Post-exposure lopinavir-ritonavir prophylaxis versus surveillance for individuals exposed to SARS-CoV-2: the COPEP pragmatic open-label, cluster randomized trial

Autor: Labhardt, N. D., Smit, M., Petignat, I., Perneger, T., Marinosci, A., Ustero, P., Diniz Ribeiro, M. P., Ragozzino, S., Nicoletti, G. J., Faré, P. B., Andrey, D. O., Jacquerioz, F., Lebowitz, D., Agoritsas, T., Meyer, B., Spechbach, H., Salamun, J., Guessous, I., Chappuis, F., Kaiser, L., Decosterd, L. A., Grinsztejn, B., Bernasconi, E., Cardoso, S. W., Calmy, A., Team, Ftcs

Publikováno v: EClinicalMedicine

Background Since the beginning of the COVID-19 pandemic, no direct antiviral treatment is effective as post-exposure prophylaxis (PEP). Lopinavir/ritonavir (LPV/r) was repurposed as a potential PEP agent against COVID-19. Methods We conducted a pragm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75eb3061b0423cb85801c5e6c2373516
https://edoc.unibas.ch/89184/

Guide pratique 2013 de prévention et de traitement des infections en établissement médico-social

Autor: Beffa, F., Bizzozzero, T., Koffi, M., Allenbach, N., Annen Joerg, P., Taran, P., Monod, S., Eyer, S., Rodondi, A., Major, K., Doser, N., Jabri, A., Clerc, O., Roosevelt, A., Linder, S., Nahimana Tessemo, I., Petignat, I.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1900::8b230ea4dcb1f1f20693e16b919dd77b
https://serval.unil.ch/resource/serval:BIB_FCC47DFD1DCC.P001/REF.pdf

Post-exposure Lopinavir-Ritonavir Prophylaxis versus Surveillance for Individuals Exposed to SARS-CoV-2: The COPEP Pragmatic Open-Label, Cluster Randomized Trial.

Autor: Labhardt ND; Department of Infectious Diseases and Hospital Epidemiology, University of Basel, Basel, Switzerland.; Department of Medicine, Swiss Tropical and Public Health Institute, Basel, Switzerland.; University of Basel, Basel, Switzerland., Smit M; Division of Infectious Diseases, Geneva University Hospitals, Faculty of Medicine, Geneva, Switzerland.; Department of Medicine, Faculty of Medicine, University of Geneva, Geneva, Switzerland., Petignat I; Division of Infectious Diseases, Geneva University Hospitals, Faculty of Medicine, Geneva, Switzerland., Perneger T; Division of Clinical Epidemiology, Geneva University Hospitals, Geneva, Switzerland., Marinosci A; Division of Infectious Diseases, Geneva University Hospitals, Faculty of Medicine, Geneva, Switzerland., Ustero P; Division of Infectious Diseases, Geneva University Hospitals, Faculty of Medicine, Geneva, Switzerland., Diniz Ribeiro MP; Lab. De Pesquisa Clinica DST/AIDS, Instituto Nacional de Infectologia Evandro Chagas, Fiocruz, Rio de Janeiro, Brazil., Ragozzino S; Department of Infectious Diseases and Hospital Epidemiology, University of Basel, Basel, Switzerland., Nicoletti GJ; Department of Infectious Diseases and Hospital Epidemiology, University of Basel, Basel, Switzerland.; Department of Medicine, Swiss Tropical and Public Health Institute, Basel, Switzerland., Faré PB; Division of Infectious Diseases, Ospedale Regionale di Lugano and Faculty of Medicine, University of Southern Switzerland, Lugano, Switzerland., Andrey DO; Division of Infectious Diseases, Geneva University Hospitals, Faculty of Medicine, Geneva, Switzerland.; Division of Laboratory Medicine, Diagnostic Department, Geneva University Hospitals, Geneva, Switzerland., Jacquerioz F; Division and Department of Primary Care, Geneva University Hospitals, Geneva, Switzerland., Lebowitz D; Infection Control Program, Geneva University Hospitals, Geneva, Switzerland., Agoritsas T; Division of General Internal Medicine, Geneva University Hospital, Geneva, Switzerland.; Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada., Meyer B; Centre for Vaccinology, Department of Pathology and Immunology, University of Geneva, Geneva, Switzerland., Spechbach H; Division and Department of Primary Care, Geneva University Hospitals, Geneva, Switzerland., Salamun J; Division and Department of Primary Care, Geneva University Hospitals, Geneva, Switzerland., Guessous I; Division and Department of Primary Care, Geneva University Hospitals, Geneva, Switzerland., Chappuis F; Division and Department of Primary Care, Geneva University Hospitals, Geneva, Switzerland., Kaiser L; Division of Infectious Diseases, Geneva University Hospitals, Faculty of Medicine, Geneva, Switzerland.; Geneva Centre for Emerging Viral Diseases, Geneva University Hospitals, Geneva, Switzerland., Decosterd LA; Laboratory of Clinical Pharmacology, University of Lausanne, Lausanne, Switzerland., Grinsztejn B; Lab. De Pesquisa Clinica DST/AIDS, Instituto Nacional de Infectologia Evandro Chagas, Fiocruz, Rio de Janeiro, Brazil., Bernasconi E; Division of Infectious Diseases, Ospedale Regionale di Lugano and Faculty of Medicine, University of Southern Switzerland, Lugano, Switzerland., Cardoso SW; Lab. De Pesquisa Clinica DST/AIDS, Instituto Nacional de Infectologia Evandro Chagas, Fiocruz, Rio de Janeiro, Brazil., Calmy A; Division of Infectious Diseases, Geneva University Hospitals, Faculty of Medicine, Geneva, Switzerland.; Department of Medicine, Faculty of Medicine, University of Geneva, Geneva, Switzerland., Team FTCS; Department of Infectious Diseases and Hospital Epidemiology, University of Basel, Basel, Switzerland.; Division of Infectious Diseases, Geneva University Hospitals, Faculty of Medicine, Geneva, Switzerland.; Lab. De Pesquisa Clinica DST/AIDS, Instituto Nacional de Infectologia Evandro Chagas, Fiocruz, Rio de Janeiro, Brazil.; Division of Infectious Diseases, Ospedale Regionale di Lugano and Faculty of Medicine, University of Southern Switzerland, Lugano, Switzerland.

Publikováno v: EClinicalMedicine [EClinicalMedicine] 2021 Dec; Vol. 42, pp. 101188. Date of Electronic Publication: 2021 Nov 06.