Zobrazeno 1 - 10
of 304
pro vyhledávání: '"Peter T, Donnan"'
Autor:
Morven Miller, Lisa McCann, Liane Lewis, Christine Miaskowski, Emma Ream, Andrew Darley, Jenny Harris, Grigorios Kotronoulas, Geir V Berg, Simone Lubowitzki, Jo Armes, Elizabeth Patiraki, Eileen Furlong, Patricia Fox, Alexander Gaiger, Antonella Cardone, Dawn Orr, Adrian Flowerday, Stylianos Katsaragakis, Simon Skene, Margaret Moore, Paul McCrone, Nicosha De Souza, Peter T Donnan, Roma Maguire
Publikováno v:
Journal of Medical Internet Research, Vol 26, p e49309 (2024)
BackgroundInterest in the application of predictive risk models (PRMs) in health care to identify people most likely to experience disease and treatment-related complications is increasing. In cancer care, these techniques are focused primarily on th
Externí odkaz:
https://doaj.org/article/ce2259cbe6d34f888764295adf13d6b4
Publikováno v:
BMJ Open, Vol 14, Iss 4 (2024)
Objectives This study aims to examine community antibiotic prescribing across a complete geographical area for people with a positive COVID-19 test across three pandemic waves, and to examine health and demographic factors associated with antibiotic
Externí odkaz:
https://doaj.org/article/bcb036b429954932bacd0b316b8fed12
Autor:
Alvin Shrestha, Tufail Bashir, Marcus Achison, Simon Adamson, Asangaedem Akpan, Terry Aspray, Alison Avenell, Margaret M Band, Louise A Burton, Vera Cvoro, Peter T Donnan, Gordon W Duncan, Jacob George, Adam L Gordon, Celia L Gregson, Adrian Hapca, Cheryl Hume, Thomas A Jackson, Simon Kerr, Alixe Kilgour, Tahir Masud, Andrew McKenzie, Emma McKenzie, Harnish Patel, Kristina Pilvinyte, Helen C Roberts, Avan A Sayer, Christos Rossios, Karen T Smith, Roy L Soiza, Claire J Steves, Allan D Struthers, Divya Tiwari, Julie Whitney, Miles D Witham, Paul R Kemp
Publikováno v:
PLoS ONE, Vol 19, Iss 8, p e0307268 (2024)
IntroductionUnderstanding genetic contributors to sarcopenia (age-related loss of muscle strength and mass) is key to finding effective therapies. Variants of the bradykinin receptor 2 (BDKRB2) have been linked to athletic and muscle performance. The
Externí odkaz:
https://doaj.org/article/729f9642b39144fe86a84ce912c50d84
Publikováno v:
BMC Cardiovascular Disorders, Vol 23, Iss 1, Pp 1-12 (2023)
Abstract Background Prediction of lifetime cardiovascular disease (CVD) risk is recommended in many clinical guidelines, but lifetime risk models are rarely externally validated. The aim of this study was to externally validate the QRiskLifetime inci
Externí odkaz:
https://doaj.org/article/e9724ac205724de384c175f8e0a78ae9
Publikováno v:
BMC Medicine, Vol 20, Iss 1, Pp 1-17 (2022)
Abstract Background Acute kidney injury (AKI) is common and associated with adverse outcomes as well as important healthcare costs. However, evidence examining the epidemiology of acute kidney disease (AKD)—recently defined as AKI persisting betwee
Externí odkaz:
https://doaj.org/article/aed775bf12d44fcaa7b96a70cbb1da28
Community prescribing trends and prevalence in the last year of life, for people who die from cancer
Publikováno v:
BMC Palliative Care, Vol 21, Iss 1, Pp 1-13 (2022)
Abstract Background People who die from cancer (‘cancer decedents’) may latterly experience unpleasant and distressing symptoms. Prescribing medication for pain and symptom control is essential for good-quality palliative care; however, such prov
Externí odkaz:
https://doaj.org/article/e5127b7a16a847578778ba8becdb2a05
Publikováno v:
BMC Medicine, Vol 20, Iss 1, Pp 1-12 (2022)
Abstract Background Recommended cardiovascular disease (CVD) prediction tools do not account for competing mortality risk and over-predict incident CVD in older and multimorbid people. The aim of this study was to derive and validate a competing risk
Externí odkaz:
https://doaj.org/article/49a23e9edbbe40e3b058e8e62e1599e7
Autor:
The LACE study group, Marcus Achison, Simon Adamson, Asangaedem Akpan, Terry Aspray, Alison Avenell, Margaret M. Band, Tufail Bashir, Louise A. Burton, Vera Cvoro, Peter T. Donnan, Gordon W. Duncan, Jacob George, Adam L. Gordon, Celia L. Gregson, Adrian Hapca, Emily Henderson, Cheryl Hume, Thomas A. Jackson, Paul Kemp, Simon Kerr, Alixe Kilgour, Veronica Lyell, Tahir Masud, Andrew McKenzie, Emma McKenzie, Harnish Patel, Kristina Pilvinyte, Helen C. Roberts, Christos Rossios, Avan A. Sayer, Karen T. Smith, Roy L. Soiza, Claire J. Steves, Allan D. Struthers, Deepa Sumukadas, Divya Tiwari, Julie Whitney, Miles D. Witham
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 13, Iss 2, Pp 858-871 (2022)
Abstract Background This trial aimed to determine the efficacy of leucine and/or perindopril in improving physical function in older people with sarcopenia. Methods Placebo‐controlled, parallel group, double‐blind, randomized two‐by‐two facto
Externí odkaz:
https://doaj.org/article/5f34d75a32554bc08ecdb7f05da3b12d
Autor:
Tufail Bashir, Marcus Achison, Simon Adamson, Asangaedem Akpan, Terry Aspray, Alison Avenell, Margaret M Band, Louise A Burton, Vera Cvoro, Peter T Donnan, Gordon W Duncan, Jacob George, Adam L Gordon, Celia L Gregson, Adrian Hapca, Cheryl Hume, Thomas A Jackson, Simon Kerr, Alixe Kilgour, Tahir Masud, Andrew McKenzie, Emma McKenzie, Harnish Patel, Kristina Pilvinyte, Helen C Roberts, Christos Rossios, Avan A Sayer, Karen T Smith, Roy L Soiza, Claire J Steves, Allan D Struthers, Divya Tiwari, Julie Whitney, Miles D Witham, Paul R Kemp
Publikováno v:
PLoS ONE, Vol 18, Iss 11, p e0294330 (2023)
BackgroundAgeing is associated with changes in body composition including an overall reduction in muscle mass and a proportionate increase in fat mass. Sarcopenia is characterised by losses in both muscle mass and strength. Body composition and muscl
Externí odkaz:
https://doaj.org/article/c30fb2aff4ea4c5a9943bf38e3bcd800
Autor:
Christos Rossios, Tufail Bashir, Marcus Achison, Simon Adamson, Asangaedem Akpan, Terry Aspray, Alison Avenell, Margaret M Band, Louise A Burton, Vera Cvoro, Peter T Donnan, Gordon W Duncan, Jacob George, Adam L Gordon, Celia L Gregson, Adrian Hapca, Cheryl Hume, Thomas A Jackson, Simon Kerr, Alixe Kilgour, Tahir Masud, Andrew McKenzie, Emma McKenzie, Harnish Patel, Kristina Pilvinyte, Helen C Roberts, Avan A Sayer, Karen T Smith, Roy L Soiza, Claire J Steves, Allan D Struthers, Divya Tiwari, Julie Whitney, Miles D Witham, Paul R Kemp
Publikováno v:
PLoS ONE, Vol 18, Iss 10, p e0292402 (2023)
BackgroundAngiotensin II (AII), has been suggested to promote muscle loss. Reducing AII synthesis, by inhibiting angiotensin converting enzyme (ACE) activity has been proposed as a method to inhibit muscle loss. The LACE clinical trial was designed t
Externí odkaz:
https://doaj.org/article/8651c39bcec645eeb9cc2a0bb488cd15