Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Peter Wieghofer"'
Autor:
Dennis-Dominik Rosmus, Jana Koch, Annika Hausmann, Aude Chiot, Franz Arnhold, Takahiro Masuda, Katrin Kierdorf, Stefanie Marie Hansen, Heidrun Kuhrt, Janine Fröba, Julian Wolf, Stefaniya Boneva, Martin Gericke, Bahareh Ajami, Marco Prinz, Clemens Lange, Peter Wieghofer
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-20 (2024)
Abstract Background The eye is a highly specialized sensory organ which encompasses the retina as a part of the central nervous system, but also non-neural compartments such as the transparent vitreous body ensuring stability of the eye globe and a c
Externí odkaz:
https://doaj.org/article/e84c464330be4cb09d23fcdd4acbbb4d
Autor:
Peipei Zhang, Anja Schlecht, Julian Wolf, Stefaniya Boneva, Yannik Laich, Jana Koch, Franziska Ludwig, Myriam Boeck, Adrian Thien, Carmen Härdtner, Katrin Kierdorf, Hansjürgen Agostini, Günther Schlunck, Marco Prinz, Ingo Hilgendorf, Peter Wieghofer, Clemens Lange
Publikováno v:
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-18 (2021)
Abstract Background Microglia cells represent the resident innate immune cells of the retina and are important for retinal development and tissue homeostasis. However, dysfunctional microglia can have a negative impact on the structural and functiona
Externí odkaz:
https://doaj.org/article/f0b2242fbf2d4c6787d1cd668f61b8e7
Autor:
Andreas Lindhorst, Nora Raulien, Peter Wieghofer, Jens Eilers, Fabio M. V. Rossi, Ingo Bechmann, Martin Gericke
Publikováno v:
Cell Death and Disease, Vol 12, Iss 6, Pp 1-15 (2021)
Abstract A chronic low-grade inflammation within adipose tissue (AT) seems to be the link between obesity and some of its associated diseases. One hallmark of this AT inflammation is the accumulation of AT macrophages (ATMs) around dead or dying adip
Externí odkaz:
https://doaj.org/article/28458dfb9e0141e7b1bfbee40b9a59bc
Autor:
Xinyu Zhuang, Günther Schlunck, Julian Wolf, Dennis-Dominik Rosmus, Tim Bleul, Ren Luo, Daniel Böhringer, Peter Wieghofer, Clemens Lange, Thomas Reinhard, Thabo Lapp
Publikováno v:
Journal of Innate Immunity, Pp 1-14 (2021)
Purpose: The pattern of immune cells infiltrating the corneal stroma has been extensively studied in mice, but data on human tissue have been far less elaborate. To further characterize the number and differentiation state of resident immune cells in
Externí odkaz:
https://doaj.org/article/13af33adc6004a6c9bd500e3244a8b22
Autor:
Dennis-Dominik Rosmus, Peter Wieghofer
Publikováno v:
Neural Regeneration Research, Vol 17, Iss 6, Pp 1275-1277 (2022)
Externí odkaz:
https://doaj.org/article/1fd9722cc8f04a379808650afca6fc5f
Autor:
Julian Wolf, Stefaniya Boneva, Dennis-Dominik Rosmus, Hansjürgen Agostini, Günther Schlunck, Peter Wieghofer, Anja Schlecht, Clemens Lange
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Microglia are the tissue-resident macrophages of the retina and brain, being critically involved in organ development, tissue homeostasis, and response to cellular damage. Until now, little is known about the molecular signature of human retinal micr
Externí odkaz:
https://doaj.org/article/099f2dc871014833af472a271940d16a
Autor:
Anja Schlecht, Peipei Zhang, Julian Wolf, Adrian Thien, Dennis-Dominik Rosmus, Stefaniya Boneva, Günther Schlunck, Clemens Lange, Peter Wieghofer
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2021)
Age-related macular degeneration (AMD) represents the most common cause of blindness in the elderly in the Western world. An impairment of the outer blood-retina barrier and a localized inflammatory microenvironment cause sprouting of choroidal neova
Externí odkaz:
https://doaj.org/article/527e3733b35549a487b86992b2e53fd8
Publikováno v:
Biomedicines, Vol 10, Iss 4, p 840 (2022)
The innate immune landscape of the central nervous system (CNS), including the brain and the retina, consists of different myeloid cell populations with distinct tasks to fulfill. Whereas the CNS borders harbor extraparenchymal CNS-associated macroph
Externí odkaz:
https://doaj.org/article/e7050c0d18a244148b1c37f5092eaa1c
Autor:
Stefaniya Konstantinova Boneva, Julian Wolf, Dennis-Dominik Rosmus, Anja Schlecht, Gabriele Prinz, Yannik Laich, Myriam Boeck, Peipei Zhang, Ingo Hilgendorf, Andreas Stahl, Thomas Reinhard, James Bainbridge, Günther Schlunck, Hansjürgen Agostini, Peter Wieghofer, Clemens A. K. Lange
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
PurposeTo decipher the transcriptional signature of macrophages of the human vitreous, also known as hyalocytes, and compare it to the profiles of other myeloid cell populations including human blood-derived monocytes, macrophages, and brain microgli
Externí odkaz:
https://doaj.org/article/96c1a1414452466caff6b871446a2640
Autor:
Simone Brioschi, Paolo d’Errico, Lukas S. Amann, Hana Janova, Sonja M. Wojcik, Melanie Meyer-Luehmann, Lawrence Rajendran, Peter Wieghofer, Rosa C. Paolicelli, Knut Biber
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 13 (2020)
A growing body of evidence indicates that microglia actively remove synapses in vivo, thereby playing a key role in synaptic refinement and modulation of brain connectivity. This phenomenon was mainly investigated in immunofluorescence staining and c
Externí odkaz:
https://doaj.org/article/4212dc9e7c4743df81cd46c466e44482