Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Peter U. Fischer"'
Autor:
Young-Jun Choi, Kerstin Fischer, Aboulaye Méité, Benjamin G. Koudou, Peter U. Fischer, Makedonka Mitreva
Publikováno v:
EBioMedicine, Vol 105, Iss , Pp 105188- (2024)
Summary: Background: The Global Program to Eliminate Lymphatic Filariasis (GPELF) is the largest public health program based on mass drug administration (MDA). Despite decades of MDA, ongoing transmission in some countries remains a challenge. To opt
Externí odkaz:
https://doaj.org/article/4f67fc9d6387489a8b6720bd977c7937
Autor:
Lucia S. Di Maggio, Kerstin Fischer, Devyn Yates, Kurt C. Curtis, Bruce A. Rosa, John Martin, Petra Erdmann-Gilmore, Robert S. W. Sprung, Makedonka Mitreva, R. Reid Townsend, Gary J. Weil, Peter U. Fischer
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Paragonimiasis is a zoonotic, food-borne trematode infection that affects 21 million people globally. Trematodes interact with their hosts via extracellular vesicles (EV) that carry protein and RNA cargo. We analyzed EV in excretory-secretor
Externí odkaz:
https://doaj.org/article/ad1736ee439c48df8c879adcd35181d2
Autor:
Devyn Yates, Lucia S. Di Maggio, Bruce A. Rosa, Robert W. Sprung, Petra Erdmann-Gilmore, R. Reid Townsend, Philip J. Budge, Joseph Kamgno, Makedonka Mitreva, Gary J. Weil, Peter U. Fischer
Publikováno v:
Frontiers in Parasitology, Vol 2 (2023)
BackgroundImproved diagnostic tools are needed for detecting active filarial infections in humans. Tests are available that detect adult W. bancrofti circulating filarial antigen, but there are no sensitive and specific biomarker tests for brugian fi
Externí odkaz:
https://doaj.org/article/664a178a13a740d4ba347c475f01d58d
Autor:
Uwem F. Ekpo, Obiora A. Eneanya, Edith N. Nwankwo, Islamiat Y. Soneye, Gary J. Weil, Peter U. Fischer, Obioma C. Nwaorgu
Publikováno v:
BMC Infectious Diseases, Vol 22, Iss 1, Pp 1-6 (2022)
Abstract Background Onchocerciasis is endemic in most local government areas (LGAs) in Enugu and Ogun states. Most meso- and hyper-endemic LGAs have received many rounds of ivermectin mass drug administration (MDA). This study aimed to determine the
Externí odkaz:
https://doaj.org/article/f1c096a0e0d44745b9a3d9c1aa32e245
Autor:
Kerstin Fischer, Bettina Dubben, Linda B. Debrah, Janina M. Kuehlwein, Arcangelo Ricchiuto, Alexander Y. Debrah, Achim Hoerauf, Gary J. Weil, Peter U. Fischer, Ute Klarmann-Schulz
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
BackgroundNovel drugs or drug combinations that kill or permanently sterilize adult Onchocerca volvulus worms would be very helpful for treatment and elimination of onchocerciasis. In absence of a reliable biomarker for viable adult worms, histopatho
Externí odkaz:
https://doaj.org/article/6e763577f07a43e4ae6e7480447301ca
Autor:
Sarah E. Greene, Kerstin Fischer, Young-Jun Choi, Kurt C. Curtis, Philip J. Budge, Makedonka Mitreva, Christopher L. King, Peter U. Fischer, Gary J. Weil
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 16, Iss 5 (2022)
Background Lymphatic filariasis (LF) is a neglected tropical disease caused by the filarial nematodes Wuchereria bancrofti, Brugia malayi and Brugia timori. The Global Program to Eliminate LF uses mass drug administration (MDA) of anti-filarial drugs
Externí odkaz:
https://doaj.org/article/3a4ecc9baf734cc182b6fde155c18148
Autor:
Liana Beld, Hyeim Jung, Christina A. Bulman, Bruce A. Rosa, Peter U. Fischer, James W. Janetka, Sara Lustigman, Judy A. Sakanari, Makedonka Mitreva
Publikováno v:
Pathogens, Vol 11, Iss 6, p 707 (2022)
The current treatments for lymphatic filariasis and onchocerciasis do not effectively kill the adult parasitic nematodes, allowing these chronic and debilitating diseases to persist in millions of people. Thus, the discovery of new drugs with macrofi
Externí odkaz:
https://doaj.org/article/f78355ca91a249b3abce3ec41466da4c
Autor:
Bruce A. Rosa, Caroline Snowden, John Martin, Kerstin Fischer, Jonah Kupritz, Ethiopia Beshah, Taniawati Supali, Lincoln Gankpala, Peter U. Fischer, Joseph F. Urban, Makedonka Mitreva
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
The human whipworm Trichuris trichiura infects 289 million people worldwide, resulting in substantial morbidity. Whipworm infections are difficult to treat due to low cure rates and high reinfection rates. Interactions between whipworm and its host
Externí odkaz:
https://doaj.org/article/24be61b9bd054c28aea56a464fdc5224
Autor:
Kerstin Fischer, Abakar Gankpala, Lincoln Gankpala, Fatorma K. Bolay, Kurt C. Curtis, Gary J. Weil, Peter U. Fischer
Publikováno v:
Emerging Infectious Diseases, Vol 24, Iss 8, Pp 1551-1554 (2018)
We examined human stool samples from Liberia for soil-transmitted helminth ova by Kato-Katz smear and by quantitative PCR. Twenty-five samples were positive for Trichuris trichiura by smear but negative by quantitative PCR. Reexamination of samples s
Externí odkaz:
https://doaj.org/article/d88712e1d9da409fb0ca1c971d3854fc
Autor:
Bruce A. Rosa, Taniawati Supali, Lincoln Gankpala, Yenny Djuardi, Erliyani Sartono, Yanjiao Zhou, Kerstin Fischer, John Martin, Rahul Tyagi, Fatorma K. Bolay, Peter U. Fischer, Maria Yazdanbakhsh, Makedonka Mitreva
Publikováno v:
Microbiome, Vol 6, Iss 1, Pp 1-19 (2018)
Abstract Background The human intestine and its microbiota is the most common infection site for soil-transmitted helminths (STHs), which affect the well-being of ~ 1.5 billion people worldwide. The complex cross-kingdom interactions are not well und
Externí odkaz:
https://doaj.org/article/966fe11c1ea64f83b7363d58e28c3af5