Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Peter Vanhoenacker"'
Autor:
C H Brevik, Andrea Hembre Ulsund, Kurt A. Krobert, Kjetil Wessel Andressen, Finn Olav Levy, Peter Vanhoenacker, Ornella Manfra
Publikováno v:
British Journal of Pharmacology
Background and Purpose Classically, ligands of GPCRs have been classified primarily upon their affinity and efficacy to activate a signal transduction pathway. Recent reports indicate that the efficacy of a particular ligand can vary depending on the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb9b242ba9468a2970fc480f50c2a497
https://doi.org/10.1111/bph.13169
https://doi.org/10.1111/bph.13169
Autor:
Guy Haegeman, Kathleen Van Craenenbroeck, Anne Matthys, Béatrice Lintermans, Peter Vanhoenacker
Publikováno v:
Cellular Signalling. 24:1053-1063
The 5-hydroxytryptamine (5-HT)7 receptor is the most recently identified serotonin receptor and is involved in a wide variety of central nervous system (CNS) functions, namely circadian rhythm, REM sleep, depression, thermoregulation, obsessive–com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04556d47c7de90a3fd151cb19eb0547f
https://doi.org/10.1016/j.cellsig.2011.12.027
https://doi.org/10.1016/j.cellsig.2011.12.027
Autor:
Kathleen Van Craenenbroeck, Béatrice Lintermans, Guy Haegeman, Kjetil Wessel Andressen, Peter Vanhoenacker, Finn Olav Levy, Evelien Gellynck
Publikováno v:
FEBS Journal. 279:1994-2003
The 5-hydroxytryptamine (5-HT)7(a) receptor is a G-protein-coupled receptor critically involved in human psychiatric and neurological disorders. In the present study, we evaluate the presence and the functional role of N-glycosylation of the human 5-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cfa73618a3ef4f66310dc7247893439c
https://doi.org/10.1111/j.1742-4658.2012.08581.x
https://doi.org/10.1111/j.1742-4658.2012.08581.x
Autor:
Bart Devreese, Kamila Skieterska, Peter Vanhoenacker, Griet Debyser, Béatrice Lintermans, Anneleen Spooren, Bart Samyn, Kathleen Van Craenenbroeck, Urszula Wojda, Guy Haegeman, Katarzyna Debowska, Pieter Rondou, Linda Vermeulen
Publikováno v:
Cellular Signalling. 22:600-609
Dopamine receptors are G-protein-coupled receptors involved in the control of motivation, learning, and fine-tuning of motor movement, as well as modulation of neuroendocrine signalling. Stimulation of G-protein-coupled receptors normally results in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4bbeb5f57c4d048bad391881596d69c
https://doi.org/10.1016/j.cellsig.2009.11.013
https://doi.org/10.1016/j.cellsig.2009.11.013
Autor:
Laenen Koen Leander Maria, Kathleen Van Craenenbroeck, Kim De Martelaere, Béatrice Lintermans, Kjetil Wessel Andressen, Anne Matthys, Guy Haegeman, Peter Vanhoenacker, Evelien Gellynck, Finn Olav Levy
Publikováno v:
Gene. 426:23-31
The serotonin (5-HT) 5-HT(7) receptors are expressed in both the central nervous system and in peripheral tissues. Receptor distribution studies and pharmacological studies have established that 5-HT(7) receptors play an important role in the control
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99ab9d159f98540ee59fc6c8cd66bb88
https://doi.org/10.1016/j.gene.2008.08.011
https://doi.org/10.1016/j.gene.2008.08.011
Publikováno v:
Journal of Biological Chemistry. 283:11083-11096
Dopamine receptors belong to the superfamily of G-protein-coupled receptors and are subdivided into D1-type (D1 and D5) and D2-type (D2, D3, and D4) receptors. The D4 receptor has a remarkable polymorphism in its third intracellular loop, which is un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8b037066c47a9a6fd80ed92de773e56
https://doi.org/10.1074/jbc.m708473200
https://doi.org/10.1074/jbc.m708473200
Publikováno v:
Cellular Signalling. 19:278-288
Three 5-HT7 receptor isoforms are expressed in rat and man, which differ in the amino acid sequence of their C-terminus. Thus far, no changes have been observed in the pharmacological profile of all three isoforms. To further elucidate the signal tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfbc3bf80128994eebfbe03a89824a3c
https://doi.org/10.1016/j.cellsig.2006.06.012
https://doi.org/10.1016/j.cellsig.2006.06.012
Publikováno v:
FEBS Letters. 555:489-494
Episomal vectors, described for efficient and regulated expression of heterologous proteins in mammalian cells, have the advantage that they persist in multiple copies in the cell without integrating into the chromosome. To efficiently express hetero
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab6f50966ff6523f9bfbbc7ad84d0b3f
https://doi.org/10.1016/s0014-5793(03)01311-5
https://doi.org/10.1016/s0014-5793(03)01311-5
Publikováno v:
European Journal of Neuroscience. 14:968-976
Establishing a stable cell line that expresses a particular protein of interest is often a laborious and time-consuming experience. With constitutive expression systems, a gradual loss of the highly expressing clones over a given time span and/or a s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::827e829198f650d10fa401759ffec8e6
https://doi.org/10.1046/j.0953-816x.2001.01719.x
https://doi.org/10.1046/j.0953-816x.2001.01719.x
Publikováno v:
Trends in Pharmacological Sciences. 21:70-77
Identification of three splice variants of the 5-HT7 receptor suggests a possible diversity in 5-HT7 receptor action. Indeed, 5-HT7 receptors have been implicated in the pathophysiology of several disorders; they play a role in smooth muscle relaxati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15939e4f3424ed4d8989cdab968b927e
https://doi.org/10.1016/s0165-6147(99)01432-7
https://doi.org/10.1016/s0165-6147(99)01432-7