Zobrazeno 1 - 10 of 27 pro vyhledávání: '"Peter Volkers"'
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Structure functional insights into calcium binding during the activation of coagulation factor XIII A
Autor: Johannes Dodt, Arijit Biswas, Diana Imhof, Emma Hethershaw, Peter Volkers, S. Singh, Vytautus Ivaskevicius, Johannes Oldenburg, Helen Philippou
Publikováno v: Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-18 (2019)
The dimeric FXIII-A2, a pro-transglutaminase is the catalytic part of the heterotetrameric coagulation FXIII-A2B2 complex that upon activation by calcium binding/thrombin cleavage covalently cross-links preformed fibrin clots protecting them from pre
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b280bb0396887d374f3a5c2b310245b9
https://pubmed.ncbi.nlm.nih.gov/31383913
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4
Recombinant factor VIII products and inhibitor development in previously untreated patients with severe haemophilia A: Combined analysis of three studies
Autor: Elena Santagostino, Jenny Goudemand, Kay Martin Hanschmann, Peter William Collins, Thierry Calvez, Daniel P. Hart, Ben Palmer, Peter Volkers, Ella M. van Hardeveld, Hervé Chambost, Charles R. M. Hay, Brigitte Keller-Stanislawski, Rolf Ljung, Virginie Demiguel, Marijke van den Berg
Publikováno v: Haemophilia : the official journal of the World Federation of Hemophilia. 25(3)
INTRODUCTION: Standard treatment of congenital haemophilia A is based on replacement therapy with coagulation factor VIII (FVIII) products. A major complication of FVIII therapy is the occurrence of IgG alloantibodies (inhibitors) that neutralize FVI
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82167c1450474efdc3eb072b054e2b5e
https://pubmed.ncbi.nlm.nih.gov/31066174
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5
Risk of Guillain–Barré syndrome following pandemic influenza A(H1N1) 2009 vaccination in Germany
Autor: Dirk Mentzer, Hans-Peter Hartung, Helmar C. Lehmann, Peter Volkers, Brigitte Keller-Stanislawski, Jürgen Prestel
Publikováno v: Pharmacoepidemiology and Drug Safety
Purpose A prospective, epidemiologic study was conducted to assess whether the 2009 pandemic influenza A(H1N1) vaccination in Germany almost exclusively using an AS03-adjuvanted vaccine (Pandemrix) impacts the risk of Guillain–Barré syndrome (GBS)
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8534cfdf281c59866e3573e721ab406
https://doi.org/10.1002/pds.3638
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6
Identification of Potential Novel Interacting Partners for Coagulation Factor XIII B (FXIII-B) Subunit, a Protein Associated with a Rare Bleeding Disorder
Autor: Mohammad Suhail Akhter, Christoph Reinhart, Johannes Dodt, Andreas Reuter, Sneha Singh, Peter Volkers, Christoph Krettler, Arijit Biswas, Johannes Oldenburg
Publikováno v: International Journal of Molecular Sciences, Vol 20, Iss 11, p 2682 (2019)
International Journal of Molecular Sciences
Volume 20
Issue 11
Coagulation factor XIII (FXIII) is a plasma-circulating heterotetrameric pro-transglutaminase complex that is composed of two catalytic FXIII-A and two protective/regulatory FXIII-B subunits. FXIII acts by forming covalent cross-links within a prefor
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b07187cfa26522f6c60c3ef0aecbee3
https://doi.org/10.3390/ijms20112682
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8
Monitoring bacterial contamination of blood components in Germany: effect of contamination reduction measures
Autor: J. Hoch, C. H. Wirsing von König, W. Däubener, G. Walther-Wenke, Margarethe Heiden, B. Hornei, Peter Volkers
Publikováno v: Vox Sanguinis. 100:359-366
Background and Objectives National guidelines for monitoring bacterial contamination of blood components were introduced in Germany in 1997. Between 1998 and 2002, numerous measures were implemented to prevent bacterial contamination. This study inve
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::44bc2030edf85c0b24349c7ecb4909cc
https://doi.org/10.1111/j.1423-0410.2010.01432.x
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9
Free factor XIII activation peptide (fAP-FXIII) is a regulator of factor XIII activity via factor XIII-B
Autor: Johannes Dodt, Peter Volkers, Ralf Pasternack, Rainer Seitz
Publikováno v: British journal of haematology. 172(3)
In a factor XIIIa (FXIIIa) generation assay with recombinant FXIII-A2 (rFXIII-A2 ) free FXIII activation peptide (fAP-FXII) prolonged the time to peak (TTP) but did not affect the area under the curve (AUC) or concentration at peak (CP). Addition of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c364e5b6c86c6a92fdd99caa84197b1
https://pubmed.ncbi.nlm.nih.gov/26516704
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10
Evaluation of Risk Minimisation Measures for Blood Components - Based on Reporting Rates of Transfusion-Transmitted Reactions (1997-2013)
Autor: Brigitte Keller-Stanislawski, Markus B. Funk, Peter Volkers, A. Lohmann, Margarethe Heiden
Publikováno v: Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie. 42(4)
Background: To assess the impact of safety measures, we compared reporting rates of transfusion-related reactions before and after the implementation of six measures in 1999, 2004, 2006, 2008 and 2009. Methods: Reporting rates of transfusion-transmit
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd7dd5cf5a5abe11392ffae701108146
https://pubmed.ncbi.nlm.nih.gov/26557816
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