Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Peter T. Mayer"'
Publikováno v:
Biochemistry. 42:1624-1636
Passive peptide transport across lipid membranes is governed by the energetics of partitioning into the ordered chain interior coupled with the rate of diffusion across this region. A hydrophobicity scale for peptide transfer into the barrier region
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10187898cae496f63032157250a88a0f
https://doi.org/10.1021/bi026701l
https://doi.org/10.1021/bi026701l
Publikováno v:
Journal of Pharmaceutical Sciences. 85:773-780
The crystal polymorphism of Abbott-79175, a potent second-generation 5-lipoxygenase inhibitor, has been studied. Crystallization from an ethyl acetate/heptane system in which moisture content was not controlled and from an ethanol/water system produc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a140e6514084e1497abf816547ed53a
https://doi.org/10.1021/js950055c
https://doi.org/10.1021/js950055c
Autor:
Jay S. Trivedi, Peter T. Mayer, Armin H. Gerhardt, Robert J. Schilling, James J. Fort, Yihong Qiu, Jacqueline Briskin
Publikováno v:
Drug development and industrial pharmacy. 28(3)
ABT-761 is a 5-lipoxygenase inhibitor developed for the treatment of asthma. The present study was undertaken to evaluate different crystal forms of ABT-761 and their impact on in vitro and in vivo performance in capsule formulations. Two crystal for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de3d0fddcadea3d8b951e31214620106
https://pubmed.ncbi.nlm.nih.gov/12026221
https://pubmed.ncbi.nlm.nih.gov/12026221
Autor:
Peter T. Mayer, Bradley D. Anderson
Publikováno v:
Journal of pharmaceutical sciences. 91(3)
The barrier domain solubility-diffusion theory of lipid bilayer permeability relates the permeability coefficient (P(m)) to the solute's partition coefficient (PC(barrier/w)) and diffusion coefficient (D(barrier)) in the ordered chain region of the b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bd85fb1a6aed30ba35a3e77b6b34fff
https://pubmed.ncbi.nlm.nih.gov/11920749
https://pubmed.ncbi.nlm.nih.gov/11920749
Publikováno v:
AAPS pharmSci. 2(2)
To explore the independence of functional group contributions to permeability of nonelectrolytes across egg lecithin bilayers, the transport rates were measured of a series of alpha-substituted p-methylhippuric acids (-H, -Cl, -OCH3, -CN, -OH, -COOH,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12067402fcecafcfa282b5cacf1dd0cc
https://pubmed.ncbi.nlm.nih.gov/11741230
https://pubmed.ncbi.nlm.nih.gov/11741230