Zobrazeno 1 - 10
of 369
pro vyhledávání: '"Peter Solár"'
Autor:
Terézia Hudáková, Martina Šemeláková, Peter Očenáš, Mária Kožurková, Kristína Krochtová, Simona Sovová, Zuzana Tóthová, Zuzana Guľášová, Peter Popelka, Peter Solár
Publikováno v:
BMC Complementary Medicine and Therapies, Vol 24, Iss 1, Pp 1-11 (2024)
Abstract DNA topoisomerases regulate conformational changes in DNA topology during normal cell growth, such as replication, transcription, recombination, and repair, and may be targeted for anticancer drugs. A DNA topology assay was used to investiga
Externí odkaz:
https://doaj.org/article/1912b47f60754379b54fb7b761c8a955
Publikováno v:
Fluids and Barriers of the CNS, Vol 19, Iss 1, Pp 1-79 (2022)
Abstract The response of the blood–brain barrier (BBB) following a stroke, including subarachnoid hemorrhage (SAH), has been studied extensively. The main components of this reaction are endothelial cells, pericytes, and astrocytes that affect micr
Externí odkaz:
https://doaj.org/article/e702cc5865ea4656b17344721d00b951
Autor:
Peter Solár, Zdenek Mackerle, Michal Hendrych, Petr Pospisil, Radek Lakomy, Hana Valekova, Marketa Hermanova, Radim Jancalek
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
High-grade gliomas are primary brain tumors with poor prognosis, despite surgical treatment followed by radiotherapy and concomitant chemotherapy. We present two cases of long-term survival in patients treated for high-grade glioma and concomitant pr
Externí odkaz:
https://doaj.org/article/018621220dc84f3ea078271f550e5f74
Autor:
Zuzana Tóthová, Martina Šemeláková, Katarína Bhide, Mangesh Bhide, Andrej Kováč, Petra Majerová, Monika Kvaková, Jana Štofilová, Zuzana Solárová, Peter Solár
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 10, p 8482 (2023)
The erythropoietin receptor (EPOR) is a transmembrane type I receptor with an essential role in the proliferation and differentiation of erythroid progenitors. Besides its function during erythropoiesis, EPOR is expressed and has protective effect in
Externí odkaz:
https://doaj.org/article/88a435e5e0c34f05bc1fa1cda85257d3
Publikováno v:
Acta Chimica Slovenica, Vol 68, Iss 1, Pp 151-158 (2021)
Phytoalexins are substances with antimicrobial properties produced by plants after being attacked by microorganisms, especially phytopathogenic fungi and viruses. They are also currently being studied for their antitumor effect. We aimed to study the
Externí odkaz:
https://doaj.org/article/7c3f5adb8caf44abba3834f87a7f169a
Publikováno v:
Fluids and Barriers of the CNS, Vol 17, Iss 1, Pp 1-29 (2020)
Abstract The choroid plexus (CP) forming the blood–cerebrospinal fluid (B-CSF) barrier is among the least studied structures of the central nervous system (CNS) despite its clinical importance. The CP is an epithelio-endothelial convolute comprisin
Externí odkaz:
https://doaj.org/article/03f1f933f7a3440ebb4f42583e75cec7
Autor:
Barbora Fecková, Patrícia Kimáková, Lenka Ilkovičová, Erika Szentpéteriová, Mária Macejová, Ján Košuth, Anthony Zulli, Nataša Debeljak, Petra Hudler, Karin Jašek, Ivana Kašubová, Peter Kubatka, Peter Solár
Publikováno v:
BMC Genetics, Vol 20, Iss 1, Pp 1-9 (2019)
Abstract Background Erythropoietin receptor (EPOR) is a functional membrane-bound cytokine receptor. Erythropoietin (EPO) represents an important hematopoietic factor for production, maturation and differentiation of erythroid progenitors. In non-hem
Externí odkaz:
https://doaj.org/article/722d71311911480ba3f46086b56b6655
Autor:
Vlasta Demeckova, Dagmar Mudronova, Sona Gancarcikova, Peter Kubatka, Karol Kajo, Monika Kassayova, Bianka Bojkova, Marian Adamkov, Peter Solár
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 12, p 6374 (2022)
Due to the physiological complexity of the tumour, a single drug therapeutic strategy may not be sufficient for effective treatment. Emerging evidence suggests that combination strategies may be important to achieve more efficient tumour responses. D
Externí odkaz:
https://doaj.org/article/ac72208155704c8da201df42f9fe3bca
Publikováno v:
Acta Chimica Slovenica, Vol 65, Iss 4, Pp 842-846 (2018)
We have recently shown that erythropoietin receptor (EPOR) protects cancer cells from tamoxifen (TAM)-induced cell death in the absence of erythropoietin (EPO). In this study, we analyzed the effect of EPOR silencing and EPO treatment on the response
Externí odkaz:
https://doaj.org/article/70c2ac6a02434d15b1a3237b0d0eac45
Publikováno v:
Acta Chimica Slovenica, Vol 65, Iss 4, Pp 875-881 (2018)
Acridine derivatives were first used as antibacterial and antiparasitic agents, later as antimalarial and anti-HIV drugs, and now as potentially anti-cancer agents due to their high cytotoxic activity. Due to their serious adverse effects, new synthe
Externí odkaz:
https://doaj.org/article/3fee8cdc411249aeb1d899358c2712e0