Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Petr, Chlanda"'
Autor:
Liv Zimmermann, Xiaohan Zhao, Jana Makroczyova, Moritz Wachsmuth-Melm, Vibhu Prasad, Zach Hensel, Ralf Bartenschlager, Petr Chlanda
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract Coronavirus replication is associated with the remodeling of cellular membranes, resulting in the formation of double-membrane vesicles (DMVs). A DMV-spanning pore was identified as a putative portal for viral RNA. However, the exact compone
Externí odkaz:
https://doaj.org/article/ec898bd6b18840459e8a9139b107c87a
Autor:
Fabio Lolicato, Julia P Steringer, Roberto Saleppico, Daniel Beyer, Jaime Fernandez-Sobaberas, Sebastian Unger, Steffen Klein, Petra Riegerová, Sabine Wegehingel, Hans-Michael Müller, Xiao J Schmitt, Shreyas Kaptan, Christian Freund, Martin Hof, Radek Šachl, Petr Chlanda, Ilpo Vattulainen, Walter Nickel
Publikováno v:
eLife, Vol 12 (2024)
Fibroblast growth factor 2 (FGF2) exits cells by direct translocation across the plasma membrane, a type I pathway of unconventional protein secretion. This process is initiated by phosphatidylinositol-4,5-bisphosphate (PI(4,5)P2)-dependent formation
Externí odkaz:
https://doaj.org/article/2e4e6e3f4925498a9fc2d1adf0169274
Autor:
Bianca S. Bodmer, Melina Vallbracht, Dmitry S. Ushakov, Lisa Wendt, Petr Chlanda, Thomas Hoenen
Publikováno v:
Emerging Microbes and Infections, Vol 12, Iss 2 (2023)
Viral RNA synthesis of several non-segmented, negative-sense RNA viruses (NNSVs) takes place in inclusion bodies (IBs) that show properties of liquid organelles, which are formed by liquid–liquid phase separation of scaffold proteins. It is believe
Externí odkaz:
https://doaj.org/article/0710fdb8a91d42d8bb641e184a8ff62c
Autor:
Steffen Klein, Benedikt H. Wimmer, Sophie L. Winter, Androniki Kolovou, Vibor Laketa, Petr Chlanda
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
Using the post-correlation on-lamella cryo-CLEM workflow, Klein, Wimmer et al. show that lamellar bodies (LBs) are composed of membrane sheets frequently attached to the limiting membrane through T-junctions in ABCA3 overexpressing cells and in prima
Externí odkaz:
https://doaj.org/article/32ea53411acf49449270aa8a27ac4173
Autor:
Iart Luca Shytaj, Mohamed Fares, Lara Gallucci, Bojana Lucic, Mahmoud M. Tolba, Liv Zimmermann, Julia M. Adler, Na Xing, Judith Bushe, Achim D. Gruber, Ina Ambiel, Ahmed Taha Ayoub, Mirko Cortese, Christopher J. Neufeldt, Bettina Stolp, Mohamed Hossam Sobhy, Moustafa Fathy, Min Zhao, Vibor Laketa, Ricardo Sobhie Diaz, Richard E. Sutton, Petr Chlanda, Steeve Boulant, Ralf Bartenschlager, Megan L. Stanifer, Oliver T. Fackler, Jakob Trimpert, Andrea Savarino, Marina Lusic
Publikováno v:
mBio, Vol 13, Iss 2 (2022)
ABSTRACT Combinations of direct-acting antivirals are needed to minimize drug resistance mutations and stably suppress replication of RNA viruses. Currently, there are limited therapeutic options against the severe acute respiratory syndrome coronavi
Externí odkaz:
https://doaj.org/article/30bf4bc23be645f7a9bdfa7dd16e08e5
Autor:
Steffen Klein, Mirko Cortese, Sophie L. Winter, Moritz Wachsmuth-Melm, Christopher J. Neufeldt, Berati Cerikan, Megan L. Stanifer, Steeve Boulant, Ralf Bartenschlager, Petr Chlanda
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Here the authors visualize SARS-CoV-2 infected cells by in situ cryo-electron tomography, delineating the structural organization and conformational changes that occur during virus replication and budding; and provide insight into vRNP architecture a
Externí odkaz:
https://doaj.org/article/7a032aa67d8d4439ad792070dcdf9862
Autor:
Sophie L Winter, Gonen Golani, Fabio Lolicato, Melina Vallbracht, Keerthihan Thiyagarajah, Samy Sid Ahmed, Christian Lüchtenborg, Oliver T Fackler, Britta Brügger, Thomas Hoenen, Walter Nickel, Ulrich S Schwarz, Petr Chlanda
Ebola viruses (EBOVs) assemble into filamentous virions, whose shape and stability are determined by the matrix viral protein 40 (VP40). Virus entry into host cells occurs via membrane fusion in late endosomes; however, the mechanism of how the remar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ea7e1aaee4895820541f871cf38e841
http://hdl.handle.net/10138/358472
http://hdl.handle.net/10138/358472
Autor:
Sophie L. Winter, Gonen Golani, Fabio Lolicato, Melina Vallbracht, Keerthihan Thiyagarajah, Samy Sid Ahmed, Christian Luechtenborg, Oliver T Fackler, Britta Bruegger, Thomas Hoenen, Walter Nickel, Ulrich S Schwarz, Petr Chlanda
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bee6cb1a457c743c523741d44f1a9e4a
https://doi.org/10.15252/rc.2023198189
https://doi.org/10.15252/rc.2023198189
Autor:
Steffen Klein, Thorsten G. Müller, Dina Khalid, Vera Sonntag-Buck, Anke-Mareil Heuser, Bärbel Glass, Matthias Meurer, Ivonne Morales, Angelika Schillak, Andrew Freistaedter, Ina Ambiel, Sophie L. Winter, Liv Zimmermann, Tamara Naumoska, Felix Bubeck, Daniel Kirrmaier, Stephanie Ullrich, Isabel Barreto Miranda, Simon Anders, Dirk Grimm, Paul Schnitzler, Michael Knop, Hans-Georg Kräusslich, Viet Loan Dao Thi, Kathleen Börner, Petr Chlanda
Publikováno v:
Viruses, Vol 12, Iss 8, p 863 (2020)
Rapid large-scale testing is essential for controlling the ongoing pandemic of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The standard diagnostic pipeline for testing SARS-CoV-2 presence in patients with an ongoing infection is pre
Externí odkaz:
https://doaj.org/article/ecb4e0dd8f1f4504be4719959baa1d69
Autor:
Liv Zimmermann, Xiaohan Zhao, Jana Makroczyova, Moritz Wachsmuth-Melm, Vibhu Prasad, Ralf Bartenschlager, Petr Chlanda
Coronavirus replication is associated with the remodeling of cellular membranes resulting in the formation of double-membrane vesicles (DMVs). Recently, a pore spanning DMV was identified as a putative portal for viral RNA transcription and replicati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7590abd4eed6721c7375e85f9d66a452
https://doi.org/10.1101/2022.10.21.513196
https://doi.org/10.1101/2022.10.21.513196