Zobrazeno 1 - 10
of 118
pro vyhledávání: '"Peter de Haan"'
Autor:
Peter de Haan
Publikováno v:
Journal of Affective Disorders Reports, Vol 12, Iss , Pp 100532- (2023)
Neurodegenerative and psychiatric diseases (NPDs) are associated with chronic or flaring brain inflammation and infiltrations of cytotoxic lymphocytes in the inflamed brain parts, causing mild to severe or even lethal brain damage. NPDs thus show fea
Externí odkaz:
https://doaj.org/article/1bf7673190994e788c67577f645d4bf0
Publikováno v:
Challenging Glass Conference Proceedings, Vol 8 (2022)
Among the environmental factors affecting glass weathering are humidity, exposure time, temperature, and the presence of pollutants in the atmosphere. Notwithstanding that the weathering produced depends on numerous factors, the important weathering
Externí odkaz:
https://doaj.org/article/584dcaf3f36149ac9ebc36810913b2cb
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 17, Iss 1, Pp 14-21 (2021)
Viruses have evolved to efficiently express their genes in host cells, which makes them ideally suited as gene delivery vectors for gene and immunotherapies. Replication competent (RC) viral vectors encoding foreign or self-proteins induce strong T-c
Externí odkaz:
https://doaj.org/article/7c77607ffd914eba917339b41397b390
Autor:
Xiaoxia Shi, Matthew Ryan Ykema, Jaco Hazenoot, Lysbeth ten Bloemendaal, Irene Mancini, Machteld Odijk, Peter de Haan, Piter J. Bosma
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 9, Iss , Pp 225-233 (2018)
Gene therapy has been shown to be a feasible approach to treat inherited disorders in vivo. Among the currently used viral vector systems, adeno-associated virus (AAV) vectors are the most advanced and have been applied in patients successfully. An i
Externí odkaz:
https://doaj.org/article/808dde88a3224fa88352b04ce933873e
Autor:
Nadia Cobo-Vuilleumier, Petra I. Lorenzo, Noelia García Rodríguez, Irene de Gracia Herrera Gómez, Esther Fuente-Martin, Livia López-Noriega, José Manuel Mellado-Gil, Silvana-Yanina Romero-Zerbo, Mathurin Baquié, Christian Claude Lachaud, Katja Stifter, German Perdomo, Marco Bugliani, Vincenzo De Tata, Domenico Bosco, Geraldine Parnaud, David Pozo, Abdelkrim Hmadcha, Javier P. Florido, Miguel G. Toscano, Peter de Haan, Kristina Schoonjans, Luis Sánchez Palazón, Piero Marchetti, Reinhold Schirmbeck, Alejandro Martín-Montalvo, Paolo Meda, Bernat Soria, Francisco-Javier Bermúdez-Silva, Luc St-Onge, Benoit R. Gauthier
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
Type 1 diabetes mellitus (T1DM) is characterized by beta cell loss because of an autoimmune attack. Here the authors show that an agonist for LRH-1/NR5A2, a nuclear receptor known to be protective against beta cell apoptosis, inhibits immune-mediated
Externí odkaz:
https://doaj.org/article/fbb9d971aff1451c95b83f3e8763290c
Autor:
Lucilla E. Overdijk, Bart M. P. Rademaker, Paul J. M. van Kesteren, Peter de Haan, Robert K. Riezebos, Oscar C. H. Haude
Publikováno v:
Trials, Vol 19, Iss 1, Pp 1-6 (2018)
Abstract Background Transcervical resection of myoma or endometrium is a safe, hysteroscopic, minimally invasive procedure. However, intravasation of distension fluid is a common phenomenon during these procedures. In a previous study we observed ven
Externí odkaz:
https://doaj.org/article/50ab947e7009458f832676b995fadce9
Autor:
Miguel G. Toscano, Jeroen van der Velden, Sybrand van der Werf, Machteld Odijk, Ana Roque, Rafael J. Camacho-Garcia, Irene G. Herrera-Gomez, Irene Mancini, Peter de Haan
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 6, Iss C, Pp 124-134 (2017)
Replication-defective (RD) recombinant simian virus 40 (SV40)-based gene delivery vectors hold a great potential for clinical applications because of their presumed non-immunogenicity and capacity to induce immune tolerance to the transgene products
Externí odkaz:
https://doaj.org/article/06c68bd3b6a94f5094f1b73b60f6b041
Autor:
Miguel G. Toscano, Peter de Haan
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Viruses efficiently transfer and express their genes in host cells and evolve to evade the host’s defense responses. These properties render them highly attractive for use as gene delivery vectors in vaccines, gene, and immunotherapies. Among the v
Externí odkaz:
https://doaj.org/article/d16032fe67804711998b62aa64020570
Autor:
Joost Haasnoot, Walter de Vries, Ernst-Jan Geutjes, Marcel Prins, Peter de Haan, Ben Berkhout
Publikováno v:
PLoS Pathogens, Vol 3, Iss 6, p e86 (2007)
RNA silencing or interference (RNAi) is a gene regulation mechanism in eukaryotes that controls cell differentiation and developmental processes via expression of microRNAs. RNAi also serves as an innate antiviral defence response in plants, nematode
Externí odkaz:
https://doaj.org/article/f60059b81c6f4c52938d6dfe9ce1e013
Publikováno v:
Human Vaccines & Immunotherapeutics
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Viruses have evolved to efficiently express their genes in host cells, which makes them ideally suited as gene delivery vectors for gene and immunotherapies. Replication competent (RC) viral vectors encoding foreign or self-proteins induce strong T-c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5120e9196b5c50baa78eeb9751c324ee
https://doi.org/10.1080/21645515.2020.1757989
https://doi.org/10.1080/21645515.2020.1757989