Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Petr Dobes"'
Autor:
Petr Dobes, Miroslav Pohanka
Publikováno v:
International Journal of Molecular Sciences, Vol 14, Iss 5, Pp 9873-9882 (2013)
Caffeine is an alkaloid with a stimulant effect in the body. It can interfere in transmissions based on acetylcholine, epinephrine, norepinephrine, serotonin, dopamine and glutamate. Clinical studies indicate that it can be involved in the slowing of
Externí odkaz:
https://doaj.org/article/8a070f03e4c94ee99577849576cb9859
Autor:
Martina Takacova, Joanna Obacz, Borivoj Vojtesek, Silvia Pastorekova, Roman Hrstka, Petr Dobes, Veronika Brychtová
Publikováno v:
European Journal of Cell Biology. 94:139-147
In the past decades, highly related members of the protein disulphide isomerase family, anterior gradient protein AGR2 and AGR3, attracted researchers’ attention due to their putative involvement in developmental processes and carcinogenesis. While
Publikováno v:
Journal of Applied Biomedicine. 12:285-290
Alzheimer disease (AD) is the most common cause of progressive dementia in the elderly population, with prevalence of 5% after 65 year of age and is increasing to about 30% in people over 85 year. AD is a neurodegenerative and incurable disease. Curr
Autor:
Borivoj Vojtesek, Oldrich Coufal, Roman Hrstka, Andrea Jurečková, Petr Dobes, Katarína Petráková, Jan Podhorec
Publikováno v:
Oncology Reports. 32:1695-1702
High rates of mutation in the TP53 tumor suppressor gene have been found in many human cancers, including breast tumors, making p53 one of the most studied proteins in oncology. However, the prognostic and predictive value of alterations in this gene
Autor:
Petr Dobes, Zdena Dobesova
Publikováno v:
Applied Mechanics and Materials. :355-358
ArcGIS and AutoCAD Map 3D are both geographic information system (GIS) software. Both are used worldwide in many countries and companies. The dataflow design in visual editors is suitable for daily work. Visual languages are valuable for wide user co
Protein glycation has been implicated in various disease states and is therefore an important process in aging and age-related chronic diseases. At the molecular level, protein glycation has important implications for protein activity, unfolding and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ea24a121afe397416a7085f07051f52
Publikováno v:
Journal of GEOsciences. :81-104
*Corresponding author Epithermal gold mineralization in quartz veins forms part of a large ore belt extending in the NW–SE direction parallel to the Cordillera de Tilaran, Costa Rica. It is confined to Miocene–Pliocene andesites and basalts of th
Autor:
Tamara Sidorinova, Petr Dobes
Publikováno v:
Geoscience Research Reports.
Publikováno v:
The Journal of Physical Chemistry B. 115:8581-8589
In the present study, we have investigated complexes of CK2 protein kinase with halogenated inhibitors by means of the advanced semiempirical quantum mechanical (SQM) PM6 method (called PM6-DH2X), which describes various types of noncovalent interact
Publikováno v:
Journal of Computer-Aided Molecular Design. 25:223-235
A semiempirical quantum mechanical PM6-DH2 method accurately covering the dispersion interaction and H-bonding was used to score fifteen structurally diverse CDK2 inhibitors. The geometries of all the complexes were taken from the X-ray structures an