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pro vyhledávání: '"Peter Zage"'
Autor:
Jennifer H. Foster, Eveline Barbieri, Linna Zhang, Kathleen A. Scorsone, Myrthala Moreno-Smith, Peter Zage, Terzah M. Horton
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 12, p 6565 (2021)
Pevonedistat is a neddylation inhibitor that blocks proteasomal degradation of cullin–RING ligase (CRL) proteins involved in the degradation of short-lived regulatory proteins, including those involved with cell-cycle regulation. We determined the
Externí odkaz:
https://doaj.org/article/674cae13e9fc4d49be3e1534645fd75f
Expression of the UBE4B ubiquitin ligase is strongly associated with neuroblastoma patient outcomes, but the functional roles of UBE4B in neuroblastoma pathogenesis are not known. We evaluated interactions of UBE4B with the E3 ubiquitin ligase ITCH/A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::218efebd8aaaee5985694357f9015fdc
https://doi.org/10.21203/rs.3.rs-2528139/v1
https://doi.org/10.21203/rs.3.rs-2528139/v1
Publikováno v:
Cancer Research. 83:6157-6157
Background: The ubiquitin-proteasome system (UPS) plays an essential role in post-translational modification of proteins to maintain proteostasis. Ubiquitination of target protein is coordinated by different enzymes, which add and link ubiquitin to e
Autor:
Ming, Zhang, Dolly, Aguilera, Chandra, Das, Hernan, Vasquez, Peter, Zage, Vidya, Gopalakrishnan, Johannes, Wolff
Publikováno v:
Anticancer research. 27(1A)
Cytotoxicity in cell culture is typically expressed as LC50 the concentration of a given agent which is lethal to 50% of the cells. This number is dependent on the incubation time with the agent. Previously, a two-term exponential model has been prop
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