Zobrazeno 1 - 10
of 122
pro vyhledávání: '"Petr Hodek"'
Publikováno v:
Cosmetics, Vol 11, Iss 2, p 33 (2024)
Cytochrome P450 (CYP) enzymes play a key role in the metabolism of foreign compounds and in the biosynthesis and catabolism of endogenous substances, including hormones. The activity of these enzymes can be affected by various xenobiotics, such as po
Externí odkaz:
https://doaj.org/article/68de8717ba484b91843d38ec5e0ca848
Autor:
Kateřina Bělonožníková, Eliška Sladkovská, Daniel Kavan, Veronika Hýsková, Petr Hodek, Daniel Šmíd, Helena Ryšlavá
Publikováno v:
Molecules, Vol 28, Iss 3, p 1019 (2023)
Pseudomonas aeruginosa is one of the most antibiotic multi-resistant bacteria, causing chronic pulmonary disease and leading to respiratory failure and even mortality. Thus, there has been an ever-increasing search for novel and preferably natural an
Externí odkaz:
https://doaj.org/article/a82a77ae8f0b43af95aacf8f920c95d7
Publikováno v:
Biomedicines, Vol 8, Iss 12, p 547 (2020)
Herein, the in vitro metabolism of tyrosine kinase inhibitor cabozantinib, the drug used for the treatment of metastatic medullary thyroid cancer and advanced renal cell carcinoma, was studied using hepatic microsomal samples of different human donor
Externí odkaz:
https://doaj.org/article/a49d55891bc547c19c2ebc52e3eb3fd4
Publikováno v:
Prague Medical Report, Vol 116, Iss 1, Pp 16-23 (2015)
Isolated porcine pepsinogen A was used for the preparation of polyclonal rabbit and polyclonal chicken anti-pepsinogen A antibodies. Immunochemical properties of both immunoglobulin fractions were compared. The rabbit anti-serum was further purified
Externí odkaz:
https://doaj.org/article/2753f8f6b6824468942d3db2c8bc43e5
Autor:
Libuše Nosková, Božena Kubíčková, Lucie Vašková, Barbora Bláhová, Michaela Wimmerová, Marie Stiborová, Petr Hodek
Publikováno v:
Sensors, Vol 15, Iss 1, Pp 1945-1953 (2015)
Antibodies against Pseudomonas aeruginosa (PA) lectin, PAIIL, which is a virulence factor mediating the bacteria binding to epithelium cells, were prepared in chickens and purified from egg yolks. To examine these antibodies as a prophylactic agent p
Externí odkaz:
https://doaj.org/article/e40418ec02ec4759b629651920a1e5e3
Publikováno v:
Journal of Applied Biomedicine. 19:149-158
Myricetin (MYR) and dihydromyricetin (DHM) are classified as natural flavonoids. Both substances are known for their anti-inflammatory and antioxidant properties. In this study, an in vitro model of inflammation was demonstrated on monolayers of scra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a1de5b23250d2a35506edbf20d1f3d4
https://doi.org/10.32725/jab.2021.017
https://doi.org/10.32725/jab.2021.017
Publikováno v:
Sensors, Vol 14, Iss 12, Pp 22982-22997 (2014)
The requirements for early diagnostics as well as effective treatment of cancer diseases have increased the pressure on development of efficient methods for targeted drug delivery as well as imaging of the treatment success. One of the most recent ap
Externí odkaz:
https://doaj.org/article/78223966f3a34148bf3df5347575f2ee
Autor:
Lenka Malinovská, Son Thai Le, Mihály Herczeg, Michaela Vašková, Josef Houser, Eva Fujdiarová, Jan Komárek, Petr Hodek, Anikó Borbás, Michaela Wimmerová, Magdolna Csávás
Publikováno v:
Biomolecules, Vol 9, Iss 11, p 686 (2019)
Pseudomonas aeruginosa is an opportunistic human pathogen associated with cystic fibrosis. This bacterium produces, among other virulence factors, a soluble d-galactose-specific lectin PA-IL (LecA). PA-IL plays an important role in the adhesion to th
Externí odkaz:
https://doaj.org/article/6f3bc813d91644b0ab8304e3f78b4aa2
Autor:
Son Thai Le, Lenka Malinovska, Michaela Vašková, Erika Mező, Viktor Kelemen, Anikó Borbás, Petr Hodek, Michaela Wimmerová, Magdolna Csávás
Publikováno v:
Molecules, Vol 24, Iss 12, p 2262 (2019)
Series of multivalent α-l-fucoside containing glycoclusters and variously decorated l-fucosides were synthesized to find potential inhibitors of fucose-specific lectins and study the structure-binding affinity relationships. Tri- and tetravalent fuc
Externí odkaz:
https://doaj.org/article/ed045b77c5634298af2b940f44e68d6c
Autor:
Václav Martínek, František Bárta, Volker M. Arlt, Petr Hodek, Kevin Kotalík, Marie Stiborová, Alena Dedı́ková, Šárka Dušková, Jaroslav Mráz
Publikováno v:
Chemical Research in Toxicology. 33:2804-2818
The plant extract aristolochic acid (AA), containing aristolochic acid I (AAI) and II (AAII) as major components, causes aristolochic acid nephropathy and Balkan endemic nephropathy, unique renal d...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d4fcfd17751f58285c1aa40c80804a8f
https://doi.org/10.1021/acs.chemrestox.0c00198
https://doi.org/10.1021/acs.chemrestox.0c00198