Zobrazeno 1 - 10 of 23 pro vyhledávání: '"Petr Hainz"'
1
Akademický článek
Non-Mutated Nucleophosmin 1 Is Recognized by the CD8+ T Lymphocytes of an AML Patient after the Transplantation of Hematopoietic Stem Cells from an HLA-Haploidentical Donor
Autor: Sarka Nemeckova, Kamila Alexova-Zurkova, Petr Hainz, Jitka Krystofova, Jana Mackova, Katerina Roubalova, Marketa Stastna-Markova, Milena Vrana, Jan Vydra
Publikováno v: Current Oncology, Vol 29, Iss 5, Pp 2928-2934 (2022)
Nucleophosmin (NPM1, B23) is a multifunctional phosphoprotein expressed in all tissues. The protein is mainly localized in nucleoli. In hematological malignancies, NPM1 belongs to commonly altered genes. Its mutation, always heterozygous, leads to th
Externí odkaz: https://doaj.org/article/25cd0e5b37d34af998eeb9653ed9fb99
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2
Akademický článek
Pretransplant BK Virus-Specific T-Cell-Mediated Immunity and Serotype Specific Antibodies May Have Utility in Identifying Patients at Risk of BK Virus-Associated Haemorrhagic Cystitis after Allogeneic HSCT
Autor: Markéta Šťastná-Marková, Eva Hamšíková, Petr Hainz, Petr Hubáček, Marie Kroutilová, Jitka Kryštofová, Viera Ludvíková, Jan Musil, Pavla Pecherková, Martina Saláková, Vojtěch Šroller, Jan Vydra, Šárka Němečková
Publikováno v: Vaccines, Vol 9, Iss 11, p 1226 (2021)
BK polyomavirus (BKPyV) persists lifelong in renal and urothelial cells with asymptomatic urinary shedding in healthy individuals. In some immunocompromised persons after transplantation of hematopoietic stem cells (HSCT), the BKPyV high-rate replica
Externí odkaz: https://doaj.org/article/7460f6432f664b1c8d82438383122ca2
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4
Antigenic competition in the generation of multi-virus-specific cell lines for immunotherapy of human cytomegalovirus, polyomavirus BK, Epstein-Barr virus and adenovirus infection in haematopoietic stem cell transplant recipients
Autor: Jitka Krystofova, Kateřina Roubalová, Petr Hainz, Eva Hamsikova, Markéta Pumannová, Šárka Němečková
Publikováno v: Immunology Letters. 228:64-69
Adoptive transfer of multivirus-specific T cell lines (MVST) is an advanced tool for immunotherapy of virus infections after hematopoietic stem cell transplantation (HSCT). Their preparation includes activation of donor virus-specific T cells by the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::361135d1c17650c8393281c4e18111f2
https://doi.org/10.1016/j.imlet.2020.09.009
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5
Pretransplant BK Virus-Specific T-Cell-Mediated Immunity and Serotype Specific Antibodies May Have Utility in Identifying Patients at Risk of BK Virus-Associated Haemorrhagic Cystitis after Allogeneic HSCT
Autor: Viera Ludvíková, Marie Kroutilová, Eva Hamsikova, Petr Hubacek, Petr Hainz, Jan Musil, Vojtěch Šroller, Jitka Krystofova, Pavla Pecherková, Jan Vydra, Martina Salakova, Markéta Šťastná-Marková, Šárka Němečková
Publikováno v: Vaccines, Vol 9, Iss 1226, p 1226 (2021)
Vaccines
Volume 9
Issue 11
BK polyomavirus (BKPyV) persists lifelong in renal and urothelial cells with asymptomatic urinary shedding in healthy individuals. In some immunocompromised persons after transplantation of hematopoietic stem cells (HSCT), the BKPyV high-rate replica
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbe1bd77816f339cb8134ba35efae692
https://www.mdpi.com/2076-393X/9/11/1226
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7
Expression of soluble TGF-β receptor II by recombinant Vaccinia virus enhances E7 specific immunotherapy of HPV16 tumors
Autor: Petr Chlanda, J Krystofova, Petr Hainz, K Zurkova, L. Kutinová, K. Babiarova, Samkova Z, Sarka Nemeckova
Publikováno v: Neoplasma. 58:181-188
Therapeutic immunization with double recombinants of vaccinia virus (VACV) co-expressing sTβRII increased rejection of established TC-1 tumors in C57BL/6 mice in comparison with single recombinant expressing SigE7LAMP. Recombinant VACV derived from
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::610af9babbb42569f6ca8f256fe43ab5
https://doi.org/10.4149/neo_2011_03_181
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8
Reconstitution of cytomegalovirus-specific T-cell response in allogeneic hematopoietic stem cell recipients: the contribution of six frequently recognized, virus-encoded ORFs
Autor: Petr Hainz, K. Babiarova, V. Sroller, M. Maly, S Nemeckova, M. Stastna-Markova, J. Musil, J Krystofova
Publikováno v: Transplant infectious disease : an official journal of the Transplantation Society. 18(3)
Background The reactivation of human cytomegalovirus (HCMV) in immunosuppressed patients is associated with significant morbidity. Testing HCMV-specific T-cell responses can help determine which patients are at high risk of HCMV disease. We optimized
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25830d4984d63bc9e515a3170e17f9f5
https://pubmed.ncbi.nlm.nih.gov/27061389
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9
Prime/boost immunotherapy of HPV16-induced tumors with E7 protein delivered by Bordetella adenylate cyclase and modified vaccinia virus Ankara
Autor: L. Kutinová, Pavel Gabriel, Peter Sebo, Jana Stasikova, Petr Hainz, Sarka Nemeckova, Marcela Simsova, Jiri Masin, Jana Mackova
Publikováno v: Cancer Immunology, Immunotherapy. 55:39-46
The Bordetella adenylate cyclase toxoid (CyaA) targets cells expressing the alphaMbeta2 integrin receptor CD11b/CD18 (CR3 or Mac-1) and can penetrate into cytosol of professional antigen-presenting cells, such as dendritic cells. This allows us to us
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27b8904f548bbac400e771a92b30c2ea
https://doi.org/10.1007/s00262-005-0700-7
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