Zobrazeno 1 - 10
of 241
pro vyhledávání: '"Peter Zahradka"'
Autor:
Lisa A. Rodway, Samantha D. Pauls, Christopher D. Pascoe, Harold M. Aukema, Carla G. Taylor, Peter Zahradka
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 159, Iss , Pp 114167- (2023)
Background: Monocytes play a large role in chronic inflammatory conditions such as obesity, atherosclerosis and infection. Marine-derived omega-3 fatty acids such as docosahexaenoic acid (DHA) beneficially alter immune function and attenuate chronic
Externí odkaz:
https://doaj.org/article/bce20e9061b1407184bda7313dd018ed
Publikováno v:
Cell Communication and Signaling, Vol 19, Iss 1, Pp 1-29 (2021)
Abstract Background The calcium (Ca2+)/calmodulin (CAM)-activated kinase kinase 2 (CAMKK2)-signaling regulates several physiological processes, for example, glucose metabolism and energy homeostasis, underlying the pathogenesis of metabolic diseases.
Externí odkaz:
https://doaj.org/article/f7c2b19870634856b6087a994dd255a9
Autor:
Peter Zahradka, Carla G. Taylor, Leslee Tworek, Raissa Perrault, Sofia M’Seffar, Megha Murali, Tara Loader, Jeffrey T. Wigle
Publikováno v:
Biomolecules, Vol 13, Iss 1, p 30 (2022)
A decrease in the circulating levels of adiponectin in obesity increases the risk of metabolic complications, but the role of globular adiponectin, a truncated form produced by proteolytic cleavage, has not been defined. The objective of this investi
Externí odkaz:
https://doaj.org/article/e1a0cedcb9bc4de8ba833307be4ef5e9
Publikováno v:
BMC Cardiovascular Disorders, Vol 19, Iss 1, Pp 1-8 (2019)
Abstract Background Development of instruments capable of detecting early stage vascular disease has increased interest in employing arterial stiffness (e.g. pulse wave velocity (PWV), augmentation index (AIx)) and endothelial dysfunction (e.g. react
Externí odkaz:
https://doaj.org/article/dc233fb3d587471384c3fe091c9cb619
Publikováno v:
Cells, Vol 11, Iss 16, p 2478 (2022)
Endothelial cells regulate vascular homeostasis through the secretion of various paracrine molecules, including bioactive lipids, but little is known regarding the enzymes responsible for generating these lipids under either physiological or pathophy
Externí odkaz:
https://doaj.org/article/040463328f8743408458577a2906bb8c
Publikováno v:
PLoS ONE, Vol 13, Iss 5, p e0197613 (2018)
Consumption of different PUFAs (polyunsaturated fatty acids) can induce functional changes in blood vessels via endothelial cells, which interact with dietary factors in the circulation. The basement membrane that separates the endothelium from the s
Externí odkaz:
https://doaj.org/article/7f0bef50b29e413bafdff3d7e396e88a
Publikováno v:
Foods, Vol 7, Iss 8, p 129 (2018)
Pulses are nutrient-rich ingredients used as interventions in clinical trials to determine their effect on lowering blood lipids, which are risk factors for cardiovascular disease. Acceptability of these foods is critical for compliance by participan
Externí odkaz:
https://doaj.org/article/0e4154dc56734434bb65c85335378cab
Autor:
D. Dan Ramdath, Thomas M. S. Wolever, Yaw Chris Siow, Donna Ryland, Aileen Hawke, Carla Taylor, Peter Zahradka, Michel Aliani
Publikováno v:
Foods, Vol 7, Iss 5, p 76 (2018)
The consumption of pulses is associated with many health benefits. This study assessed post-prandial blood glucose response (PPBG) and the acceptability of food items containing green lentils. In human trials we: (i) defined processing methods (boili
Externí odkaz:
https://doaj.org/article/401977f08bc749b096b375cfc21ffd84
Publikováno v:
Journal of Obesity, Vol 2011 (2011)
Obesity rates are rapidly increasing worldwide and facilitate the development of many related disease states, such as cardiovascular disease, the metabolic syndrome, type 2 diabetes mellitus, and various types of cancer. Variation in metabolically im
Externí odkaz:
https://doaj.org/article/b09a23fa516147f28b225603f3aac629
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 9; Pages: 8346
Our laboratory previously reported that docosahexaenoic acid (DHA) differentially activates p38 mitogen-activated protein kinase (MAPK) in growing and quiescent human endothelial cells, which represent the dysfunctional and healthy states in vivo, re