Zobrazeno 1 - 10
of 169
pro vyhledávání: '"Petes, T D"'
Autor:
Greenwell, P. W., Petes, T. D., Gawel, M., Dominska, M., Hazkani-Covo, E., Bloom, K., Song, W.
Dicentric chromosomes undergo breakage in mitosis, resulting in chromosome deletions, duplications, and translocations. In this study, we map chromosome break sites of dicentrics in Saccharomyces cerevisiae by a mitotic recombination assay. The assay
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::decfc6de4983c26e185b7d7958216b12
Autor:
Song, W., Malc, E., Petes, T. D., Greenwell, P. W., Zhang, H., Puccia, C. M., Zeidler, A. F. B., Mieczkowski, P. A., Argueso, J. L.
The increasing ability to sequence and compare multiple individual genomes within a species has highlighted the fact that copy-number variation (CNV) is a substantial and underappreciated source of genetic diversity. Chromosome-scale mutations occur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee7733ca144fd4ef77069cb4d092ce04
Autor:
Degtyareva, N P, Greenwell, P, Hofmann, E R, Hengartner, M O, Zhang, L, Culotti, J G, Petes, T D
Mismatch repair genes are important in maintaining the fidelity of DNA replication. To determine the function of the Caenorhabditis elegans homologue of the MSH2 mismatch repair gene (msh-2), we isolated a strain of C. elegans with an insertion of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55db79fa453489bc3d1b08f5d1e503b7
Autor:
Greenwell, P. W., St. Charles, J., Andersen, S. L., Hazkani-Covo, E., Mieczkowski, P., Malc, E., Yin, Y., Petes, T. D., Dietrich, F. S.
In diploid eukaryotes, repair of double-stranded DNA breaks by homologous recombination often leads to loss of heterozygosity (LOH). Most previous studies of mitotic recombination in Saccharomyces cerevisiae have focused on a single chromosome or a s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a869b9ba27fb9a51821fc386f5db5994
Autor:
Nag, D K, Petes, T D
Publikováno v:
Molecular and Cellular Biology. 13:2324-2331
We describe a general physical method for detecting the heteroduplex DNA that is formed as an intermediate in meiotic recombination in the yeast Saccharomyces cerevisiae. We use this method to study the kinetic relationship between the formation of h
The mismatch repair (MMR) system is critical not only for the repair of DNA replication errors, but also for the regulation of mitotic and meiotic recombination processes. In a manner analogous to its ability to remove replication errors, the MMR sys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da5f43c51d6756767b691d510e55ff6d
Autor:
Petes, T D, Nag, D K
Publikováno v:
Molecular and Cellular Biology. 10:4420-4423
In Saccharomyces cerevisiae, recombination events occurring between allelic genes located on homologous chromosomes are often associated with heteroduplex formation. We found that recombination events between repeated genes on nonhomologous chromosom
In eukaryotes, meiotic recombination events are distributed nonrandomly in the genome, with certain regions having high levels of recombination (hotspots) and others having low levels (coldspots). Species with similar DNA sequences (for example, chim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de7fc16bf67364acee2e66ba0f5e2bbb
In the yeast Saccharomyces cerevisiae, certain genomic regions have very high levels of meiotic recombination (hot spots). The hot spot activity associated with the HIS4 gene requires the Bas1p transcription factor. To determine whether this relation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6bd36fb8561926f090caef82d9cb2331
Autor:
Petes, T. D., Barbera, M. A.
We developed a system that allows the selection of the reciprocal products resulting from spontaneous mitotic cross-overs in the yeast Saccharomyces cerevisiae. A number of other types of genetic events, including chromosome loss, can be monitored wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8732fb029ab9b45a21bd7b23217c1929