Výsledky vyhledávání - "Peter in't Veld"

Akademický článek

The β2-adrenergic receptor in the apical membrane of intestinal enterocytes senses sugars to stimulate glucose uptake from the gut

Autor: Frederik Paulussen, Chetan P. Kulkarni, Frank Stolz, Eveline Lescrinier, Stijn De Graeve, Suzan Lambin, Arnaud Marchand, Patrick Chaltin, Peter In't Veld, Joseph Mebis, Jan Tavernier, Patrick Van Dijck, Walter Luyten, Johan M. Thevelein

Publikováno v: Frontiers in Cell and Developmental Biology, Vol 10 (2023)

The presence of sugar in the gut causes induction of SGLT1, the sodium/glucose cotransporter in intestinal epithelial cells (enterocytes), and this is accompanied by stimulation of sugar absorption. Sugar sensing was suggested to involve a G-protein

Externí odkaz: https://doaj.org/article/4ae53f76b62b4a54b8ca432078659319

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Akademický článek

Normal Pregnancy-Induced Islet Beta Cell Proliferation in Mouse Models That Are Deficient in Serotonin-Signaling

Autor: Lotte Goyvaerts, Anica Schraenen, Katleen Lemaire, Peter in’t Veld, Ilse Smolders, Luc Maroteaux, Frans Schuit

Publikováno v: International Journal of Molecular Sciences, Vol 23, Iss 24, p 15816 (2022)

During mouse pregnancy placental lactogens stimulate prolactin receptors on pancreatic islet beta cells to induce expression of the tryptophan hydroxylase Tph1, resulting in the synthesis and secretion of serotonin. Presently, the functional relevanc

Externí odkaz: https://doaj.org/article/d60cc7e1668e400c87f4bcb0bea68a3b

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Akademický článek

Pancreas and gallbladder agenesis in a newborn with semilobar holoprosencephaly, a case report

Autor: Robert Hilbrands, Kathelijn Keymolen, Alex Michotte, Miriam Marichal, Filip Cools, Anieta Goossens, Peter In’t Veld, Jean De Schepper, Andrew Hattersley, Harry Heimberg

Publikováno v: BMC Medical Genetics, Vol 18, Iss 1, Pp 1-5 (2017)

Abstract Background Pancreatic agenesis is an extremely rare cause of neonatal diabetes mellitus and has enabled the discovery of several key transcription factors essential for normal pancreas and beta cell development. Case presentation We report a

Externí odkaz: https://doaj.org/article/72e8bc1cb46346d1a9e49df337a4f3e0

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Akademický článek

Identification of Donor Origin and Condition of Transplanted Islets in Situ in the Liver of a Type 1 Diabetic Recipient

Autor: Cornelis R. Van Der Torren, Jessica S. Suwandi, Dahae Lee, Ernst-Jan T. Van't Wout, Gaby Duinkerken, Godelieve Swings, Arend Mulder, Frans H. J. Claas, Zhidong Ling, Pieter Gillard, Bart Keymeulen, Peter In't Veld, Bart O. Roep

Publikováno v: Cell Transplantation, Vol 26 (2017)

Transplantation of islet allografts into type 1 diabetic recipients usually requires multiple pancreas donors to achieve insulin independence. This adds to the challenges of immunological monitoring of islet transplantation currently relying on surro

Externí odkaz: https://doaj.org/article/4fc08ec296f34a08bf92a0beb0387133

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Akademický článek

Prolactin receptors and placental lactogen drive male mouse pancreatic islets to pregnancy-related mRNA changes.

Autor: Lotte Goyvaerts, Katleen Lemaire, Ingrid Arijs, Julien Auffret, Mikaela Granvik, Leentje Van Lommel, Nadine Binart, Peter in't Veld, Frans Schuit, Anica Schraenen

Publikováno v: PLoS ONE, Vol 10, Iss 3, p e0121868 (2015)

Pregnancy requires a higher functional beta cell mass and this is associated with profound changes in the gene expression profile of pancreatic islets. Taking Tph1 as a sensitive marker for pregnancy-related islet mRNA expression in female mice, we p

Externí odkaz: https://doaj.org/article/297f4ab4c6994561ada157a2f4790ef5

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Akademický článek

Poly-L-Lysine Induces Fibrosis on Alginate Microcapsules via the Induction of Cytokines

Autor: Berit L. Strand, Liv Ryan, Peter In't Veld, Bård Kulseng, Anne Mari Rokstad, Gudmund Skjåk-Bræk, Terje Espevik

Publikováno v: Cell Transplantation, Vol 10 (2001)

Alginate – poly-l-lysine (PLL) microcapsules can be used for transplantation of insulin-producing cells for treatment of type I diabetes. In this work we wanted to study the inflammatory reactions against implanted microcapsules due to PLL. We have

Externí odkaz: https://doaj.org/article/613f6690564e4829a953bb313115aa9b

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Data from Different Tumor Microenvironments Contain Functionally Distinct Subsets of Macrophages Derived from Ly6C(high) Monocytes

Autor: Jo A. Van Ginderachter, Patrick De Baetselier, Peter In't Veld, Daniel Pipeleers, Matthias Mack, Jan Van den Bossche, Geert Stangé, Martijn Baeten, Conny Gysemans, Damya Laoui, Kiavash Movahedi

Tumor-associated macrophages (TAM) form a major component of the tumor stroma. However, important concepts such as TAM heterogeneity and the nature of the monocytic TAM precursors remain speculative. Here, we show for the first time that mouse mammar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b372b280fb0a2cf626fd6745aa3c86b7
https://doi.org/10.1158/0008-5472.c.6500718

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Discovery and 3D imaging of a novel ΔNp63-expressing basal cell type in human pancreatic ducts with implications in disease

Publikováno v: Gut
Gut, BMJ Publishing Group, In press, ⟨10.1136/gutjnl-2020-322874⟩
Gut, In press, ⟨10.1136/gutjnl-2020-322874⟩
Gut, p. [1-13] (2021)

Objective: The aggressive basal-like molecular subtype of pancreatic ductal adenocarcinoma (PDAC) harbours a ΔNp63 (p40) gene expression signature reminiscent of a basal cell type. Distinct from other epithelia with basal tumours, ΔNp63+ basal cell

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b1753811ff45faa28755ff5c1e5e2cd
https://hal.archives-ouvertes.fr/hal-03314798/document

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