Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Peter Steele-Perkins"'
Autor:
Bastiaan van der Veen, Sampath K. T. Kapanaiah, Kasyoka Kilonzo, Peter Steele-Perkins, Martin M. Jendryka, Stefanie Schulz, Bosiljka Tasic, Zizhen Yao, Hongkui Zeng, Thomas Akam, Janet R. Nicholson, Birgit Liss, Wiebke Nissen, Anton Pekcec, Dennis Kätzel
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-16 (2021)
In order to identify receptors that may serve as therapeutic targets in the treatment of impulse control disorders, van der Veen et al developed a systematic target discovery approach combining behavioural chemogenetics and gene expression analysis.
Externí odkaz:
https://doaj.org/article/cd48bdbae6944aca8dc5ad44ab6da068
Autor:
Paul Knoop, Dilay Yilmaz, Rossana Paganoni, Peter Steele-Perkins, Andreas Gruber, Banu Akdogan, Hans Zischka, Kerstin Leopold, Maja Vujić Spasić
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 10, p 8948 (2023)
Mutations in the HFE/Hfe gene cause Hereditary Hemochromatosis (HH), a highly prevalent genetic disorder characterized by elevated iron deposition in multiple tissues. HFE acts in hepatocytes to control hepcidin expression, whereas HFE actions in mye
Externí odkaz:
https://doaj.org/article/0a0ddf7a84c9418c8c533ca821b16e3f
Autor:
Ulrike Baschant, Sandro Altamura, Peter Steele-Perkins, Martina U. Muckenthaler, Maja Vujić Spasić, Lorenz C. Hofbauer, Andrea U. Steinbicker, Martina Rauner
Publikováno v:
Trends in endocrinology and metabolism: TEM. 33(9)
Hereditary hemochromatosis (HH) is a genetic disorder in which mutations affect systemic iron homeostasis. Most subtypes of HH result in low hepcidin levels and iron overload. Accumulation of iron in various tissues can lead to widespread organ damag
Autor:
Bastiaan, van der Veen, Sampath K T, Kapanaiah, Kasyoka, Kilonzo, Peter, Steele-Perkins, Martin M, Jendryka, Stefanie, Schulz, Bosiljka, Tasic, Zizhen, Yao, Hongkui, Zeng, Thomas, Akam, Janet R, Nicholson, Birgit, Liss, Wiebke, Nissen, Anton, Pekcec, Dennis, Kätzel
Publikováno v:
Communications Biology
Pathological impulsivity is a debilitating symptom of multiple psychiatric diseases with few effective treatment options. To identify druggable receptors with anti-impulsive action we developed a systematic target discovery approach combining behavio