Zobrazeno 1 - 10
of 187
pro vyhledávání: '"Peter W. Gage"'
Autor:
Brett A. Lidbury, Gerald M. McInerney, Andres Merits, Suresh Mahalingam, Liis Karo-Astover, Kuo-Ching Sheng, Julian V. Melton, Bastian Thaa, Michelle Nelson, Lara J. Herrero, Peter W. Gage, Adam Taylor, Gary Ewart
Publikováno v:
Journal of Virology. 90:4150-4159
The alphaviral 6k gene region encodes the two structural proteins 6K protein and, due to a ribosomal frameshift event, the transframe protein (TF). Here, we characterized the role of the 6k proteins in the arthritogenic alphavirus Ross River virus (R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::465b1e3368a2f40502855d8d0b9818b7
https://doi.org/10.1128/jvi.03192-15
https://doi.org/10.1128/jvi.03192-15
Autor:
Esther M. Gallant, Yasser A. Abdellatif, Philip G. Board, Peter W. Gage, Angela F. Dulhunty, Dan Liu
Publikováno v:
Cell Calcium. 41:429-440
Members of the glutathione transferase (GST) structural family are novel regulators of cardiac ryanodine receptor (RyR) calcium channels. We present the first detailed report of the effect of endogenous muscle GST on skeletal and cardiac RyRs. An Mu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f2f484a74d99c151adfcd890cc407ad
https://doi.org/10.1016/j.ceca.2006.08.004
https://doi.org/10.1016/j.ceca.2006.08.004
Publikováno v:
Virology
All coronaviruses encode a small hydrophobic envelope (E) protein, which mediates viral assembly and morphogenesis by an unknown mechanism. We have previously shown that the E protein from Severe Acute Respiratory Syndrome coronavirus (SARS-CoV) form
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a2ffc7f39cd0c7364e8ac0127c0435e
https://doi.org/10.1016/j.virol.2006.05.028
https://doi.org/10.1016/j.virol.2006.05.028
Publikováno v:
Biochemical Journal. 390:333-343
The recently discovered CLIC-2 protein (where CLIC stands for chloride intracellular channel), which belongs to the ubiquitous glutathione transferase structural family and is expressed in the myocardium, is a regulator of native cardiac RyR2 (ryanod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a4569c969e45b962e2e4b6d2978d168
https://doi.org/10.1042/bj20042113
https://doi.org/10.1042/bj20042113
Publikováno v:
Journal of Membrane Biology. 205:17-28
GABA(A) receptors composed of alpha, beta and gamma subunits display a significantly higher single-channel conductance than receptors comprised of only alpha and beta subunits. The pore of GABA(A) receptors is lined by the second transmembrane region
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b84871ae9926b8717dddc4c3e109dad
https://doi.org/10.1007/s00232-005-0759-2
https://doi.org/10.1007/s00232-005-0759-2
Publikováno v:
Antiviral Therapy. 11:289-295
A chemically synthesized peptide representing the C-terminal subunit (p13-C) of the p13 protein of GB virus B (GBV-B), the most closely related virus to hepatitis C virus (HCV) showed ion channel activity in artificial lipid bilayers. The channels ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c1bbc1ea78c9fd19bf30f46ac69386f
https://doi.org/10.1177/135965350601100311
https://doi.org/10.1177/135965350601100311
Publikováno v:
Virology
Severe Acute Respiratory Syndrome (SARS) is caused by a novel coronavirus (SARS-CoV). Coronaviruses including SARS-CoV encode an envelope (E) protein, a small, hydrophobic membrane protein. We report that, in planar lipid bilayers, synthetic peptides
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ffe1e8b6d39c8d7950748ae496f63a2
Publikováno v:
Antimicrobial Agents and Chemotherapy. 48:2325-2330
We report that the amiloride analogues 5-( N , N -hexamethylene)amiloride and 5-( N , N -dimethyl)amiloride inhibit, at micromolar concentrations, the replication of human immunodeficiency virus type 1 (HIV-1) in cultured human blood monocyte-derived
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7229c2f21e0eaa4952f9bc16a5f0558
https://doi.org/10.1128/aac.48.6.2325-2330.2004
https://doi.org/10.1128/aac.48.6.2325-2330.2004
Autor:
Tien Luu, Richard W. Olsen, Andrea B. Everitt, M. Louise Tierney, Bryndis Birnir, Peter W. Gage, Brett A. Cromer
Publikováno v:
Journal of Biological Chemistry. 279:21701-21706
High conductance gamma-aminobutyric acid type A (GABA(A)) channels (>40 picosiemens (pS)) have been reported in some studies on GABA(A) channels in situ but not in others, whereas recombinant GABA(A) channels do not appear to display conductances abo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a09a8831e8886df8fd35041a30db4090
https://doi.org/10.1074/jbc.m312806200
https://doi.org/10.1074/jbc.m312806200
Publikováno v:
The Journal of Physiology. 552:13-22
Neurons were obtained from the CA1 region of the hippocampus of newborn rats and maintained in culture. Channels were activated by pentobarbitone in cell-attached, inside-out or outside-out patches, normally by applying pentobarbitone in flowing bath
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::975e4830853415622387954a35b296ec
https://doi.org/10.1113/jphysiol.2003.047415
https://doi.org/10.1113/jphysiol.2003.047415