Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Peter W. J. Morrison"'
Publikováno v:
Pharmaceutics, Vol 11, Iss 7, p 321 (2019)
There are more than 100 recognized disorders of the eye. This makes the development of advanced ocular formulations an important topic in pharmaceutical science. One of the ways to improve drug delivery to the eye is the use of penetration enhancers.
Externí odkaz:
https://doaj.org/article/1f42cd4f4f524633bf4f8480d46c9aec
Autor:
Andrea Brancale, Charles Martin Heard, David Whitaker, Melissa Fallon, Matthew J. Burton, Carmine Varricchio, Hannah M. Boostrom, Philip N. Lewis, Siân R. Morgan, Peter W. J. Morrison, Andrew J. Quantock, Melissa G. Hewitt
Publikováno v:
Molecular Pharmaceutics. 17:1428-1441
Microbial keratitis is a severe, sight-threatening condition caused by various pathogens. Eyedrops are the standard delivery modality for treating these disorders; however, blinking reflex, elevated tear production, and nasolacrimal drainage eliminat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c88f4649d4f3f59d0c57e6b00e02a240
https://doi.org/10.1021/acs.molpharmaceut.0c00140
https://doi.org/10.1021/acs.molpharmaceut.0c00140
Autor:
David Whitaker, Andrew J. Quantock, Nicole Pilia, Peter W. J. Morrison, Siân R. Morgan, Philip N. Lewis, Charles Martin Heard, Melissa G. Hewitt, Steven L. Kelly, Ryan Moseley, Rachael L. Moses, Josie E. Parker
Acanthamoeba keratitis is caused by a protozoal infection of the cornea, with 80% of cases involving the improper use of contact lenses. The infection causes intense pain and is potentially blinding. However, early diagnosis improves treatment effica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04c3dc3ed397f48da2870ca10f25c660
https://cronfa.swan.ac.uk/Record/cronfa53795
https://cronfa.swan.ac.uk/Record/cronfa53795
Publikováno v:
Pharmaceutics
Pharmaceutics, Vol 11, Iss 7, p 321 (2019)
Pharmaceutics, Vol 11, Iss 7, p 321 (2019)
There are more than 100 recognized disorders of the eye. This makes the development of advanced ocular formulations an important topic in pharmaceutical science. One of the ways to improve drug delivery to the eye is the use of penetration enhancers.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e258f5e4eb93400376c76f84cb15bf92
https://centaur.reading.ac.uk/84879/3/pharmaceutics-11-00321-v2.pdf
https://centaur.reading.ac.uk/84879/3/pharmaceutics-11-00321-v2.pdf
Autor:
Peter W J, Morrison, Natalia N, Porfiryeva, Sukhmanpreet, Chahal, Ilgiz A, Salakhov, Charlène, Lacourt, Irina I, Semina, Rouslan I, Moustafine, Vitaliy V, Khutoryanskiy
Publikováno v:
Molecular pharmaceutics. 14(10)
Crown ethers are cyclic molecules consisting of a ring containing several ether groups. The most common and important members of this series are 12-crown-4 (12C4), 15-crown-5 (15C5), and 18-crown-6 (18C6). These container molecules have the ability t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e8fffe4c06c380296cbfe1b27b23e85e
https://pubmed.ncbi.nlm.nih.gov/28825493
https://pubmed.ncbi.nlm.nih.gov/28825493
Publikováno v:
Therapeutic delivery. 5(12)
Various strategies for ocular drug delivery are considered; from basic formulation techniques for improving availability of drugs; viscosity enhancers and mucoadhesives aid drug retention and penetration enhancers promote drug transport into the eye.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1e70ba06e5c5a117cc904ef11339c1fe
https://pubmed.ncbi.nlm.nih.gov/25531930
https://pubmed.ncbi.nlm.nih.gov/25531930
Publikováno v:
Molecular pharmaceutics. 11(10)
Overcoming the natural defensive barrier functions of the eye remains one of the greatest challenges of ocular drug delivery. Cornea is a chemical and mechanical barrier preventing the passage of any foreign bodies including drugs into the eye, but t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::559c4064cabf6e044b082cf3887b45ed
https://pubmed.ncbi.nlm.nih.gov/25165886
https://pubmed.ncbi.nlm.nih.gov/25165886
Publikováno v:
Mucoadhesive Materials and Drug Delivery Systems
Treating ocular disorders presents many problems for drug delivery. The preferred means for ocular drug delivery is via the topical route, due to ease of access and patient compliance. Ocular mucosa plays an important role in drug delivery and is the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::adfa7ee46b22a286723624cc79b875df
https://doi.org/10.1002/9781118794203.ch02
https://doi.org/10.1002/9781118794203.ch02
Autor:
Olga V, Khutoryanskaya, Peter W J, Morrison, Serzhan K, Seilkhanov, Marat N, Mussin, Elvira K, Ozhmukhametova, Tolebai K, Rakhypbekov, Vitaliy V, Khutoryanskiy
Publikováno v:
Macromolecular bioscience. 14(2)
Poly(acrylic acid) (PAA) and methylcellulose (MC) are able to form hydrogen-bonded interpolymer complexes (IPCs) in aqueous solutions. In this study, the complexation between PAA and MC is explored in dilute aqueous solutions under acidic conditions.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::90fc71e5791e3a2bd622a56a28d4257f
https://pubmed.ncbi.nlm.nih.gov/24106128
https://pubmed.ncbi.nlm.nih.gov/24106128
Publikováno v:
Journal of Biological Chemistry. 271:12891-12896
The epidermal growth factor receptor (EGFR) is regulated by at least two mechanisms involving protein kinase C (PKC), inhibition of EGF binding and inhibition of EGF-stimulated tyrosine kinase activity. In this study we investigated whether mitogen-a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5dfab96709875f24b0491e284d50e68
https://doi.org/10.1074/jbc.271.22.12891
https://doi.org/10.1074/jbc.271.22.12891