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pro vyhledávání: '"Peter-Michael Blohm"'
Autor:
Armin Walser, Silke Herok, Uwe Heinelt, Peter-Michael Blohm, Hans Matter, Detlev Schneider, Volker Brachvogel, Petra Lönze, Alexander Liesum, Elisabeth Defossa, Andrea Müller, Herman Schreuder, Peter Wildgoose, Fahad Al-Obeidi
Publikováno v:
Journal of Medicinal Chemistry. 45:2749-2769
A series of 138 nonchiral 3-amidinobenzyl-1H-indole-2-carboxamides and analogues as inhibitors of the blood coagulation enzyme factor Xa (fXa) were designed, synthesized, and investigated by X-ray structure analysis and 3D quantitative structure-acti