Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Peter T. Peachell"'
Publikováno v:
Journal of Immunotoxicology, Vol 14, Iss 1, Pp 60-65 (2017)
As part of the intracellular processes leading to mast cell and basophil activation, phosphorylation of key substrates is likely to be important. These processes, mediated by phosphatases, are responsible for regulating phosphorylation. The aim of th
Externí odkaz:
https://doaj.org/article/484b1a0d4c02436e939edeef6a65bea4
Publikováno v:
European Journal of Pharmacology. 837:38-44
The diverse effects of histamine are mediated by discrete histamine receptors. The principal repository of histamine in the body is the mast cell. However, the effects of histamine on mast cells, especially those of human origin, have not been fully
Publikováno v:
European Journal of Pharmacology. 819:225-232
Mast cells are an exceptionally rich source of prostaglandin D2 (PGD2). PGD2 is pro-inflammatory and can cause bronchoconstriction. The enzyme cyclooxygenase (COX) is central to the generation of prostanoids such as PGD2. Non-steroidal anti-inflammat
Publikováno v:
Clinical & Experimental Allergy. 47:1022-1031
SummaryBackground Clinical desensitization and oral food immunotherapy are therapeutic interventions that allow individuals who react adversely to an allergen (drug or food) to be made tolerant to the allergen. However, tolerance is brief, and allerg
Publikováno v:
Journal of Immunotoxicology, Vol 14, Iss 1, Pp 60-65 (2017)
As part of the intracellular processes leading to mast cell and basophil activation, phosphorylation of key substrates is likely to be important. These processes, mediated by phosphatases, are responsible for regulating phosphorylation. The aim of th
Publikováno v:
European Journal of Pharmacology. 793:49-55
The principal mechanism by which bronchodilator β-adrenoceptor agonists act is to relax airways smooth muscle although they may also be anti-inflammatory. However, the extent of anti-inflammatory activity and the cell types affected by these agonist
Autor:
Linda J Kay, Helen M. Marriott, Martin A. Bewley, Yiwen Yao, Sharonjit K Gill, Peter T. Peachell
Publikováno v:
British Journal of Pharmacology. 173:3099-3109
Background and Purpose PGE2 inhibits cytokine generation from human lung macrophages. However, the EP receptor that mediates this beneficial anti-inflammatory effect of PGE2 has not been defined. The aim of this study was to identify the EP receptor
Publikováno v:
European journal of pharmacology. 837
The diverse effects of histamine are mediated by discrete histamine receptors. The principal repository of histamine in the body is the mast cell. However, the effects of histamine on mast cells, especially those of human origin, have not been fully
Autor:
Joakim S. Dahlin, Mamdoh Al-Ameri, Sven-Erik Dahlén, Avinash Ravindran, Peter T. Peachell, Mikael Adner, Elin Rönnberg, Ann-Charlotte Orre, Jesper Säfholm, Luca Mazzurana, Jenny Mjösberg, Gunnar Nilsson
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Frontiers in Immunology
Frontiers in Immunology
Background: Mast cells are tissue-resident inflammatory cells defined by their high granularity and surface expression of the high-affinity IgE receptor, Fc + RI, and CD117/KIT, the receptor for stem cell factor (SCF). There is a considerable heterog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad79911eda53b4c5b733480d151c1548
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-367035
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-367035
Publikováno v:
European journal of pharmacology. 819
Mast cells are an exceptionally rich source of prostaglandin D