Zobrazeno 1 - 10
of 255
pro vyhledávání: '"Peter W Andrew"'
Autor:
Joseph J Wanford, PhD, Ryan G Hames, BSc, David Carreno, PhD, Zydrune Jasiunaite, BSc, Wen Y Chung, PhD, Fabio Arena, MD, Vincenzo Di Pilato, PhD, Kornelis Straatman, PhD, Kevin West, ProfPhD, Robeena Farzand, PhD, Mariagrazia Pizza, MA, Luisa Martinez-Pomares, PhD, Peter W Andrew, ProfPhD, E Richard Moxon, ProfFRS, Ashley R Dennison, ProfMD, Gian Maria Rossolini, ProfMD, Marco R Oggioni, ProfMD
Publikováno v:
The Lancet Microbe, Vol 2, Iss 12, Pp e695-e703 (2021)
Summary: Background: Hypervirulent Klebsiella pneumoniae (hvKp) strains of capsule type K1 and K2 cause invasive infections associated with hepatic abscesses, which can be difficult to treat and are frequently associated with relapsing infections. Ot
Externí odkaz:
https://doaj.org/article/98b688093a574746b4bdada9d71052cd
Autor:
Vitor E Fernandes, Giuseppe Ercoli, Alan Bénard, Carolin Brandl, Hannah Fahnenstiel, Jennifer Müller-Winkler, Georg F Weber, Paul Denny, Lars Nitschke, Peter W Andrew
Publikováno v:
PLoS Pathogens, Vol 16, Iss 4, p e1008464 (2020)
Streptococcus pneumoniae is a major human pathogen, causing pneumonia and sepsis. Genetic components strongly influence host responses to pneumococcal infections, but the responsible loci are unknown. We have previously identified a locus on mouse ch
Externí odkaz:
https://doaj.org/article/07bcfc37f2ab46e9a4c9cab408037570
Publikováno v:
PLoS Pathogens, Vol 13, Iss 3, p e1006263 (2017)
Pneumococcal neuraminidase is a key enzyme for sequential deglycosylation of host glycans, and plays an important role in host survival, colonization, and pathogenesis of infections caused by Streptococcus pneumoniae. One of the factors that can affe
Externí odkaz:
https://doaj.org/article/53344bb2de584a8e89a2950755a25310
Autor:
Banaz O. Kareem, Ozcan Gazioglu, Karina Mueller Brown, Medhanie Habtom, David G. Glanville, Marco R. Oggioni, Peter W. Andrew, Andrew T. Ulijasz, N. Luisa Hiller, Hasan Yesilkaya
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract Efficient utilization of nutrients is crucial for microbial survival and virulence. The same nutrient may be utilized by multiple catabolic pathways, indicating that the physical and chemical environments for induction as well as their funct
Externí odkaz:
https://doaj.org/article/840da3ea4d0c46ed888ca161c68c4584
Autor:
Carl Leung, Natalya V Dudkina, Natalya Lukoyanova, Adrian W Hodel, Irene Farabella, Arun P Pandurangan, Nasrin Jahan, Mafalda Pires Damaso, Dino Osmanović, Cyril F Reboul, Michelle A Dunstone, Peter W Andrew, Rana Lonnen, Maya Topf, Helen R Saibil, Bart W Hoogenboom
Publikováno v:
eLife, Vol 4 (2015)
Externí odkaz:
https://doaj.org/article/3ccb4083d8e948e290b3b3a5965a0e9c
Autor:
Laura Paixão, Joana Oliveira, André Veríssimo, Susana Vinga, Eva C Lourenço, M Rita Ventura, Morten Kjos, Jan-Willem Veening, Vitor E Fernandes, Peter W Andrew, Hasan Yesilkaya, Ana Rute Neves
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0121042 (2015)
The human pathogen Streptococcus pneumoniae is a strictly fermentative organism that relies on glycolytic metabolism to obtain energy. In the human nasopharynx S. pneumoniae encounters glycoconjugates composed of a variety of monosaccharides, which c
Externí odkaz:
https://doaj.org/article/b7ebd0e9277948dabb5ee5e0c3fb79ab
Autor:
Carl Leung, Natalya V Dudkina, Natalya Lukoyanova, Adrian W Hodel, Irene Farabella, Arun P Pandurangan, Nasrin Jahan, Mafalda Pires Damaso, Dino Osmanović, Cyril F Reboul, Michelle A Dunstone, Peter W Andrew, Rana Lonnen, Maya Topf, Helen R Saibil, Bart W Hoogenboom
Publikováno v:
eLife, Vol 3 (2014)
Membrane attack complex/perforin/cholesterol-dependent cytolysin (MACPF/CDC) proteins constitute a major superfamily of pore-forming proteins that act as bacterial virulence factors and effectors in immune defence. Upon binding to the membrane, they
Externí odkaz:
https://doaj.org/article/95f4b1baef534ae3afce743c4f6eaf48
Autor:
Alice Gerlini, Leonarda Colomba, Leonardo Furi, Tiziana Braccini, Ana Sousa Manso, Andrea Pammolli, Bo Wang, Antonio Vivi, Maria Tassini, Nico van Rooijen, Gianni Pozzi, Susanna Ricci, Peter W Andrew, Uwe Koedel, E Richard Moxon, Marco R Oggioni
Publikováno v:
PLoS Pathogens, Vol 10, Iss 3, p e1004026 (2014)
The pathogenesis of bacteraemia after challenge with one million pneumococci of three isogenic variants was investigated. Sequential analyses of blood samples indicated that most episodes of bacteraemia were monoclonal events providing compelling evi
Externí odkaz:
https://doaj.org/article/21e737eb66174879853e696cc2071d0a
Autor:
Claire M Smith, Stephen C Fry, Kevin C Gough, Alexandra J F Patel, Sarah Glenn, Marie Goldrick, Ian S Roberts, Garry C Whitelam, Peter W Andrew
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e88144 (2014)
Bacterial polysaccharides have numerous clinical or industrial uses. Recombinant plants could offer the possibility of producing bacterial polysaccharides on a large scale and free of contaminating bacterial toxins and antigens. We investigated the f
Externí odkaz:
https://doaj.org/article/8fae85e12181461ab653e26848d74f08
Autor:
Magda S Jonczyk, Michelle Simon, Saumya Kumar, Vitor E Fernandes, Nicolas Sylvius, Ann-Marie Mallon, Paul Denny, Peter W Andrew
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e89831 (2014)
Streptococcus pneumoniae is an important human pathogen responsible for high mortality and morbidity worldwide. The susceptibility to pneumococcal infections is controlled by as yet unknown genetic factors. To elucidate these factors could help to de
Externí odkaz:
https://doaj.org/article/751b2a3e9fa44b40aa05bdb2caa6588f