Temporal profile of the renal transcriptome of HIV-1 transgenic mice during disease progression.

Autor: Ying Fan, Chengguo Wei, Wenzhen Xiao, Weijia Zhang, Niansong Wang, Peter Y Chuang, John Cijiang He

Publikováno v: PLoS ONE, Vol 9, Iss 3, p e93019 (2014)

Profiling of temporal changes of gene expression in the same kidney over the course of renal disease progression is challenging because repeat renal biopsies are rarely indicated in clinical practice. Here, we profiled the temporal change in renal tr

Externí odkaz: https://doaj.org/article/550d4c84b21d4d939419ce3fac3268e6

Dysregulated nephrin in diabetic nephropathy of type 2 diabetes: a cross sectional study.

Autor: Belinda Jim, Mythili Ghanta, Andi Qipo, Ying Fan, Peter Y Chuang, Hillel W Cohen, Maria Abadi, David B Thomas, John Cijiang He

Publikováno v: PLoS ONE, Vol 7, Iss 5, p e36041 (2012)

Podocyte specific proteins are dysregulated in diabetic nephropathy, though the extent of their expression loss is not identical and may be subject to different regulatory factors. Quantifying the degree of loss may help identify the most useful prot

Externí odkaz: https://doaj.org/article/3da3122f02794f7aab154b0241efaeb4

Increased podocyte Sirtuin-1 function attenuates diabetic kidney injury

Autor: Lu Zhang, Guangyan Cai, Bohan Liu, Bhaskar C. Das, Quan Hong, Zhengzhe Li, Xiangmei Chen, Kyung Lee, Peter Y. Chuang, John Cijiang He

Publikováno v: Kidney International. 93:1330-1343

Podocyte injury and loss contribute to the progression of glomerular diseases, including diabetic kidney disease. We previously found that the glomerular expression of Sirtuin-1 (SIRT1) is reduced in human diabetic glomeruli and that the podocyte-spe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fe2f91e1024fd80b4557fc810a89b12
https://doi.org/10.1016/j.kint.2017.12.008

Retinoic acid improves nephrotoxic serum–induced glomerulonephritis through activation of podocyte retinoic acid receptor α

Autor: Yan Dai, Xiaoqiang Ding, Weijing Cai, Marcus J. Moeller, Stuart J. Shankland, Shuchita Sharma, Norbert B. Ghyselinck, Jeffrey Pippin, Ruijie Liu, Kyung Lee, John Cijiang He, Anqun Chen, Leyi Gu, David J. Salant, Fadi Salem, Peter Y. Chuang

Publikováno v: Kidney International
Kidney International, Nature Publishing Group, 2017, 92 (6), pp.1444-1457. ⟨10.1016/j.kint.2017.04.026⟩
Kidney International, 2017, 92 (6), pp.1444-1457. ⟨10.1016/j.kint.2017.04.026⟩

Proliferation of glomerular epithelial cells, including podocytes, is a key histologic feature of crescentic glomerulonephritis. We previously found that retinoic acid (RA) inhibits proliferation and induces differentiation of podocytes by activating

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91fc258a2364f2811cfb7836ffdcf0b7
https://hal.archives-ouvertes.fr/hal-02324133/document

Intronic locus determines SHROOM3 expression and potentiates renal allograft fibrosis

Autor: Chengguo Wei, Robert B. Colvin, Arjang Djamali, Jessica Overbey, Millagros Saminego, Ivy A. Rosales, Meng Ma, John Cijiang He, Huabao Xiong, Philip J. O'Connell, Christopher Woytovich, Zhengzi Yi, Zhengzhe Li, Wei Ding, Lorenzo Gallon, Rong Chen, Ilana Greene, Weijia Zhang, Bernd Schröppel, Madhav C. Menon, Y. Luan, Emilia Bagiella, Li Li, Peter Y. Chuang, Barbara Murphy

Publikováno v: Journal of Clinical Investigation. 125:208-221

Fibrosis underlies the loss of renal function in patients with chronic kidney disease (CKD) and in kidney transplant recipients with chronic allograft nephropathy (CAN). Here, we studied the effect of an intronic SNP in SHROOM3, which has previously

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff49aa4ea6bc0d4f10370a4da2a3c7c0
https://doi.org/10.1172/jci76902