Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Peter Stewart Gilmour"'
Autor:
Chris De Savi, Glen Andrews, Anthony Ronald Cook, Rhona J. Cox, Peter Stewart Gilmour, Simon Young, Daniel J. Warner, Beth Parker, Dickinson Mark, Amy McDonough, Matthew Dearman, Louis C. Morrill, Rob Riley
Publikováno v:
Journal of Medicinal Chemistry. 57:4661-4676
Oral phosphodiesterase 4 (PDE4) inhibitors, such as cilomilast and roflumilast, have been shown to be efficacious against chronic obstructive pulmonary disease (COPD). However, these drugs have been hampered by mechanism-related side effects such as
Autor:
Hiroki Wada, James Pilling, Stefan Kavanagh, Peter Stewart Gilmour, Patrick J. O'Shea, Paul Courtney, K. Jane Escott, Peter A. Hall, Hitesh J. Sanganee, Malbinder Fagura
Publikováno v:
Toxicology and applied pharmacology. 272(2)
Wnt activation by inhibiting glycogen synthase kinase 3 (GSK-3) causes bone anabolism in rodents making GSK-3 a potential therapeutic target for osteoporotic and osteolytic metastatic bone disease. To understand the wnt pathway related to human disea