Zeberg, Marketa Kaucka, Maria Eleni Kastriti, Jan Krivanek, Tomasz Radaszkiewicz, Kristína Gömöryová, Sarah Knauth, David Potesil, Zbynek Zdrahal, Ranjani Sri Ganji, Anna Grabowski, Miriam E. Buhl, Tomas Zikmund, Michaela Kavkova, Håkan Axelson, David Lindgren, Rafael Kramann, Christoph Kuppe, Ferenc Erdélyi, Zoltán Máté, Gábor Szabó, Till Koehne, Tibor Harkany, Kaj Fried, Jozef Kaiser, Peter Boor, Csaba Fekete, Jan Rozman, Petr Kasparek, Jan Prochazka, Radislav Sedlacek, Vitezslav Bryja, Oleg Gusev, Igor Adameyko
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-22 (2023)
Abstract In this study we use comparative genomics to uncover a gene with uncharacterized function (1700011H14Rik/C14orf105/CCDC198), which we hereby name FAME (Factor Associated with Metabolism and Energy). We observe that FAME shows an unusually hi
Externí odkaz:
https://doaj.org/article/28aaada8bdf44462afbe36b53f7e9fc6
Autor:
Frantisek Spoutil, Goretti Aranaz-Novaliches, Michaela Prochazkova, Tomas Wald, Vendula Novosadova, Petr Kasparek, Radim Osicka, Janne E. Reseland, Staale P. Lyngstadaas, Hanna Tiainen, Kristyna Bousova, Jiri Vondrasek, Radislav Sedlacek, Jan Prochazka
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Highly specialized enamel matrix proteins (EMPs) are predominantly expressed in odontogenic tissues and diverged from common ancestral gene. They are crucial for the maturation of enamel and its extreme complexity in multiple independent lin
Externí odkaz:
https://doaj.org/article/9cee86c6099c4e5593b71dbfde9ce7ab
Autor:
Zora Novakova, Mirko Milosevic, Zsofia Kutil, Marketa Ondrakova, Barbora Havlinova, Petr Kasparek, Cristian Sandoval-Acuña, Zuzana Korandova, Jaroslav Truksa, Marek Vrbacky, Jakub Rohlena, Cyril Barinka
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-17 (2022)
Abstract In humans, disruptions in the heme biosynthetic pathway are associated with various types of porphyrias, including variegate porphyria that results from the decreased activity of protoporphyrinogen oxidase IX (PPO; E.C.1.3.3.4), the enzyme c
Externí odkaz:
https://doaj.org/article/c8c3edc54eb849c18d405c9c691a81f8
Publikováno v:
Folia Microbiologica. 52:331-338
Mutations extended the host range of the polyvalent bacteriophage 812 of the family Myoviridae in up to 95 % of Staphylococcus aureus strains and 43 % of strains of different coagulase-positive and -negative Staphylococcus species. Mutational changes
Autor:
Lenka Hernychová, Jan Preisler, Hana Konečná, Roman Pantůček, Zbyněk Zdráhal, Petr Kašpárek, Jiří Doškař, Luděk Eyer, Vladislava Růžičková
Publikováno v:
PROTEOMICS. 7:64-72
Phage 812 is a polyvalent phage with a very broad host range in the genus Staphylococcus, which makes it a suitable candidate for phage therapy of staphylococcal infections. This proteomic study, combining the results of both 1-DE and 2-DE followed b
Autor:
Nataliia Pavliuchenko, Iris Duric, Jarmila Kralova, Matej Fabisik, Frantisek Spoutil, Jan Prochazka, Petr Kasparek, Jana Pokorna, Tereza Skopcova, Radislav Sedlacek, Tomas Brdicka
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
IntroductionAutoinflammatory diseases are characterized by dysregulation of innate immune system leading to spontaneous sterile inflammation. One of the well-established animal models of this group of disorders is the mouse strain Pstpip2cmo. In this
Externí odkaz:
https://doaj.org/article/26500fa665154620ac4ba6875d226417