Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Peter W., Tsao"'
Autor:
Moorthy S. S. Palanki, Lynn J. Ransone, Minghuan Ren, Ryuichi Totsuka, Sonal Desai, Arnie Ow, Paul Erdman, Peter W. Tsao, Cheryl Spooner, Brydon L. Bennett, Mark J. Suto, Wataru Toriumi, Anthony M. Manning
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 13:4077-4080
We have developed novel orally active quinazoline analogues as inhibitors of AP-1 and NF-κB mediated transcriptional activation. Among the derivatives prepared, 1-[2-(2-thienyl)quinazolin-4-ylamino]-3-methyl-3-pyrroline-2,5-dione ( 10 ) showed signi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53dea96edefc7cf5e62bc9d946524597
https://doi.org/10.1016/j.bmcl.2003.08.047
https://doi.org/10.1016/j.bmcl.2003.08.047
Publikováno v:
Japanese Journal of Pharmacology. 78:225-228
This study demonstrated the decrease of bone mineral density (BMD) in the type II collagen (CII)-induced arthritis (CIA) model in rats and the relationship between BMD and paw edema and the effect of dexamethasone-21-phosphate (DEX). The paw swelling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::169878ed40b6c13d23a8b2b474810334
https://doi.org/10.1254/jjp.78.225
https://doi.org/10.1254/jjp.78.225
Autor:
Robert S. Schwartz, Thomas M. Reilly, Sanjay S. Srivatsa, Lorraine A. Fitzpatrick, Shaker A. Mousa, Peter W. Tsao, David R. Holmes
Publikováno v:
Cardiovascular Research. 36:408-428
Lumen loss from vascular restenosis remains a leading cause of chronic revascularization failure. Objective : We hypothesized that cell-matrix adhesion, migration, and differentiation events that underlie restenosis are mediated by αvβ3 integrin-li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17bb9df400a666b00bf20310b871b1d8
https://doi.org/10.1016/s0008-6363(97)00184-3
https://doi.org/10.1016/s0008-6363(97)00184-3
Publikováno v:
Clinical Immunology and Immunopathology. 84:166-170
This study demonstrates that systemic and local decreases in bone mineral density (BMD) occurred with Freund's complete adjuvant injection in the rat right footpad using dual energy X-ray absorptiometry. The rats were assigned to either adjuvant-trea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1c7c57a78c4c9913748b7768623ff28
https://doi.org/10.1006/clin.1997.4373
https://doi.org/10.1006/clin.1997.4373
Autor:
Sandra K. Flint, Mark S. Forsythe, Shaker A. Mousa, Sharon A. Jackson, Peter W. Tsao, Jeffrey M. Bozarth
Publikováno v:
Thrombosis Research. 77:543-556
DMP 728 is a potent and specific platelet GPIIb/IIIa antagonist. Like all GPIIb/IIIa antagonists, DMP 728 has a steep dose-response relationship in inhibiting platelet aggregation. In this study the relationships between receptor occupancy, platelet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e71a6ed734c1f4cc56e8a77f7a9271f5
https://doi.org/10.1016/0049-3848(95)00029-1
https://doi.org/10.1016/0049-3848(95)00029-1
Autor:
Jill Waddell, Peter W. Tsao, Diane Parkinson, John G. Coles, Ingeborg C. Radde, Roberto J. Diaz, Greg J. Wilson, Gordon B. Mills
Publikováno v:
Transplantation. 58:451-457
Tyrosine phosphorylation is an early, critical event in lymphocyte signal transduction. We measured tyrosine phosphorylation in a porcine experimental transplant model to evaluate its utility in monitoring the allograft immune response. Using flow cy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3617f4dd88e59b4251e851c1eb09350f
https://doi.org/10.1097/00007890-199408270-00011
https://doi.org/10.1097/00007890-199408270-00011
Autor:
Jannet Augustine, Anna Brezina, Lee N. Benson, Gregory J. Wilson, Peter W. Tsao, Joseph Caspi, Stanley L Herman, John G. Coles, Arnost Kolin
Publikováno v:
The Journal of Thoracic and Cardiovascular Surgery. 105:59-67
Administration of catecholamines to newborn infants may potentiate reperfusion injury because of increased transsarcolemmal Ca2+ influx and the presence of less developed sarcoplasmic reticulum in the immature hearts. We investigated the effect of ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a74c72d4272d339f19ffa920ffcc14a4
https://doi.org/10.1016/s0022-5223(19)33848-6
https://doi.org/10.1016/s0022-5223(19)33848-6
Autor:
Peter W. Tsao, Shinya Ito, Pui Y. Wong, Ingeborg C. Radde, Scott Bryson, David S. Young, Joseph Caspi, Roberto J. Diaz, Maureen F. Martell, Janet M. Augustine, Greg J. Wilson, John G. Coles
Publikováno v:
Developmental Pharmacology and Therapeutics. 18:20-25
The disposition kinetics of cyclosporin A in the neonates as well as age-related differences in lymphocyte responses to cyclosporin A are unknown. A single intravenous infusion of cyclosporin A was given to neonatal (2.5 or 5 mg/kg) and mature pigs (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d437833395df7ea03d17895188ff71fd
https://doi.org/10.1159/000480594
https://doi.org/10.1159/000480594
Autor:
Janet M. Augustine, Maureen F. Martell, Roberto J. Diaz, Peter W. Tsao, John G. Coles, Ingeborg C. Radde, Greg J. Wilson, Pui Y. Wong
Publikováno v:
Transplantation. 52:345-348
The effect of cyclosporine on lymphocyte intracellular free calcium [( Ca2+]i) is controversial, and potential age-related differences in lymphocyte CsA sensitivity have not been studied. We measured the mitogen-induced change in [Ca2+]i in periphera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8d16cef325f1451cd437be9a27c5fee
https://doi.org/10.1097/00007890-199108000-00031
https://doi.org/10.1097/00007890-199108000-00031
Publikováno v:
Neonatology. 57:250-256
Nephrocalcinosis has been observed in premature infants treated with furosemide. To see whether furosemide-induced renal calcium accumulation is reflected in easily accessible extrarenal cells, we measured cytosolic free calcium ([Ca2+]i) in blood mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81e0889ee6462f56d96b161faae5330e
https://doi.org/10.1159/000243199
https://doi.org/10.1159/000243199