Výsledky vyhledávání - "Peter van Lent"

Akademický článek

S100A8/A9-alarmin promotes local myeloid-derived suppressor cell activation restricting severe autoimmune arthritis

Autor: Meike von Wulffen, Veronika Luehrmann, Stefanie Robeck, Antonella Russo, Lena Fischer-Riepe, Martijn van den Bosch, Peter van Lent, Karin Loser, Dmitry I. Gabrilovich, Sven Hermann, Johannes Roth, Thomas Vogl

Publikováno v: Cell Reports, Vol 42, Iss 8, Pp 113006- (2023)

Summary: Immune-suppressive effects of myeloid-derived suppressor cells (MDSCs) are well characterized during anti-tumor immunity. The complex mechanisms promoting MDSC development and their regulatory effects during autoimmune diseases are less unde

Externí odkaz: https://doaj.org/article/8b2865b65c60489d869aa0d309545a05

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Akademický článek

Unraveling SSc Pathophysiology; The Myofibroblast

Autor: Arjan van Caam, Madelon Vonk, Frank van den Hoogen, Peter van Lent, Peter van der Kraan

Publikováno v: Frontiers in Immunology, Vol 9 (2018)

Systemic sclerosis (SSc) is a severe auto-immune disease, characterized by vasculopathy and fibrosis of connective tissues. SSc has a high morbidity and mortality and unfortunately no disease modifying therapy is currently available. A key cell in th

Externí odkaz: https://doaj.org/article/f8197adee38842239358b9a279a9a59e

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Akademický článek

Survival and biodistribution of xenogenic adipose mesenchymal stem cells is not affected by the degree of inflammation in arthritis.

Autor: Karine Toupet, Marie Maumus, Patricia Luz-Crawford, Eleuterio Lombardo, Juan Lopez-Belmonte, Peter van Lent, Marina I Garin, Wim van den Berg, Wilfried Dalemans, Christian Jorgensen, Danièle Noël

Publikováno v: PLoS ONE, Vol 10, Iss 1, p e0114962 (2015)

BACKGROUND:Application of mesenchymal stem/stromal cells (MSCs) in treating different disorders, in particular osteo-articular diseases, is currently under investigation. We have already documented the safety of administrating human adipose tissue-de

Externí odkaz: https://doaj.org/article/ebbe932413f742739b803d6268447fed

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Akademický článek

Pathogenic role of basic calcium phosphate crystals in destructive arthropathies.

Autor: Hang-Korng Ea, Véronique Chobaz, Christelle Nguyen, Sonia Nasi, Peter van Lent, Michel Daudon, Arnaud Dessombz, Dominique Bazin, Geraldine McCarthy, Brigitte Jolles-Haeberli, Annette Ives, Daniel Van Linthoudt, Alexander So, Frédéric Lioté, Nathalie Busso

Publikováno v: PLoS ONE, Vol 8, Iss 2, p e57352 (2013)

Backgroundbasic calcium phosphate (BCP) crystals are commonly found in osteoarthritis (OA) and are associated with cartilage destruction. BCP crystals induce in vitro catabolic responses with the production of metalloproteases and inflammatory cytoki

Externí odkaz: https://doaj.org/article/3a2f0b596c8545f693ef36693ec568e1

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