Zobrazeno 1 - 10
of 142
pro vyhledávání: '"Peter T. Northcote"'
Autor:
Mathew A. Storey, Sarah K. Andreassend, Joe Bracegirdle, Alistair Brown, Robert A. Keyzers, David F. Ackerley, Peter T. Northcote, Jeremy G. Owen
Publikováno v:
mBio, Vol 11, Iss 2 (2020)
ABSTRACT Marine sponges have been a prolific source of unique bioactive compounds that are presumed to act as a deterrent to predation. Many of these compounds have potential therapeutic applications; however, the lack of efficient and sustainable sy
Externí odkaz:
https://doaj.org/article/94c3f8add06a48ba9ee2fb71c7a960c2
Publikováno v:
Molecules, Vol 26, Iss 15, p 4534 (2021)
The islands of the South Pacific Ocean have been in the limelight for natural product biodiscovery, due to their unique and pristine tropical waters and environment. The Kingdom of Tonga is an archipelago in the central Indo-Pacific Ocean, consisting
Externí odkaz:
https://doaj.org/article/9052f3c233bd48998164b57173787071
Autor:
Michael V. Berridge, John H. Miller, Anne C. La Flamme, Peter T. Northcote, David O’Sullivan, Praneta Joshi, Dora C. Leahy, An S. Tan, Kirsten J. Meyer, A. Jonathan Singh, Alanna Cameron
Publikováno v:
Marine Drugs, Vol 10, Iss 4, Pp 900-917 (2012)
Mycothiazole, a polyketide metabolite isolated from the marine sponge Cacospongia mycofijiensis, is a potent inhibitor of metabolic activity and mitochondrial electron transport chain complex I in sensitive cells, but other cells are relatively insen
Externí odkaz:
https://doaj.org/article/96e64ce3ad3d4736a9817df7f2910990
Publikováno v:
Marine Drugs, Vol 8, Iss 4, Pp 1059-1079 (2010)
Marine sponges are an excellent source of bioactive secondary metabolites with potential therapeutic value in the treatment of diseases. One group of compounds of particular interest is the microtubule-stabilizing agents, the most well-known compound
Externí odkaz:
https://doaj.org/article/e35948f05c7c48b7a833ba5361a3520a
Autor:
John H. Miller, Paraskevi Giannakakou, Ernest Hamel, Peter T. Northcote, Bronwyn Kivell, Pisana Rawson, Janet Crawford, Ada Gjyrezi, Ariane Chan, Daniel Escuin, Aurora O'Brate, Anja Wilmes, Arun Kanakkanthara
Supplementary Tables 1-4, Figures 1-4 from Peloruside- and Laulimalide-Resistant Human Ovarian Carcinoma Cells Have βI-Tubulin Mutations and Altered Expression of βII- and βIII-Tubulin Isotypes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::105051d1cf8ece903dfe8ef6ac184c5b
https://doi.org/10.1158/1535-7163.22497106.v1
https://doi.org/10.1158/1535-7163.22497106.v1
Publikováno v:
Drug and Drug Abuse. :1-5
The hamigerans are diterpenoid secondary metabolites isolated from the New Zealand marine sponge Hamigera tarangaensis. Of all the hamigerans that have been isolated and characterised at Victoria University of Wellington, hamigeran G showed the most
Autor:
Rose M. A. Gordon, Robert A. Keyzers, John H. Miller, Peter T. Northcote, Kainat Hira, Taitusi Taufa, Muhammad Ali Hashmi, Matthias Lein, Jane Fromont
Publikováno v:
Tetrahedron Letters. 60:1825-1829
Pyrroloquinoline alkaloids are well known bioactive metabolites commonly found from latrunculiid sponges. Two new pyrroloquinoline alkaloids, 6-bromodamirone B (1) and makaluvamine W (2), were isolated from the Tongan sponge Strongylodesma tongaensis
Publikováno v:
Steroids. 141:9-13
NMR-directed investigation of the two sponge association between Stelletta crater and Desmacella dendyi has resulted in the isolation of two new members of the rare 4-methylidene class of sterols. Craterol A (1) and B (2) represent the first examples
Autor:
Victoria H. Woolner, Rose M. A. Gordon, Peter T. Northcote, Robert A. Keyzers, Matthias Lein, John H. Miller
Publikováno v:
Journal of Natural Products. 81:2446-2454
A detailed examination of the red alga Callophycus serratus collected in Tonga led to the isolation of six new halogenated meroditerpenoids: callophycol C (1), callophycoic acid I (2), iodocallophycols E (3) and F (4), iodocallophycoic acid B (5), an