Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Peter Walentek"'
Autor:
Takayuki Yasunaga, Johannes Wiegel, Max D. Bergen, Martin Helmstädter, Daniel Epting, Andrea Paolini, Özgün Çiçek, Gerald Radziwill, Christina Engel, Thomas Brox, Olaf Ronneberger, Peter Walentek, Maximilian H. Ulbrich, Gerd Walz
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/00aeda8f768e412b8ffc6a7ae58d1c7b
Autor:
Alexandra A. Vetrova, Daria M. Kupaeva, Alena Kizenko, Tatiana S. Lebedeva, Peter Walentek, Nikoloz Tsikolia, Stanislav V. Kremnyov
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract Brachyury, a member of T-box gene family, is widely known for its major role in mesoderm specification in bilaterians. It is also present in non-bilaterian metazoans, such as cnidarians, where it acts as a component of an axial patterning sy
Externí odkaz:
https://doaj.org/article/3c607c6cf0244aa0b126bfad992b89ed
Autor:
Takayuki Yasunaga, Johannes Wiegel, Max D. Bergen, Martin Helmstädter, Daniel Epting, Andrea Paolini, Özgün Çiçek, Gerald Radziwill, Christina Engel, Thomas Brox, Olaf Ronneberger, Peter Walentek, Maximilian H. Ulbrich, Gerd Walz
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Abstract Several tissues contain cells with multiple motile cilia that generate a fluid or particle flow to support development and organ functions; defective motility causes human disease. Developmental cues orient motile cilia, but how cilia are lo
Externí odkaz:
https://doaj.org/article/323e8d3a72bc4cfb83661eb8fc68dd19
Autor:
Anja Beckers, Franziska Fuhl, Tim Ott, Karsten Boldt, Magdalena Maria Brislinger, Peter Walentek, Karin Schuster-Gossler, Jan Hegermann, Leonie Alten, Elisabeth Kremmer, Adina Przykopanski, Katrin Serth, Marius Ueffing, Martin Blum, Achim Gossler
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Cilia are protrusions of the cell surface and composed of hundreds of proteins many of which are evolutionary and functionally well conserved. In cells assembling motile cilia the expression of numerous ciliary components is under the contro
Externí odkaz:
https://doaj.org/article/4e99c332b9ed4435a10fd923ac28beb1
Autor:
Dinu Antony, Elif Gulec Yilmaz, Alper Gezdirici, Lennart Slagter, Zeineb Bakey, Helen Bornaun, Ibrahim Cansaran Tanidir, Tran Van Dinh, Han G. Brunner, Peter Walentek, Sebastian J. Arnold, Rolf Backofen, Miriam Schmidts
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Laterality defects are defined by the perturbed left–right arrangement of organs in the body, occurring in a syndromal or isolated fashion. In humans, primary ciliary dyskinesia (PCD) is a frequent underlying condition of defective left–right pat
Externí odkaz:
https://doaj.org/article/4e48fa0a6a1249bf9f4769be2632b89b
Autor:
Maximilian Haas, José Luis Gómez Vázquez, Dingyuan Iris Sun, Hong Thi Tran, Magdalena Brislinger, Alexia Tasca, Orr Shomroni, Kris Vleminckx, Peter Walentek
Publikováno v:
Cell Reports, Vol 28, Iss 13, Pp 3338-3352.e6 (2019)
Summary: Mucociliary epithelia provide a first line of defense against pathogens. Impaired regeneration and remodeling of mucociliary epithelia are associated with dysregulated Wnt/β-catenin signaling in chronic airway diseases, but underlying mecha
Externí odkaz:
https://doaj.org/article/626f48ba906f45f1af09aaa0f6d117fc
Autor:
Peter Walentek, Cathrin Hagenlocher, Tina Beyer, Christina Müller, Kerstin Feistel, Axel Schweickert, Richard M. Harland, Martin Blum
Publikováno v:
Data in Brief, Vol 4, Iss C, Pp 22-31 (2015)
During gastrulation and neurulation, foxj1 expression requires ATP4a-dependent Wnt/β-catenin signaling for ciliation of the gastrocoel roof plate (Walentek et al. Cell Rep. 1 (2012) 516–527.) and the mucociliary epidermis (Walentek et al. Dev. Bio
Externí odkaz:
https://doaj.org/article/2c17ae11990049f7b86b9f6954a28bc6
Publikováno v:
Cell Reports, Vol 10, Iss 4, Pp 527-536 (2015)
Alternative splicing is pervasive in vertebrates, yet little is known about most isoforms or their regulation. transformer-2b (tra2b) encodes a splicing regulator whose endogenous function is poorly understood. Tra2b knockdown in Xenopus results in e
Externí odkaz:
https://doaj.org/article/4e917aed01e146c7bb3430b8cc021523
Autor:
Peter Walentek, Ian K Quigley, Dingyuan I Sun, Umeet K Sajjan, Christopher Kintner, Richard M Harland
Publikováno v:
eLife, Vol 5 (2016)
Upon cell cycle exit, centriole-to-basal body transition facilitates cilia formation. The centriolar protein Cp110 is a regulator of this process and cilia inhibitor, but its positive roles in ciliogenesis remain poorly understood. Using Xenopus we s
Externí odkaz:
https://doaj.org/article/4e27a14dced0441298cbcaeed6db559d
Publikováno v:
Cell Reports, Vol 1, Iss 5, Pp 516-527 (2012)
Most vertebrate embryos break symmetry by a cilia-driven leftward flow during neurulation. In the frog Xenopus asymmetric expression of the ion pump ATP4a was reported at the 4-cell stage. The “ion-flux” model postulates that symmetry is broken f
Externí odkaz:
https://doaj.org/article/ba8f65962ebf4e7293caa6b8034fb233