Candida antarctica lipase B performance in organic solvent at varying water activities studied by molecular dynamics simulations

Autor: Tjørnelund, Helena D., Vind, Jesper, Brask, Jesper, Woodley, John M., Peters, Günther H.J.

Publikováno v: In Computational and Structural Biotechnology Journal 2023 21:5451-5462

Investigation of the pH-dependent aggregation mechanisms of GCSF using low resolution protein characterization techniques and advanced molecular dynamics simulations

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Publikováno v: In Computational and Structural Biotechnology Journal 2022 20:1439-1455

The catalytic acid-base in GH109 resides in a conserved GGHGG loop and allows for comparable α-retaining and β-inverting activity in an N-acetylgalactosaminidase from Akkermansia muciniphila

Autor: Teze, David, Shuoker, Bashar, Chaberski, Evan Kirk, Kunstmann, Sonja, Fredslund, Folmer, Nielsen, Tine Sofie, Stender, Emil G. P., Peters, Günther H.J., Nordberg Karlsson, Eva, Welner, Ditte Hededam, Abou Hachem, Maher

Publikováno v: Teze, D, Shuoker, B, Chaberski, E K, Kunstmann, S, Fredslund, F, Nielsen, T S, Stender, E G P, Peters, G H J, Nordberg Karlsson, E, Welner, D H & Abou Hachem, M 2020, ' The catalytic acid-base in GH109 resides in a conserved GGHGG loop and allows for comparable α-retaining and β-inverting activity in an N-acetylgalactosaminidase from Akkermansia muciniphila ', A C S Catalysis, vol. 10, pp. 3809-3819 . https://doi.org/10.26434/chemrxiv.9989102.v1, https://doi.org/10.1021/acscatal.9b04474

Enzymes active on glycosidic bonds are defined according to the stereochemistry of both substrates and products of the reactions they catalyse. The CAZy classification further assigns these enzymes into sequence-based families sharing a common stereo

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https://orbit.dtu.dk/en/publications/2e1d692d-29a2-445b-b45d-c201cf19f764

Study of the interaction between a novel, protein-stabilizing dipeptide and Interferon-alpha-2a by construction of a Markov state model from molecular dynamics simulations.

Autor: Tosstorff, Andreas¹ (AUTHOR) andreas.tosstorff@cup.uni-muenchen.de, Peters, Günther H.J.² (AUTHOR), Winter, Gerhard¹ (AUTHOR)

Publikováno v: European Journal of Pharmaceutics & Biopharmaceutics. Apr2020, Vol. 149, p105-112. 8p.

The influence of different linker modifications on the catalytic activity and cellulose affinity of cellobiohydrolase Cel7A from Hypocrea jecorina.

Autor: Badino, Silke Flindt, Bathke, Jenny Kim, Sørensen, Trine Holst, Windahl, Michael Skovbo, Jensen, Kenneth, Peters, Günther H.J., Borch, Kim, Westh, Peter

Publikováno v: PEDS: Protein Engineering, Design & Selection; Jul2017, Vol. 30 Issue 7, p495-501, 7p