Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Peter van der Geer"'
Autor:
Barbara Hayes, Peter van der Geer
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 11, p 9214 (2023)
STS-1 and STS-2 form a small family of proteins that are involved in the regulation of signal transduction by protein–tyrosine kinases. Both proteins are composed of a UBA domain, an esterase domain, an SH3 domain, and a PGM domain. They use their
Externí odkaz:
https://doaj.org/article/bf7f7f3d41974465b17f1e992fcbaabe
Publikováno v:
Biochemical and Biophysical Research Communications. 490:1334-1339
ShcA is a cytoplasmic signaling protein that supports signal transduction by receptor protein-tyrosine kinases by providing auxiliary tyrosine phosphorylation sites that engage additional signaling proteins. The principal binding partner for tyrosine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::581e3c0de5515664f5673dce1953d0a8
https://doi.org/10.1016/j.bbrc.2017.07.024
https://doi.org/10.1016/j.bbrc.2017.07.024
Autor:
Anne N. Murphy, Alexander Y. Andreyev, Sandra E. Wiley, Jack E. Dixon, Melvin I. Simon, Robert Karisch, Peter van der Geer, Ting Fen Tsai, Ajit S. Divakaruni, Benjamin G. Neel, Estelle A. Wall, Yi Fan Chen, Guy Perkins
Publikováno v:
EMBO Molecular Medicine
Miner1 is a redox-active 2Fe2S cluster protein. Mutations in Miner1 result in Wolfram Syndrome, a metabolic disease associated with diabetes, blindness, deafness, and a shortened lifespan. Embryonic fibroblasts from Miner1(-/-) mice displayed ER stre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::567d451260cd0d747e66f2f4757f5484
https://doi.org/10.1002/emmm.201201429
https://doi.org/10.1002/emmm.201201429
Autor:
Gina N. Betts, Majid Ghassemian, Miklos Guttman, Peter van der Geer, Elizabeth A. Komives, Helen Barnes
Publikováno v:
PROTEOMICS. 9:5016-5028
The low density lipoprotein receptor-related protein 1 (LRP1) mediates internalization of a large number of proteins and protein-lipid complexes and is widely implicated in Alzheimer's disease. The cytoplasmic domain of LRP1 (LRP1-CT) can be phosphor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42178cf3d4c6771ac5163e8e58100a27
https://doi.org/10.1002/pmic.200900457
https://doi.org/10.1002/pmic.200900457
Autor:
Peter van der Geer, Gary Glenn
Publikováno v:
FEBS Letters. 581:5377-5381
The CSF-1 receptor is a protein-tyrosine kinase that has been shown to undergo regulated intramembrane proteolysis, or RIPping. Here, we have compared receptor downregulation and RIPping in response to CSF-1 and TPA. Our studies show that CSF-1 is a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c4356a15ea7f2f53e6ac5d072fe9d35
https://doi.org/10.1016/j.febslet.2007.10.031
https://doi.org/10.1016/j.febslet.2007.10.031
Publikováno v:
Biochemistry & Pharmacology: Open Access.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::57fecdd7d8a43d0acaddf8097d5b76cb
https://doi.org/10.4172/2167-0501.1000169
https://doi.org/10.4172/2167-0501.1000169
Autor:
Jeremy Copp, Peter van der Geer, Kevin Wilhelmsen, Ross C. Hoffman, Gary Glenn, Philip W. Tucker
Publikováno v:
Molecular & Cellular Proteomics. 3:887-895
Protein-tyrosine kinases are known regulators of cell division that have been implicated in the onset of a variety of malignancies. They act through cellular signaling proteins that bind to specific autophosphorylation sites. To find out whether thes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a19adb5214346518a26f08973a64ed3c
https://doi.org/10.1074/mcp.m400062-mcp200
https://doi.org/10.1074/mcp.m400062-mcp200
Autor:
Michael Marino, Tara Chapman, Partho Ghosh, Manidipa Banerjee, T. Danka Vuga, T. Jeremy Copp, Peter van der Geer
Publikováno v:
Molecular Microbiology. 52:257-271
The Listeria monocytogenes protein InlB promotes intracellular invasion by activating the receptor tyrosine kinase Met. Earlier studies have indicated that the LRR fragment of InlB is sufficient for Met activation, but we show that this is not the ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4eb850c67744040e77796cf64b838fde
https://doi.org/10.1111/j.1365-2958.2003.03968.x
https://doi.org/10.1111/j.1365-2958.2003.03968.x
Publikováno v:
Oncogene. 22:3589-3597
We recently observed that the LDL receptor-related protein 1 (LRP-1) is tyrosine phosphorylated in v-Src-transformed cells. Using a GST-fusion protein containing the cytoplasmic domain of LRP-1, we show that LRP-1 is a direct substrate for v-Src in v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bf390dd01f130c759b648d2e55b99aa
https://doi.org/10.1038/sj.onc.1206504
https://doi.org/10.1038/sj.onc.1206504
Publikováno v:
Journal of Biological Chemistry. 278:7783-7789
Internalin B (InlB) is a protein present on the surface of Listeria monocytogenes that mediates bacterial entry into mammalian cells. It is thought that InlB acts by binding directly to the hepatocyte growth factor (HGF) receptor, present on the surf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4602579a8b30d058c3778e2e4bd5d579
https://doi.org/10.1074/jbc.m211666200
https://doi.org/10.1074/jbc.m211666200