Zobrazeno 1 - 10
of 354
pro vyhledávání: '"Peter X. Ma"'
Publikováno v:
Bone Research, Vol 12, Iss 1, Pp 1-21 (2024)
Abstract Bone and joint-related diseases, including osteoarthritis (OA), rheumatoid arthritis (RA), and bone tumors, pose significant health challenges due to their debilitating effects on the musculoskeletal system. 14-3-3 proteins, a family of cons
Externí odkaz:
https://doaj.org/article/d7c02ecbe0c740f28d45f977a5b23448
Publikováno v:
Bioactive Materials, Vol 43, Iss , Pp 98-113 (2025)
More than 500,000 bone grafting procedures are performed annually in the USA. Considering the significant limitations of available bone grafts, we previously invented a phase-separation technology to generate nanofibrous poly(l-lactic acid) (PLLA) sc
Externí odkaz:
https://doaj.org/article/46e9c485471a40f5bf6799192b79ca01
Publikováno v:
Materials Today Bio, Vol 28, Iss , Pp 101182- (2024)
Prosthesis-induced pathological calcification is a significant challenge in biomaterial applications and is often associated with various reconstructive medical procedures. It is uncertain whether the fibrous extracellular matrix (ECM) adjacent to bi
Externí odkaz:
https://doaj.org/article/1c73c09c8fe44a55b3028d7610a16bc4
Autor:
Kemao Xiu, Laura Saunders, Luan Wen, Jinxue Ruan, Ruonan Dong, Jun Song, Dongshan Yang, Jifeng Zhang, Jie Xu, Y. Eugene Chen, Peter X. Ma
Publikováno v:
Cells, Vol 12, Iss 1, p 156 (2022)
Gene editing nucleases such as CRISPR/Cas9 have enabled efficient and precise gene editing in vitro and hold promise of eventually achieving in vivo gene editing based therapy. However, a major challenge for their use is the lack of a safe and effect
Externí odkaz:
https://doaj.org/article/93602edda32c46029d7ed99e5661f88a
Publikováno v:
Polymers, Vol 14, Iss 17, p 3656 (2022)
Conventional direct pulp capping, such as calcium hydroxide (Ca(OH)2) or silicate products, usually induces an inflammatory reaction to provoke pulp regeneration. Phosphophoryn (PP) and dentin sialoprotein (DSP), the two most abundant non-collagenous
Externí odkaz:
https://doaj.org/article/bd57348a210e472193ca559963c9b1fc
Autor:
Meifeng Zhu, Wen Li, Xianhao Dong, Xingyu Yuan, Adam C. Midgley, Hong Chang, Yuhao Wang, Haoyu Wang, Kai Wang, Peter X. Ma, Hongjun Wang, Deling Kong
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Extracellular matrix (ECM) is an ideal scaffold for tissue engineering but tends to lack hierarchical structure. Here the authors implant sacrificial templates subcutaneously to build an organised ECM scaffold, and following template removal and dece
Externí odkaz:
https://doaj.org/article/8e0c5cbb395143ea97944ec1cd4410e7
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Osteoarthritis involves whole-joint tissue degeneration. Here, the authors show that miR-204 and miR-211 in mesenchymal joint cells regulate their proliferation, catabolic and osteogenic responses, and that disease progression is ameliorated by intra
Externí odkaz:
https://doaj.org/article/5aae4a0d105542e7914d2239eb10e034
Autor:
Shuo Tian, Ienglam Lei, Wenbin Gao, Liu Liu, Yijing Guo, Jeffery Creech, Todd J. Herron, Shaoxiang Xian, Peter X. Ma, Y. Eugene Chen, Yongqing Li, Hasan B. Alam, Zhong Wang
Publikováno v:
EBioMedicine, Vol 39, Iss , Pp 83-94 (2019)
Background: Epigenetic histone acetylation is a major event controlling cell functions, such as metabolism, differentiation and repair. Here, we aim to determine whether Valproic acid (VPA), a FDA approved inhibitor of histone deacetylation for bipol
Externí odkaz:
https://doaj.org/article/923afed099b44f48a7ed608827685fb1
Autor:
Michal Halperin-Sternfeld, Gal Netanel Liberman, Raha Kannan, Francesca Netti, Peter X. Ma, Shoshana Malis Arad, Lihi Adler-Abramovich
Publikováno v:
Biomedicines, Vol 10, Iss 6, p 1388 (2022)
Sulfated polysaccharides of red marine microalgae have recently gained much attention for biomedical applications due to their anti-inflammatory and antioxidant properties. However, their low mechanical properties limit their use in tissue engineerin
Externí odkaz:
https://doaj.org/article/da56dd491eab426db94bb2b82a2e7639
Autor:
W. Benton Swanson, Maiko Omi, Seth M. Woodbury, Lindsey M. Douglas, Miranda Eberle, Peter X. Ma, Nan E. Hatch, Yuji Mishina
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 9, p 4499 (2022)
Tissue engineering aims to repair, restore, and/or replace tissues in the human body as an alternative to grafts and prostheses. Biomaterial scaffolds can be utilized to provide a three-dimensional microenvironment to facilitate tissue regeneration.
Externí odkaz:
https://doaj.org/article/a4517768cbc94a979be294a3603e86d0