Zobrazeno 1 - 10
of 160
pro vyhledávání: '"Petr, Broz"'
Autor:
Marketa Wayhelova, Vladimira Vallova, Petr Broz, Aneta Mikulasova, Jan Smetana, Hana Dynkova Filkova, Dominika Machackova, Kristina Handzusova, Renata Gaillyova, Petr Kuglik
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 19, Iss 1, Pp 1-12 (2024)
Abstract Background Neurodevelopmental disorders (NDDs) and/or associated multiple congenital abnormalities (MCAs) represent a genetically heterogeneous group of conditions with an adverse prognosis for the quality of intellectual and social abilitie
Externí odkaz:
https://doaj.org/article/46268ac87d8b4810be2aceadfdb01208
Autor:
Kateryna Shkarina, Petr Broz
Publikováno v:
Bio-Protocol, Vol 13, Iss 14 (2023)
Regulated cell death plays a key role in immunity, development, and homeostasis, but is also associated with a number of pathologies such as autoinflammatory and neurodegenerative diseases and cancer. However, despite the extensive mechanistic resear
Externí odkaz:
https://doaj.org/article/4f6b123bb098461c9e56e1483faa7545
Autor:
Eva Hasel de Carvalho, Shivani S Dharmadhikari, Kateryna Shkarina, Jingwei Rachel Xiong, Bruno Reversade, Petr Broz, Maria Leptin
Publikováno v:
eLife, Vol 12 (2023)
The inflammasome is a conserved structure for the intracellular detection of danger or pathogen signals. As a large intracellular multiprotein signaling platform, it activates downstream effectors that initiate a rapid necrotic programmed cell death
Externí odkaz:
https://doaj.org/article/5a6d7fc847d3413f978e958162dcd43c
Publikováno v:
mBio, Vol 14, Iss 3 (2023)
Externí odkaz:
https://doaj.org/article/d6efffbca479431f8dd37fb3a49d5c3e
Autor:
Sarah Huot-Marchand, Mégane Nascimento, Elodie Culerier, Mélissa Bourenane, Florence Savigny, Corinne Panek, Cindy Serdjebi, Marc Le Bert, Valérie F. J. Quesniaux, Bernhard Ryffel, Petr Broz, Nicolas Riteau, Aurélie Gombault, Isabelle Couillin
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Chronic pulmonary inflammation and chronic obstructive pulmonary disease (COPD) are major health issues largely due to air pollution and cigarette smoke (CS) exposure. The role of the innate receptor NLRP3 (nucleotide-binding domain and leucine-rich
Externí odkaz:
https://doaj.org/article/6d26fc733ad047d9ac5a9f202429cc1e
Akademický článek
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Autor:
Adela Misove, Ales Vicha, Petr Broz, Katerina Vanova, David Sumerauer, Lucie Stolova, Lucie Sramkova, Miroslav Koblizek, Josef Zamecnik, Martin Kyncl, Zuzana Holubova, Petr Liby, Jakub Taborsky, Vladimir Benes, Ivana Pernikova, David T. W. Jones, Martin Sill, Terezia Stancokova, Lenka Krskova, Michal Zapotocky
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-2 (2022)
Externí odkaz:
https://doaj.org/article/aa30d2b2aa7f4076953840826fa95a6d
Publikováno v:
Pediatric Blood & Cancer; Aug2024, Vol. 71 Issue 8, p1-3, 3p
Autor:
José Carlos Santos, Dave Boucher, Larisa Kapinos Schneider, Benjamin Demarco, Marisa Dilucca, Kateryna Shkarina, Rosalie Heilig, Kaiwen W. Chen, Roderick Y. H. Lim, Petr Broz
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Detection of LPS derived from Gram-negative bacteria by innate immune receptors is a critical step in the host response. Here Santos and colleagues show human GBP1 binds to LPS resulting in non-canonical inflammasome activation.
Externí odkaz:
https://doaj.org/article/6cea1f719e794133aac06f44406b21f2
Autor:
Jan Smetana, Vladimira Vallova, Marketa Wayhelova, Eva Hladilkova, Hana Filkova, Vera Horinova, Petr Broz, Aneta Mikulasova, Renata Gaillyova, Petr Kuglík
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Alport syndrome with intellectual disability (ATS-ID, AMME complex; OMIM #300194) is an X-linked contiguous gene deletion syndrome associated with an Xq22.3 locus mainly characterized by hematuria, renal failure, hearing loss/deafness, neurodevelopme
Externí odkaz:
https://doaj.org/article/553c39dc21554bb8bf291f2161880eb2