Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Peter W, Hoffman"'
Publikováno v:
Journal of Biological Chemistry. 279:17449-17458
The NR1 gene undergoes induction in neurogenesis mainly via promoter de-repression, and up-regulation during neuronal differentiation by undefined mechanism(s). Here, we show that in the distal region the NR1 promoter has an active NF-kappaB site sha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea46b4d9618d2afa624f64663aaf2f48
https://doi.org/10.1074/jbc.m311267200
https://doi.org/10.1074/jbc.m311267200
Publikováno v:
Journal of Neurochemistry. 86:992-1005
To understand the genetic mechanism controlling the expression of the NMDA subtype of glutamate receptors during neuronal differentiation, we studied activation of the N-methyl-D-aspartate receptor subunit 1 (NR1) gene and the role of the repressor e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cde6506420de043e8693e3c3509fe881
https://doi.org/10.1046/j.1471-4159.2003.01922.x
https://doi.org/10.1046/j.1471-4159.2003.01922.x
Publikováno v:
Journal of Biological Chemistry. 278:26423-26434
N-Methyl-d-aspartate (NMDA) receptor subunit 2A (NR2A) is an important modulatory component of the NMDA subtype of glutamate receptors. To investigate the transcription mechanism of the NR2A gene, we cloned the 5′-flanking sequence from a rat genom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c17403a823726c205b5d682dd538686
https://doi.org/10.1074/jbc.m211165200
https://doi.org/10.1074/jbc.m211165200
Autor:
Peter W. Hoffman, Jeffrey M. Chernak
Publikováno v:
Nucleic Acids Research. 23:2229-2235
Two DNA elements which we have termed SAA and GAG have been shown to control expression of the rat amyloid precursor protein (APP) gene, and the region containing the SAA element has been shown to interact with nuclear proteins [Hoffman and Chernak (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6326007d7d87680523b92e6b9b2d843
https://doi.org/10.1093/nar/23.12.2229
https://doi.org/10.1093/nar/23.12.2229
Publikováno v:
Journal of neurochemistry. 86(4)
To understand the genetic mechanism controlling the expression of the NMDA subtype of glutamate receptors during neuronal differentiation, we studied activation of the N-methyl-D-aspartate receptor subunit 1 (NR1) gene and the role of the repressor e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f39d4a976b781ce3edece85e948b3f19
https://pubmed.ncbi.nlm.nih.gov/12887696
https://pubmed.ncbi.nlm.nih.gov/12887696
Publikováno v:
The Journal of biological chemistry. 278(29)
N-Methyl-d-aspartate (NMDA) receptor subunit 2A (NR2A) is an important modulatory component of the NMDA subtype of glutamate receptors. To investigate the transcription mechanism of the NR2A gene, we cloned the 5'-flanking sequence from a rat genomic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::56a16793386ae15d9e6065b1bf295ff5
https://pubmed.ncbi.nlm.nih.gov/12746457
https://pubmed.ncbi.nlm.nih.gov/12746457
Publikováno v:
Brain research. Molecular brain research. 44(1)
Alterations in the number or functional state of D2 dopamine receptors have been implicated in the decreased motor abilities associated with normal aging, Parkinson's disease and other neurodegenerative diseases. Previous work has demonstrated a subs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e99e8b1da92d5128a373c4dc3f59026b
https://pubmed.ncbi.nlm.nih.gov/9030705
https://pubmed.ncbi.nlm.nih.gov/9030705
Autor:
Peter W. Hoffman, John P. Merlie, Zhican Qu, Elizabeth D. Apel, Richard L. Huganir, Carol A. Doherty
Publikováno v:
Molecular and cellular neurosciences. 8(2-3)
Protein tyrosine phosphorylation has been suggested to play an important role in the clustering of the nicotinic acetylcholine receptor (AChR) at the developing neuromuscular junction. Recent studies have shown that the 43-kDa synapse-associated prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3672c3500ee03f40e2a5a8a060cce5f
https://pubmed.ncbi.nlm.nih.gov/8918833
https://pubmed.ncbi.nlm.nih.gov/8918833
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 14(7)
The nicotinic acetylcholine receptor (AChR) is a pentameric complex made up of four types of subunits in the stoichiometry alpha 2 beta gamma delta. These subunits have been shown to be differentially phosphorylated by cAMP-dependent protein kinase (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15cb452b2135e2e39efe64991a72aeb8
https://pubmed.ncbi.nlm.nih.gov/8027770
https://pubmed.ncbi.nlm.nih.gov/8027770