Zobrazeno 1 - 10 of 20 pro vyhledávání: '"Peter T, McKenney"'
1
Acidification-dependent suppression ofC. difficileby enterococci in vitro
Autor: Holly R. Smith, Alicia K. Wood, Angus Johnson, Avi Z. Stern, Zainab Sikander, Lesly-Hannah Gutierrez, Addelis A. Agosto, Peter T. McKenney
Clostridioides difficileand Vancomycin-resistantEnterococcus faecium(VRE) are commonly co-isolated from hospitalized patients. We sought to developin vitroco-culture systems to identify interactions and study biofilm formation by these two opportunis
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ab1f6cb44ae42afa30b6702602d9e536
https://doi.org/10.1101/2023.05.16.541032
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2
Bacterial metabolism of bile acids promotes generation of peripheral regulatory T cells
Autor: Krishna Kadaveru, John Hambor, Clarissa Campbell, Alexander Y. Rudensky, Cheryl Mai, Daniel Konstantinovsky, Peter T. McKenney, Ruben J. Ramos, Olga I Isaeva, Chun-Jun Guo, Michail Schizas, Justin R. Cross, Jacob Verter, Wen-Bing Jin, Sara Violante
Publikováno v: Nature. 581:475-479
Intestinal health relies on the immunosuppressive activity of CD4+ regulatory T (Treg) cells1. Expression of the transcription factor Foxp3 defines this lineage, and can be induced extrathymically by dietary or commensal-derived antigens in a process
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9ba5447a9b51cd120c59b91735e0d748
https://doi.org/10.1038/s41586-020-2193-0
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4
Diversification and Evolution of Vancomycin-Resistant Enterococcus faecium during Intestinal Domination
Autor: Peter T. McKenney, Joao B. Xavier, Eric G. Pamer, Deepti Mathur, Krista Dubin, Ying Taur, Eric R. Littmann, Jonathan U. Peled, Marcel R.M. van den Brink, Bradford P. Taylor
Publikováno v: Infection and Immunity
Vancomycin-resistant Enterococcus faecium (VRE) is a leading cause of hospital-acquired infections. This is particularly true in immunocompromised patients, where the damage to the microbiota caused by antibiotics can lead to VRE domination of the in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::856501c0bd10e924a78dbcb795c042e0
http://europepmc.org/articles/PMC6589067
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5
Intestinal bile acids induce a morphotype switch in vancomycin-resistant enterococcus that facilitates intestinal colonization
Autor: Peter T. McKenney, Eric G. Pamer, Jinyuan Yan, Julien Vaubourgeix, Joao B. Xavier, Daniel Dannaoui, Simone Becattini, Peter J. Larson, Andrew Motzer, Sho Fujisawa, Nina Lampen
Publikováno v: 705.e5
Cell Host Microbe
Summary Vancomycin-resistant Enterococcus (VRE) are highly antibiotic-resistant and readily transmissible pathogens that cause severe infections in hospitalized patients. We discovered that lithocholic acid (LCA), a secondary bile acid prevalent in t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d97ef05c99ad93d75ff2989d0c66830
http://hdl.handle.net/10044/1/71159
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6
Clostridium difficile colitis: pathogenesis and host defence
Autor: Eric G. Pamer, Peter T. McKenney, Michael C. Abt
Publikováno v: Nature Reviews Microbiology. 14:609-620
Clostridium difficile is a major cause of intestinal infection and diarrhoea in individuals following antibiotic treatment. Recent studies have begun to elucidate the mechanisms that induce spore formation and germination and have determined the role
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0f88743d36a97f7501d2e125a9a3b21
https://doi.org/10.1038/nrmicro.2016.108
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7
From Hype to Hope: The Gut Microbiota in Enteric Infectious Disease
Autor: Eric G. Pamer, Peter T. McKenney
Publikováno v: Cell. 163(6):1326-1332
One of the clearest functions of the gut microbiota in humans is resistance to colonization by enteric bacterial pathogens. Reconstitution of the microbiota offers an exciting therapeutic approach, but great challenges must be overcome.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89bae99cc33868986f2b236a31240192
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8
Bile Acid Induced Morphotype Switch Mediates Intestinal Colonization in Vancomycin Resistant Enterococcus
Autor: Daniel Dannaoui, Andrew Motzer, Simone Becattini, Eric G. Pamer, Joao B. Xavier, Peter T. McKenney, Nina Lampen, Peter J. Larson, Jinyuan Yan, Julien Vaubourgeix
Publikováno v: SSRN Electronic Journal.
Vancomycin resistant Enterococcus (VRE) is a highly antibiotic-resistant and readily transmissible pathogen that causes severe infections in hospitalized patients. We discovered that lithocholic acid (LCA), a secondary bile acid prevalent in the cecu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9fd5e8343ade5f19f02c93254d982373
https://doi.org/10.2139/ssrn.3155719
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9
Single-Cell Map of Diverse Immune Phenotypes in the Breast Tumor Microenvironment
Autor: Kristy Choi, Rachel M. Fromme, Andrew E. Cornish, Phuong Dao, Alexander Y. Rudensky, Juozas Nainys, Krishna Kadaveru, George Plitas, Linas Mazutis, Peter T. McKenney, Sandhya Prabhakaran, Catherine Konopacki, Manu Setty, Elham Azizi, Ruby C. Wasti, Vaidotas Kiseliovas, Kenmin Wu, Dana Pe'er, Ambrose J. Carr
Publikováno v: Cell. 174(5)
Knowledge of immune cell phenotypes in the tumor microenvironment is essential for understanding mechanisms of cancer progression and immunotherapy response. We profiled 45,000 immune cells from eight breast carcinomas, as well as matched normal brea
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f38ec6a5f2a58237ccba5bdc79bce16
https://pubmed.ncbi.nlm.nih.gov/29961579
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