Zobrazeno 1 - 10
of 113
pro vyhledávání: '"Petr Džubák"'
Autor:
Marianne Fleuti, Tania Sanchez-Quirante, Lenka Poštová Slavětínská, Eva Tloušt'ová, Michal Tichý, Soňa Gurská, Petr Džubák, Marián Hajdúch, Michal Hocek
Publikováno v:
ACS Omega, Vol 9, Iss 18, Pp 20557-20570 (2024)
Externí odkaz:
https://doaj.org/article/9fd51b42b0dc460dae1b9022e978c82e
Autor:
Jiří Řehulka, Michal Jurášek, Pavel Dráber, Aleksandra Ivanová, Soňa Gurská, Kateřina Ječmeňová, Olena Mokshyna, Marián Hajdúch, Pavel Polishchuk, Pavel B. Drašar, Petr Džubák
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 39, Iss 1 (2024)
Estradiol dimers (EDs) possess significant anticancer activity by targeting tubulin dynamics. In this study, we synthesised 12 EDs variants via copper-catalysed azide-alkyne cycloaddition (CuAAC) reaction, focusing on structural modifications within
Externí odkaz:
https://doaj.org/article/c6ffcd1be2c54765a90525facd8c6a33
Autor:
Vani Madhuri Velavalapalli, Venkatanarayana Chowdary Maddipati, Soňa Gurská, Narendran Annadurai, Barbora Lišková, Naresh Kumar Katari, Petr Džubák, Marián Hajdúch, Viswanath Das, Rambabu Gundla
Publikováno v:
ACS Omega, Vol 9, Iss 7, Pp 8067-8081 (2024)
Externí odkaz:
https://doaj.org/article/dcac0aed7d23459baaba501d8cac8aec
Autor:
Valeria Skopelidou, Pavel Hurník, Lubomír Tulinský, Vladimir Židlík, Jiří Lenz, Patricie Delongová, Helena Hornychová, Patrik Flodr, Tomáš Jelínek, Ludmila Muroňová, Dušan Holub, Petr Džubák, Marián Hajdúch
Publikováno v:
Pathology and Oncology Research, Vol 29 (2023)
Amyloidosis is a rare metabolic disorder primarily brought on by misfolding of an autologous protein, which causes its local or systemic deposition in an aberrant fibrillar form. It is quite rare for pulmonary tissue to be impacted by amyloidosis; of
Externí odkaz:
https://doaj.org/article/5d3b44f9f4df42ba8e3705192ece15a0
Autor:
Joyce E. Gutiérrez, Hegira Ramírez, Esteban Fernandez-Moreira, María E. Acosta, Michael R. Mijares, Juan Bautista De Sanctis, Soňa Gurská, Petr Džubák, Marián Hajdúch, Liesangerli Labrador-Fagúndez, Bruno G. Stella, Luis José Díaz-Pérez, Gustavo Benaim, Jaime E. Charris
Publikováno v:
Pharmaceuticals, Vol 16, Iss 12, p 1709 (2023)
A series of heterocyclic chloroquine hybrids, containing a chain of two carbon atoms at position four of the quinolinic chain and acting as a link between quinoline and several benzoyl groups, is synthesized and screened in vitro as an inhibitor of
Externí odkaz:
https://doaj.org/article/c3ae8e752e514bfdab501d036bed6509
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
This study presents the very first report on the in vitro antiviral activity of selected essential oils of Lamiaceae plant species and their monoterpenes against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Nineteen essential oils we
Externí odkaz:
https://doaj.org/article/69f36b39352f45158db7fd36503594f7
Autor:
Lucia Veselovská, Radek Pohl, Eva Tloušt′ová, Soňa Gurská, Petr Džubák, Marián Hajdúch, Michal Hocek
Publikováno v:
ACS Omega, Vol 5, Iss 40, Pp 26278-26286 (2020)
Externí odkaz:
https://doaj.org/article/da63e6d1e1a848d88919a30a79a6038a
Autor:
Tomáš Oždian, Jan Vodička, Jiří Dostál, Dušan Holub, Jana Václavková, Michal Ješeta, Barbora Hamerníková, Pavla Kouřilová, Ondřej Malchar, Vladimír Dvořák, Pavel Hejtmánek, Kateřina Sobková, Pavel Ventruba, Radovan Pilka, Petr Džubák, Marián Hajdúch
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 2, p 1038 (2023)
Cervical mucus (CM) is a viscous fluid that is produced by the cervical glands and functions as a uterine cervix plug. Its viscosity decreases during ovulation, providing a window for non-invasive sampling. This study focuses on proteomic characteriz
Externí odkaz:
https://doaj.org/article/787ad88ec84143a9986cb131c801abed
Autor:
Joyce E. Gutiérrez, Esteban Fernandez-Moreira, Miguel A. Rodríguez, Michael R. Mijares, Juan Bautista De Sanctis, Soňa Gurská, Petr Džubák, Marián Hajdůch, Julia Bruno-Colmenarez, Luis Rojas, Denis Deffieux, Laurent Pouységu, Stéphane Quideau, Jaime Charris, Hegira Ramírez
Publikováno v:
Pharmaceuticals, Vol 15, Iss 10, p 1234 (2022)
A series of 78 synthetic 7-chloro-(4-thioalkylquinoline) derivatives were investigated for cytotoxic activity against eight human cancer as well as 4 non-tumor cell lines. The results showed, with some exceptions, that sulfanyl 5–40 and sulfinyl 41
Externí odkaz:
https://doaj.org/article/ec01600f92cc479f85cac12e2bcbc218
Mixture Effects of Tryptophan Intestinal Microbial Metabolites on Aryl Hydrocarbon Receptor Activity
Autor:
Aneta Vrzalová, Petra Pečinková, Peter Illés, Soňa Gurská, Petr Džubák, Martin Szotkowski, Marián Hajdúch, Sridhar Mani, Zdeněk Dvořák
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 18, p 10825 (2022)
Aryl hydrocarbon receptor (AHR) plays pivotal roles in intestinal physiology and pathophysiology. Intestinal AHR is activated by numerous dietary, endogenous, and microbial ligands. Whereas the effects of individual compounds on AHR are mostly known,
Externí odkaz:
https://doaj.org/article/bbe414ea573344799271833a751af8dc