Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Peter V. Pallai"'
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 12:775-778
Novel phenol bis-Mannich adducts were identified as IL-2 expression inhibitors in a T cell proliferation screening assay. Analogues of the lead compound were prepared through parallel synthesis and a highly selective IL-2 inhibitor was discovered tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4115d7a0a2094b4a54f60327fc7fc0a
https://doi.org/10.1016/s0960-894x(02)00011-2
https://doi.org/10.1016/s0960-894x(02)00011-2
Autor:
Peter V. Pallai, Malcolm J. McGregor
Publikováno v:
Journal of Chemical Information and Computer Sciences. 37:443-448
An analysis of chemical structures from several commercially available libraries of compounds is presented with a view of acquiring compounds for screening. The Jarvis−Patrick clustering method has been applied, using the MDL “keys” as structur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c9744f5a0b3a74d7bb1ba044d92ad453
https://doi.org/10.1021/ci960151e
https://doi.org/10.1021/ci960151e
Autor:
Peter V. Pallai, Ariamala Gopalsamy
Publikováno v:
Tetrahedron Letters. 38:907-910
The Doebner quinoline synthesis has been adopted to solid phase. Acylation of an amino acid coupled to the Rink polystyrene resin with pyruvyl chloride afforded the immobilized amide 11 . Further reaction of 11 with the preformed Schiff's base 12 or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4bc03b406d7ddd394b663a262b0972ce
https://doi.org/10.1016/s0040-4039(96)02456-2
https://doi.org/10.1016/s0040-4039(96)02456-2
Autor:
Azis Kongsjahju, Marie-Rose van Schravendijk, Ariamala Gopalsamy, Kristin A. Gordon, Kevin Daniels, Raymond J. Patch, Huai Gao, Paul J. Kowalczyk, Peter V. Pallai, Zhan Shi, John C. Roberts
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 6:2983-2988
A series of lipophilic bis-arylsulfonates was synthesized and evaluated as potential inhibitors of the CD4-gp120 interaction. Structure-activity studies suggested a direct relationship between the nature and extent of lipophilicity and inhibitory pot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::edf3169fcc89251c399d7ebc10f53a51
https://doi.org/10.1016/s0960-894x(96)00552-5
https://doi.org/10.1016/s0960-894x(96)00552-5
Publikováno v:
Tetrahedron Letters. 36:691-694
A novel design and asymmetric synthesis of two-residue mimics is presented as part of a modular approach to beta strand mimicry.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d2fb220a521daedcb4f4d085a303b20
https://doi.org/10.1016/0040-4039(94)02354-e
https://doi.org/10.1016/0040-4039(94)02354-e
Publikováno v:
ChemInform. 27
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::16d4dac5763926fb3669f689dcf178c0
https://doi.org/10.1002/chin.199645235
https://doi.org/10.1002/chin.199645235
Autor:
Malcolm J. McGregor, Peter V. Pallai
Publikováno v:
ChemInform. 28
An analysis of chemical structures from several commercially available libraries of compounds is presented with a view of acquiring compounds for screening. The Jarvis−Patrick clustering method has been applied, using the MDL “keys” as structur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a843dc81796b3d3ca3724d2548804e7
https://doi.org/10.1002/chin.199737282
https://doi.org/10.1002/chin.199737282
Publikováno v:
ChemInform. 33
Novel phenol bis-Mannich adducts were identified as IL-2 expression inhibitors in a T cell proliferation screening assay. Analogues of the lead compound were prepared through parallel synthesis and a highly selective IL-2 inhibitor was discovered tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f68b18f51ab81e8b82f9a0affc1308d7
https://doi.org/10.1002/chin.200225148
https://doi.org/10.1002/chin.200225148
Autor:
Thomas W. Seng, David J. Hall, Griffith D. Parks, Ann C. Palmenberg, Richard H. Ingraham, Peter V. Pallai
Publikováno v:
Virology. 190:754-762
The primary 2A/2B cleavage within cardiovirus polyprotein was examined by construction of cDNA plasmids which linked fragments from the P2 region of encephalomyocarditis virus (EMCV) and Mengovirus genomes to the EMCV 5' nontranslated region. When RN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::706f627709a66523c249caf6fd790004
https://doi.org/10.1016/0042-6822(92)90913-a
https://doi.org/10.1016/0042-6822(92)90913-a
Publikováno v:
The Journal of organic chemistry. 61(13)
We describe the asymmetric synthesis of non-peptidic compounds that feature rigid backbone conformations and present various side-chain functions. The key step in the synthesis of these compounds is the C-acylation of an appropriate ketone with a sui
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c090c4edf4f18b43a4cb300c3d2af9f
https://pubmed.ncbi.nlm.nih.gov/11667349
https://pubmed.ncbi.nlm.nih.gov/11667349