Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Peter Y Wang"'
Publikováno v:
eLife, Vol 11 (2022)
MicroRNAs (miRNAs), in association with Argonaute (AGO) proteins, direct repression by pairing to sites within mRNAs. Compared to pairing preferences of the miRNA seed region (nucleotides 2–8), preferences of the miRNA 3′ region are poorly unders
Externí odkaz:
https://doaj.org/article/215a66502c1541fea6bb99de0d44e083
Autor:
Peter Y. Wang, David P. Bartel
Publikováno v:
BMC Bioinformatics, Vol 24, Iss 1, Pp 1-18 (2023)
Abstract Background One strategy for identifying targets of a regulatory factor is to perturb the factor and use high-throughput RNA sequencing to examine the consequences. However, distinguishing direct targets from secondary effects and experimenta
Externí odkaz:
https://doaj.org/article/a0013a31e2844e8cbc5b1f021bbf36e5
Autor:
Seiya Tajima, Yoon Seok Kim, Masahiro Fukuda, Eamon F.X. Byrne, Peter Y. Wang, Joseph M. Paggi, Koichiro E. Kishi, Charu Ramakrishnan, Syunki Takaramoto, Takashi Nagata, Masae Konno, Masahiro Sugiura, Kota Katayama, Toshiki E. Matsui, Keitaro Yamashita, Hisako Ikeda, Masatoshi Inoue, Hideki Kandori, Ron O. Dror, Keiichi Inoue, Karl Deisseroth, Hideaki E. Kato
SUMMARYThe KCR channelrhodopsins are recently-discovered light-gated ion channels with high K+selectivity, a property that has attracted broad attention among biologists– due to intense interest in creating novel inhibitory tools for optogenetics l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::838220718371e1a51e9fa3438f3392bc
https://doi.org/10.1101/2022.10.30.514430
https://doi.org/10.1101/2022.10.30.514430
Publikováno v:
eLife. 11
MicroRNAs (miRNAs), in association with Argonaute (AGO) proteins, direct repression by pairing to sites within mRNAs. Compared to pairing preferences of the miRNA seed region (nucleotides 2–8), preferences of the miRNA 3′ region are poorly unders
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee3583157adbc37c230eeab7611ba1ff
https://doi.org/10.7554/elife.69803
https://doi.org/10.7554/elife.69803
Autor:
Linlin Z. Fan, Doo Kyung Kim, Joshua H. Jennings, He Tian, Peter Y. Wang, Charu Ramakrishnan, Sawyer Randles, Yanjun Sun, Elina Thadhani, Yoon Seok Kim, Sean Quirin, Lisa Giocomo, Adam E. Cohen, Karl Deisseroth
Publikováno v:
Cell. 186:543-559.e19
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a67e0af52378552642453804c5597c9c
https://doi.org/10.1016/j.cell.2022.12.035
https://doi.org/10.1016/j.cell.2022.12.035
Autor:
Tsukasa Kusakizako, Mikihiro Shibata, Masahiro Fukuda, Tomoko Uemura, Koichiro E. Kishi, Joseph M. Paggi, Keitaro Yamashita, Hideaki E. Kato, Keiichi Inoue, Ron O. Dror, Tyler Benster, Takashi Nagata, So Iwata, Peter Y. Wang, Masae Konno, Toshiki E. Matsui, Charu Ramakrishnan, Kehong Liu, Masatoshi Inoue, Karl Deisseroth, Norimichi Nomura, Elina Thadhani, Yoon Seok Kim, Eamon F. X. Byrne, Osamu Nureki
SummaryChRmine1, a recently-discovered bacteriorhodopsin-like cation-conducting channelrhodopsin1, 2, exhibits puzzling properties (unusually-large photocurrents, exceptional red-shift in action spectrum, and extreme light-sensitivity) that have open
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c69d3b2fd614f297e2fb15ea3d4dfaf
https://doi.org/10.1101/2021.08.15.456392
https://doi.org/10.1101/2021.08.15.456392
SummaryThe convergent evolution of the fly and mouse olfactory system led us to ask whether the anatomic connectivity and functional logic of olfactory circuits would evolve in artificial neural networks trained to perform olfactory tasks. Artificial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d743d03aa24e1823e43d97aeb5d9322c
https://doi.org/10.1101/2021.04.15.439917
https://doi.org/10.1101/2021.04.15.439917
Publikováno v:
Proc Natl Acad Sci U S A
In cells, closely spaced microRNA (miRNA) target sites within a messenger RNA (mRNA) can act cooperatively, leading to more repression of the target mRNA than expected by independent action at each site. Using purified miRNA-Argonaute (AGO2) complexe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc11eecf7e75304bfcbfe50db81a7e25
https://pubmed.ncbi.nlm.nih.gov/32661162
https://pubmed.ncbi.nlm.nih.gov/32661162
Autor:
Koichiro E. Kishi, Yoon Seok Kim, Masahiro Fukuda, Masatoshi Inoue, Tsukasa Kusakizako, Peter Y. Wang, Charu Ramakrishnan, Eamon F.X. Byrne, Elina Thadhani, Joseph M. Paggi, Toshiki E. Matsui, Keitaro Yamashita, Takashi Nagata, Masae Konno, Sean Quirin, Maisie Lo, Tyler Benster, Tomoko Uemura, Kehong Liu, Mikihiro Shibata, Norimichi Nomura, So Iwata, Osamu Nureki, Ron O. Dror, Keiichi Inoue, Karl Deisseroth, Hideaki E. Kato
Publikováno v:
Cell
ChRmine, a recently discovered pump-like cation-conducting channelrhodopsin, exhibits puzzling properties (large photocurrents, red-shifted spectrum, and extreme light sensitivity) that have created new opportunities in optogenetics. ChRmine and its
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fe54c03c8b256bc5d24bfb804f19293
https://doi.org/10.1016/j.cell.2022.01.007
https://doi.org/10.1016/j.cell.2022.01.007