Výsledky vyhledávání - "Petráčková, A."

Akademický článek

T3SS chaperone of the CesT family is required for secretion of the anti-sigma factor BtrA in Bordetella pertussis

Autor: Jakub Držmíšek, Denisa Petráčková, Ana Dienstbier, Ivana Čurnová, Branislav Večerek

Publikováno v: Emerging Microbes and Infections, Vol 12, Iss 2 (2023)

Bordetella pertussis is a Gram-negative, strictly human re-emerging respiratory pathogen and the causative agent of whooping cough. Similar to other Gram-negative pathogens, B. pertussis produces the type III secretion system, but its role in the pat

Externí odkaz: https://doaj.org/article/768a7091d3594313b1ff7bd7e4f55dd8

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Akademický článek

Avirulent phenotype promotes Bordetella pertussis adaptation to the intramacrophage environment

Autor: Mariam R. Farman, Denisa Petráčková, Dilip Kumar, Jakub Držmíšek, Argha Saha, Ivana Čurnová, Jan Čapek, Václava Hejnarová, Fabian Amman, Ivo Hofacker, Branislav Večerek

Publikováno v: Emerging Microbes and Infections, Vol 12, Iss 1 (2023)

ABSTRACTBordetella pertussis, the causative agent of whooping cough, is an extracellular, strictly human pathogen. However, it has been shown that B. pertussis cells can escape phagocytic killing and survive in macrophages upon internalization. Our t

Externí odkaz: https://doaj.org/article/821ce2959aed4031b8fc2ce8f67adc55

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Akademický článek

Characterization of the input material quality for the production of tisagenlecleucel by multiparameter flow cytometry and its relation to the clinical outcome

Autor: Martin Štach, Robert Pytlík, Kristýna Šmilauerová, Jana Rychlá, Martin Mucha, Jan Musil, Abhishek Koladiya, Matěj Nemec, Martina Petráčková, Iva Kaštánková, Pavla Pecherková, Lucie Šrámková, Kamila Polgárová, Marek Trněný, Petr Lesný, Jan Vydra, Pavel Otáhal

Publikováno v: Pathology and Oncology Research, Vol 29 (2023)

Tisagenlecleucel (tisa-cel) is a CD19-specific CAR-T cell product approved for the treatment of relapsed/refractory (r/r) DLBCL or B-ALL. We have followed a group of patients diagnosed with childhood B-ALL (n = 5), adult B-ALL (n = 2), and DLBCL (n =

Externí odkaz: https://doaj.org/article/1d9dc7c6b478480589b2506dafb816b3

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Akademický článek

NPM1 and DNMT3A mutations are associated with distinct blast immunophenotype in acute myeloid leukemia

Autor: Kateřina Kuželová, Barbora Brodská, Jana Marková, Martina Petráčková, Johannes Schetelig, Šárka Ransdorfová, Zdenka Gašová, Cyril Šálek

Publikováno v: OncoImmunology, Vol 11, Iss 1 (2022)

The immune system is important for elimination of residual leukemic cells during acute myeloid leukemia (AML) therapy. Anti-leukemia immune response can be inhibited by various mechanisms leading to immune evasion and disease relapse. Selected marker

Externí odkaz: https://doaj.org/article/4ab2548210ad4b5ab7f7e51955cc9c58

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Akademický článek

Comparative Omics Analysis of Historic and Recent Isolates of Bordetella pertussis and Effects of Genome Rearrangements on Evolution

Autor: Ana Dienstbier, Fabian Amman, Denisa Petráčková, Daniel Štipl, Jan Čapek, Jana Zavadilová, Kateřina Fabiánová, Jakub Držmíšek, Dilip Kumar, Mark Wildung, Derek Pouchnik, Branislav Večerek

Publikováno v: Emerging Infectious Diseases, Vol 27, Iss 1, Pp 57-68 (2021)

Despite high vaccination coverage, pertussis is increasing in many industrialized countries, including the Czech Republic. To better understand Bordetella pertussis resurgence, we analyzed historic strains and recent clinical isolates by using a comp

Externí odkaz: https://doaj.org/article/25de9abc0e174758a512f2bdad1e48a1

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