Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Peter W. H. Wan"'
Publikováno v:
Biotechnology Set. :536-587
Autor:
Stanley M. Roberts, Peter W. H. Wan
Publikováno v:
Journal of Molecular Catalysis B: Enzymatic. 4:111-136
Preparative-scale biotransformations of cyclic and bicyclic ketones yielding optically active lactones are illustrated. The use of whole cell systems such as Acinetobacter calcoaceticus to stereoselectively oxidize bicycle[3.2.0]heptanones and bicycl
Autor:
M. Teresa Bes, Raymond Mccague, Stanley M. Roberts, Brian Adger, Sandrine Pedragosa-Moreau, Gideon Grogan, Andrew J. Willets, Peter W. H. Wan, Raffaella Villa
Publikováno v:
Bioorganic & Medicinal Chemistry. 5:253-261
2-(2-Acetoxyethyl)cyclohexanone ( 4 ) was converted into the lactone (−)-( 5 ) regio- and enantioselectively using 2-oxo-Δ 3 -4,5,5-trimethylcyclopentenyl acetyl-CoA monooxygenase, an NADPH-dependent Baeyer-Villiger monooxygenase from camphor grow
Autor:
Peter W. H. Wan, Anthony G. M. Barrett
Publikováno v:
The Journal of Organic Chemistry. 61:8667-8670
Autor:
Andrew Willetts, Peter W. H. Wan, Christopher J. Knowles, David E. Hibbs, Adel K. Mish'al, Stanley M. Roberts, Gideon Grogan, Michael B. Hursthouse, Jassem G. Mahdi, Michael Wright, David R. Kelly, Ian N. Taylor
Publikováno v:
J. Chem. Soc., Perkin Trans. 1. :2057-2066
An active-site model for enzyme-catalysed Baeyer–Villiger reactions is proposed and tested by transformation of the tricyclic ketone 6 to the lactone 7( > 98% ee) using purified enzymes from Acinetobacter sp. NCIMB 9871 and Pseudomonas putida NCIMB
Publikováno v:
Biotechnology Letters. 16:1173-1178
Conditions have been devised to enable partially purified enzyme preparations from camphor-grownPseudomonas putida NCIMB 10007 to undertake oxidative and reductive biotransformations of 5-hexylcyclopent-2-enone.
Autor:
Gideon Grogan, Stanley M. Roberts, Andrew Willetts, Melissa S. Levitt, René Gagnon, Peter W. H. Wan
Publikováno v:
J. Chem. Soc., Perkin Trans. 1. :2537-2543
A. calcoaceticus NCIMB 9871 and Ps. putida NCIMB 10007 [grown on (+)-camphor] have been utilized as biocatalysts in Baeyer–Villiger oxidations. The former microorganism oxidized the racemic ketone 6 non-selectively but transformed the dihalogeno ke
Publikováno v:
Biotechnology Letters. 15:913-918
Both NADH- and NADPH-dependent Baeyer-Villiger monooxygenase activities with potential uses as biocatalysts for biotransformations are present to different extents throughout the growth of Pseudomonas putida NCIMB 10007 on (+)-camphor. The two activi
Autor:
Gideon Grogan, Ray McCague, Brian M. Adger, M. T. Bes, Sandrine Pedragosa-Moreau, Stanley M. Roberts, Peter W. H. Wan, Andrew Willetts, Raffaella Villa
Publikováno v:
ChemInform. 26
Autor:
Anthony G. M. Barrett, Peter W. H. Wan
Publikováno v:
ChemInform. 28